Is there a genetic predisposition to cancer? Which cancers are genetically predisposed?

It is generally believed that congenital genes, acquired lifestyle, and occupational environment are all involved in the onset of cancer, but poor lifestyle is the most important carcinogenic factor, which is related to the incidence of cancer in 3 4 percent, so it is important to consider a reasonable lifestyle and appropriate dietary habits from the perspective of cancer prevention. Even in people with a genetic predisposition to cancer, the onset of the disease must be conditioned by environmental factors. In fact, in most cases, it is not the tumor itself that is directly inherited, but only a predisposition (or susceptibility) to the tumor.

On the basis of this genetics, it is also necessary to have the continuous action of external environmental factors, and undergo further changes before tumors can occur.

I wonder if my father is genetically predisposed to liver cancer?

There is a certain family inheritance, not all people. It mainly depends on your habits.

If my boyfriend also has a family history of liver cancer, can we get married and have children? (Note: He is in good health).

Of course, if there is a dispatch and a dispatch, then it is a little more likely, but it is not absolute, it mainly depends on the size of your habits. It is necessary to have good habits to avoid it.

Cancer and genetics are related.

But it is more affected by the environment, living habits, and mentality.

First of all, you need to check whether your boyfriend and you have liver disease.

If you have liver disease now, the likelihood of getting liver cancer in the future is much higher.

If not, as long as you pay more attention to your diet and lifestyle habits in the future, and maintain good health, it will have no effect on fertility.

The first is thyroid cancer. It has been clinically found that if there are 3 or more cases in parents, children and siblings, the probability of inheritance is more than 94%. The second is stomach cancer.

5-10% of gastric cancers are hereditary. The third is lung cancer. Epidemiological reports show that if a close relative has lung cancer and smokes himself, the probability of developing lung cancer is 14 times higher than that of ordinary people.

It can only be said that there is a genetic predisposition, and it is not necessarily the disease.

It should be okay to get married and have children.

A family history of genetic disease refers to a family member's weak resistance to the prevention of a disease. As long as you pay more attention to exercise and maintenance, you can effectively prevent the occurrence of diseases.

There are genetic cases. But whether you get sick or not depends on your own creation! God bless you!

Which cancers may be 'ancestral'.

Objectively speaking, cancer is a polygenic genetic predisposition disease, and some cancers do have a familial genetic predisposition, if you have these conditions in your family, you need to pay special attention (for example, if others drink, you should not drink because you may have a higher risk of developing a certain cancer than others!). ）

1. Cervical cancer: For example, Anita Mui's sisters are typical family heredity (of course, it may also be related to HPV infection).

2. Breast cancer: Under normal circumstances, if a mother or sister in the family suffers from breast cancer, the probability of her daughter or sister suffering from breast cancer is about 3 times higher than that of ordinary women.

3. Colorectal cancer: There is a relatively common term 'polyp', familial colon polyps are easy to develop into colorectal cancer (generally regarded as a precancerous lesion), if the parents have colorectal cancer caused by the above diseases, their children are as likely to suffer from the same kind of cancer as high as 50%.

4. Liver cancer: There is obvious familial aggregation of liver cancer, especially related to some genetic defects. If the parents are diagnosed with liver cancer, the risk of liver cancer is high, and if the parents are chronic hepatitis B patients or carriers (often heard of "big three yang, little three yang"), especially if the liver cirrhosis of hepatitis develops and turns into liver cancer, it is necessary to be more vigilant.

5. Lung cancer: People who have first-degree relatives (parents and siblings) who have lung cancer patients have a greater chance of developing lung cancer, and women have a higher risk than men. Studies have shown that the proportion of female lung cancer patients with a family history of cancer in China is higher than that of male patients.

In particular, in patients with squamous cell carcinoma of the lung, there is a family history; In women with alveolar cell carcinoma, there is a family history of them.

7. Prostate cancer: If an immediate family member suffers from prostate cancer (father, grandfather or brother), the risk of prostate cancer will be doubled. The relative risk of prostate cancer in two or more first-degree relatives increases to 5 to 11 times.

8. Nasopharyngeal cancer: There is an obvious familial genetic tendency, and nasopharyngeal cancer is not only that, but also ethnic susceptibility (East Asian races, especially in Guangdong and Guangxi), regional clustering (high incidence in the southern coast of China, especially in the Pearl River Delta and Hong Kong in central Guangdong), and even has a nickname called 'Guangdong cancer'. Nasopharyngeal carcinoma has also been found to be associated with Epstein-Barr virus infection.

9. Pancreatic cancer: Familial pancreatic cancer refers to the fact that at least three members of the family or at least two first-degree relatives (such as parents, children or siblings) have been diagnosed with pancreatic cancer, so that the risk of pancreatic cancer in healthy members of the family will be several times higher (and it often occurs before the age of 50, young and middle-aged people should pay attention).

Clinically, some tumors are hereditary, which is a genetic predisposition to cancer caused by a susceptibility gene. In particular, malignant tumors like germ cell mutations are hereditary. There is also a familial form of breast and ovarian cancer in clinical practice, which may indeed be caused by changes in the BRCA1 and BRCA2 genes, resulting in a high incidence of familial breast cancer or ovarian cancer.

There are also some colon tumors, which may be a high incidence of colon polyps, and this high incidence does have the possibility of malignant transformation in clinical practice. Therefore, we must pay attention to the similarity of some diseases in the clinical process, and there are indeed some diseases that have a certain familial aggregation.

There is also a kind of familial aggregation that has nothing to do with heredity, most of which is due to the fact that family members have similar living environments, similar eating habits, and the joys, sorrows, and joys in life are basically the same, and there is a relatively consistent environment for acquiring diseases, and at this time there may be a familial aggregation of certain diseases. For example, esophageal cancer and stomach cancer, it is possible that a family has a preference for certain foods, or the intake of fresh vegetables and fruits in this area is reduced, and more pickled foods are eaten, and similar stomach or esophageal diseases may occur.

The incidence of nasopharyngeal cancer has a certain correlation with betel nut, and everyone in a region or a family likes to chew betel nut, and chewing betel nut does have a certain possibility of high incidence of nasopharyngeal cancer. This is indeed not a genetic factor, it is mainly related to life factors and environmental factors, so at this time, we must pay attention to distinguish whether it is genetic or caused by environmental lifestyle.

Cancer has a certain hereditary nature, but not all people will inherit it, inheritance is usually caused by genetic inheritance, through the influence of acquired factors, such as dietary habits, living environment, etc., resulting in the appearance of cancer. People with genetic risk need to pay close attention, regular physical examination, can be preventive**, such as breast wool dan, such as cancer high-risk groups can remove the breast in advance.

There are two types of hereditary cancers, one is hereditary cancer, which is caused by genetic abnormalities, mostly due to gene mutations, deletions, and chromosomal ectopies. The other is hereditary predisposition cancer, which is caused by abnormal development, such as rectal cancer, which is often detected late, and has related cavity initiation genes and related predisposing factors, and then cancer.

Here are some cancers with a clear genetic predisposition:

Breast cancer: Women with a family history of breast cancer have a more than twice higher risk of developing breast cancer than the average woman.

Ovarian cancer: Women with a family history of ovarian cancer also have a more than twice higher risk of ovarian cancer than the average aggressive woman.

Colorectal cancer: People with a family history of colorectal cancer have a more than twice higher risk of colorectal cancer than the general population.

Prostate cancer: Men with a family history of prostate cancer also have a more than twice higher risk of developing prostate cancer than the average male.

Stomach cancer: People with a family history of stomach cancer also have a more than twice as high risk of developing stomach cancer as the general population.

Melanoma: People with a family history of melanoma also have a more than twice as high risk of developing melanoma as a regular hail friend.

It is important to note that even if there is a genetic predisposition, it is not necessary to develop cancer. At the same time, even if there is no genetic predisposition, it does not mean that you will not develop cancer. Therefore, regular check-ups and lifestyle changes are important measures to prevent cancer.