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Ota nevus, also known as brownish blue nevus on the palate and melanocytic hyperplasia of the eye, is a gray-blue patchy lesion that affects the sclera and ipsilateral face along the ophthalmic branch and maxillary branch of the trigeminal nerve as first described by Ota in 1938, and is more likely to occur in people of color, such as Oriental and black. It is more common in women. It is most common in the periorbital, temporal, nasal, forehead, and zygomatic bones.
Pigmented spots about a few centimeters in size may be grayish-blue, blue-gray, grayish-brown, black, or purple, and the patches are unevenly colored, spotted or reticulated with ill-defined boundaries. It is generally brown patchy or reticulated, while blue is more diffuse. The color of the pigmentation also often darkens with age, and the area increases.
Skin lesions can affect the nasal mucosa and ocular mucosa, causing glaucoma.
Hebei Provincial Hospital of Traditional Chinese Medicine has invested in the introduction of dozens of advanced equipment, advanced technology, which can effectively remove all kinds of birthmarks and have high patient satisfaction.
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I also have a lot of moles and want to go.
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Ota nevus, also known as the brownish-blue nevus of the upper palate, was first reported by Dr. Ota in Japan in 1938, so it is called Ota nevus. This is a dermal melanin increase disease, which is also known as the "appearance killer" because it occurs on the face.
Most Ota nevi occur in the first year of age and are confined to the first two branches of the trigeminal nerve in the face. In the early stages of the disease, Ota nevi appears as pale blue patches, and with age, the area of Ota nevus gradually expands and the color gradually deepens, turning blue-blue, blue-brown, and blue-black. At the same time, the sclera of the eyeball, oral mucosa and other parts can also appear indigo.
Chengdu Jinyi Hospital introduced that due to the great impact on appearance, patients with Ota nevus are often burdened with heavy psychological pressure, whether in school or in society, they will suffer from other people's strange eyes, and some people become inferior and autistic, and have a serious impact on future marriage and job hunting. It is advisable to standardize as soon as possible**.
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The causes of Ota nevus are mainly related to 2 factors:
1.The cause of the formation of Ota nevus, the vast majority of patients with Ota nevus are related to melanin deposition.
Ota nevi appear on the patient's face around the eyes, and generally appear as blue or gray-black patches, so it is related to pigmentation. This is due to the fact that during embryonic development, some melanocytes are left behind and stay in the dermis during the migration of melanocytes from the neural crest to the epidermis at about 11 weeks.
2.The cause of the formation of Ota nevus, a small number of patients with Ota nevus, is related to genetic factors.
Ota nevus may be autosomal dominant, and damage is usually present in the trigeminal nerve.
1st and 2nd branch areas; We can observe that most patients are born with Ota nevus, and if the parent has Ota nevus, then there is a high probability that the offspring will have the disease.
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Ota nevus is generally caused by the accumulation of pigment cells in the dermis, but patients don't have to worry too much, there is still a great hope that they can recover to health as soon as possible**!
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It may be related to heredity, it is autosomal dominant inheritance, during embryonic development, when melanocytes migrate from the neural crest to the epidermis, for some reason fail to pass through the epidermis and dermis junction, and stay in the dermis and form a lesion. Some studies suggest that it may not be a remnant of melanocytes, but a hamartoma or mole-like lesion similar to a blue nevus.
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Ota nevi are usually caused by pigment accumulation.
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Is it a piece? How much area?
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The occurrence of field nevus may be related to heredity, belonging to autosomal dominant inheritance, which is often formed in the first trimester of pregnancy** embryonic cell formation, which is a congenital melanin pigmentation that occurs in the dermis. It is more common on the face, most commonly in the eyes, temporal, and cheek areas. Generally, it will subside after a few laser shots**.
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Ota nevus formation factors.
1. Environmental pollution.
The air people breathe, the food and water they eat, and even the subtle radiation contamination can cause a green birthmark.
2. Abnormal development in the embryonic stage.
At 11 weeks of fetal life, melanocytes move from the neural crest to the epidermis and remain in the dermis, resulting in a blue birthmark.
3. Estrogen causes.
Studies have found that the presence of estrogen, progesterone, and estrogen receptors in dermal melanocytes in some patients is associated with the occurrence and aggravation of blue birthmarks.
4. Genetic factors.
Relevant biologists have pointed out that some blue birthmarks (Ota nevus) are related to genetic factors, and the corresponding chromosomes or genes cannot be determined at present.
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What are the aspects of Ota moles?
1. Disease**:
1. Intradermal Ota nevus is differentiated from Ota nevus cells, which are more mature small Ota nevus cells and enter the dermis and its surrounding connective tissue.
2. Junction Ota nevus, Ota nevus cells are at the junction of epidermis and dermis, showing multiple nests, with clear boundaries and uniform distribution distance; The upper half of each nest is in the lower layer of the epidermis, and the lower half is in the superficial dermis. These Ota nevus cells are large Ota nevus cells and are darkerly pigmented.
3. In the process of entering the dermis of Ota nevus, there are often intradermal Ota nevi and residual junction Ota nevi at the same time, which is a mixed form of the above two types of Ota nevus.
2. Pathological changes:
1. Junction Ota nevus: The limited cell nest of Ota nevus is located at the junction of the true and epidermis.
2. Intradermal Ota nevus: The nest of Ota nevus cells is located in the dermis, in which multinucleated Ota nevus cells can be seen.
3. Compound Ota nevus: The nest of Ota nevus cells is found at the junction of the true and epidermis and the upper part of the dermis, and the cells of the dermis Ota nevus are cubic at this junction, and the cells of the Ota nevus at this junction are small and contain little pigment.
The reason why Ota nevus is difficult to cure.
1. Wrong concept: extensive**, relying solely on anti-Ota nevus drugs and simple** control of the condition cannot achieve ** Ota nevus from the root.
Second, the method is not scientific: a single method is the main, the traditional Ota nevus technology includes transplantation, grinding, chemical peeling, and liquid nitrogen freezing, but it is easy to cause serious trauma if it is not appropriate.
3. Lack of equipment: The medical technology of many hospitals has not been updated, and the equipment of Ota nevus is not excellent enough, which affects the effect of the hospital.
Fourth, the shortage of technical talents: some hospitals lack the most advanced experts in Ota nevus, and the doctors' technical level is not too strong, so they cannot provide patients with multi-faceted services and meet the needs of different levels of medical treatment.
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Ota nevus is a kind of birthmark, Ota nevus, more likely to occur in people of color, such as Oriental and black, also known as brown and cyan nevus on the palate, eye ** melanocyte hyperplasia, skin lesions are gray-blue, blue-gray, gray-brown, black or purple pigmented spots, uneven coloration of the patches, spotted or reticulated, sometimes the eyelid conjugated membrane, cornea also has pigmented spots, a small number of patients have similar damage to the oral and nasal mucosa, the threat is great, need to stay away, what is the formation of Ota nevus?
The exact cause of Ota nevus is not particularly clear, but it is believed that the disease occurs when the embryo is developing, such as when melanocytes move to the epidermis at 11 weeks. **When the following melanin goes up to the epidermis and dermis junction, due to some special or accidental reasons, it leads to the formation of this disease.
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Ota nevus is also known as brownish blue nevus on the palate of the eye, dermal melanocytosis of the eye, black lesions of the eye, and melanocytosis of the ocular mucosa. It is a grayish-blue patchy lesion that affects the distribution of the sclera, conjunctiva, and ipsilateral trigeminal nerve. It is recommended to go to a regular hospital for professional **, so that Ota nevus will not be a problem!
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Ota nevus itches after the laser, it may be ** is absorbing the laser, and it will generally disappear soon, it's nothing, laser to remove Ota nevus is currently a more commonly used method.
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As a congenital facial pigmentation disease, Ota nevus has a certain hereditary nature, and it is not an absolutely hereditary pigment disease. If the parents have a facial Ota nevus, the children have a certain chance of inheriting, don't worry too much about this, even if the Ota nevus appears, it will use laser**, and the effect of multiple lasers** is okay. There is pigmentation on the sclera or retina, which is not easy to treat the eye, but it can still be treated, and this disease only affects the appearance.
1. As I just said, if we have Ota nevus, there will be an enlargement of the phenomenon, and some patients will have some darkening of the color, at this time we are going to be very good, or the condition will have a very serious change.
2. There are many ways to carry out our Ota nevus, and it is best to do it when the condition is not serious, and this is to be carried out when you are small. Our patients can use some laser methods to enter**Ota nevus, this method**Ota nevus is very good, and the general effect is very good, but the sooner ** the better.
3. Our patients' Ota nevus sometimes appears to have some ** phenomenon, at this time we also have to pay attention to it, if it is, it should be carried out as soon as possible, if it is, it is to be carried out in some regular hospitals, it must be carried out in accordance with the doctor's course of treatment, or the condition is getting more and more serious, it is difficult to say, there will be a larger area of Ota nevus.
Ota nevus is not a very serious condition, and some patients will not have some symptoms of pain and itching, which will affect the appearance of the patient. We have Ota nevus for laser ** to go to a good hospital, and there will be no scarring at this time.
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Ota nevus is a species that often coincides with the distribution of branches around the trigeminal nerve in the face, which indicates that Ota nevus often appears on the face. Therefore, it has a very serious impact on people's appearance, and it is easy to attract strange eyes from people around them in life, and often suffer setbacks in work, study, and love, and patients often suffer great psychological torture.
The formation of Ota nevus is generally due to genetic factors. Since genetic factors are the main cause of the formation of Ota nevus, many patients will have Ota nevus at birth. However, this is not absolute, and some patients with Ota nevus slowly develop after birth.
Ota moles sometimes change depending on the season, and the color will change to a certain extent, generally the color will be heavier in summer and lighter in winter.
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Ota nevus can be inherited in an autosomal dominant way, but some scholars disagree. Ota nevus lesions are mostly distributed in the trigeminal nerve.
1st and 2nd branch areas; Ota nevi can be classified into mild, medium, severe, and bilateral types. According to experts, Ota nevus is more common in people of color, such as Oriental and black people.
It is more common in women. Lesions are pale cyan, grayish-blue, brownish blue to blue-black, or brownish-yellow patches or spots with dark patches** with faded margins, and occasionally some areas of pigmented spots may be raised or even small nodules the size of milia to mung beans may occur. The spots are distributed in clusters, with different densities, or ** are patches with spots at the edges.
The color of the lesions is aggravated by sun exposure, exertion, menstruation, and pregnancy. The ideal effect can be achieved by using laser for Ota nevus**, and it generally takes 3-7 times** to achieve near-complete regression. **The interval is about 3 months.
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Ota nevus is a dermal melanocytic proliferative benign tumor that manifests as hyperpigmentation of the mucosa and can also involve other organs.
Psychological impact: Ota nevus that occurs on the face cannot be hidden, and the gaze of others often hits the soul of children with Ota nevus, resulting in low self-esteem.
Affect appearance: obvious birthmarks on the face are easy to be looked at by others, which makes the patient psychologically suffer a great blow; Children, in particular, are more likely to have low self-esteem or autistic tendencies in the process of growing up.
Health Impact: A small number of Ota nevi will be combined with abnormalities of body organs, and there is often a possibility of malignant changes.
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Ota nevus is a common cyan birthmark, for its formation, but there are different opinions, no matter which is correct, timely ** is also the most important, because it seriously affects the personal image, the face of Ota nevus is sometimes like a flaw on the jade, affecting people's appearance and mental health. Ota nevi that affect the mind, face, neck and other obvious locations cannot be hidden, and the gaze of others often hits the mind of children with Ota nevus, resulting in low self-esteem. Affecting the appearance, Ota nevus greatly affects the external image, which has become the first major factor in the child's **Ota nevus.
Most of the nevi of Ota are located on the face, neck, and limbs, and are classified as cyan, red, black, and so on.
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2 Sex hormones: Hormonal changes during pregnancy can be triggers, and progesterone also plays a role in the occurrence of Ota nevus.
3. Lack of sleep: Poor rest and less sleep time can easily lead to fatigue and lack of energy, and Ota nevus will also worsen.
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Because of the infection of germs, not paying attention to hygiene, eating junk food, staying up late often, being traumatized, and being exposed to ultraviolet rays, these are all causes.
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