If the blood routine is normal, is it possible that it is thalassemia? 10

Thalassemia cannot be detected by routine blood tests, which is sexually inherited and occurs in boys. You can consult a specialist in obstetrics and gynaecology for reproductive intervention.

According to data, in Guangxi, Guangdong, Hainan and other southern provinces and regions, the carrier of thalassemia gene is as high as more than 20%. Since there is no statutory premarital examination as a "barrier", many young people get married with a marriage certificate, simplifying a lot of cumbersome procedures from the marriage procedure, but also burying a lot of hidden dangers, and the incidence of thalassemia in the two regions is increasing year by year. If the couple spends up to a few hundred yuan for a physical examination before marriage, they can find out whether they have thalassemia and other diseases, so as to lay the foundation for post-marriage fertility planning and eugenics.

However, many young people may not do this, and the consequence is to give birth to a child with thalassemia, which cannot be solved by a few hundred yuan, and will bring a series of family embarrassments and countless medical expenses, and a happy family may also be overshadowed by this. Therefore, young friends, in order to ensure the sublimation of your love, the happiness and fulfillment of your family after marriage, and the birth of a healthy baby, it is best for you to have a premarital check-up.

1.You are iron deficient. Serum ferritin is low and high in transferrin, which is a textbook iron deficiency, and it does not happen overnight.

In the case of girls, the possible cause is an unreasonable diet, low intake of red meat, or excessive blood loss over a long period of time (menstrual hemorrhoids). If it is a man and there is no obvious gastrointestinal disease and blood loss, it is necessary to pay attention to it and go to the hospital for further examination. Note that both men and women have blood loss, and iron supplementation without eliminating the source of blood loss is useless, and anemia will only get worse.

2.HBF is high, and thalassemia is highly suspected, while thalassemia is not excluded. Mild and moderate are possible, and genetic testing for thalassemia is recommended.

To sum up, you are iron deficient (diagnosed) + thalassemia (very likely) coexisting. It is advisable to go to the hospital for further testing of these two areas** (iron deficiency).

At ordinary times, you can eat more iron-rich foods, such as pork liver, beef liver, chicken and duck liver, pork loin, pork belly, beef kidney, beef lung, beef juice, egg yolk powder, dried whitebait, dried yellow croaker and other meat dishes, and you can also eat more spinach.

In addition, in addition to diet, you can insist on 2 cups of Xueying tea every day, which can combine blood and qi supplementation, and replenish both qi and blood.

Analysis:

Thalassemia is a group of hereditary hemolytic anemias, and the clinical symptoms of this group of diseases vary from mild to severe, and most of them manifest as chronic progressive hemolytic anemia.

Guiding opinions: 1. Thalassemia cannot be seen from routine blood examination.

2. The diagnosis of this disease requires genetic testing, which is caused by the deletion or point mutation of globin gene.

It is recommended that you first go to the hematology department for a blood routine, urine routine, liver and kidney function tests to see what type of anemia it is. Mutton is eaten together with lotus root, pork loin and fungus, which is a good way to nourish blood and eat therapy.

Routine blood tests cannot confirm whether thalassemia is diagnosed, and thalassemia genetic testing can confirm the diagnosis. However, the complete blood test has a suggestive effect, thalassemia belongs to small cell hypochromic anemia. If the routine blood test presents such a condition, in the area of the combined patient.

Age-related physical examination can be indicative. Because iron deficiency anemia can also cause microcytic hypochromic anemia.

A complete blood test cannot rule out thalassemia, but your results suggest that thalassemia is unlikely, and even if it does, it is quiescent (gene carrier).

Your red blood cell index is basically normal, and it doesn't matter if your hemoglobin (HGB) and red blood cell count (RBC) are slightly higher, and if you are a man, you can even say that it is completely normal.

Why do you suspect thalassemia?

If it is because the spouse has thalassemia or has a family history of thalassemia, genetic testing for thalassemia is recommended.

Generally, thalassemia will be checked with hemoglobin electrophoresis, but considering that your blood routine does not show any signs of thalassemia, it is unlikely that hemoglobin electrophoresis will find abnormalities, so it is recommended to perform genetic tests directly.

If red blood cell fragility is low, it is recommended to check for G6PD activity.

Thalassemia, also known as marine anemia, is a group of inherited hemolytic anemias. The common feature is that one or more of the globin peptide chains in hemoglobin are synthesized or not synthesized due to defects in the globin gene. As a result, the composition of hemoglobin is changed, and the clinical symptoms of this group of diseases vary from mild to severe, and most of them manifest as chronic progressive hemolytic anemia.

Unfortunately, it is difficult to diagnose thalassemia from a blood routine alone. If there is a decrease in serum ferritin content, a decrease in sideroblasts outside the bone marrow, and an increase in erythrocytes in the blood routine, iron-containing preparations are used**.

If it improves, it is iron deficiency anemia, and if it is otherwise, thalassemia can be diagnosed.

There are many subtypes of thalassemia, and genetic diagnosis must be done to confirm the diagnosis.

Do you have any past medical history and any discomfort? Do you have any picky eating, special dietary habits, etc.? Basic information such as gender, age, occupation, etc.? If you are a woman, do you have heavy menstrual bleeding?

This routine blood test sheet indicates that there is a possibility of "microcytic hypochromic anemia", but you have not provided hemoglobin data, can you add it?

In the case of "microcytic hypochromic anemia", the following possibilities are common: iron deficiency anemia, thalassemia, sideroblastic anemia, etc.

Sometimes, in order to clarify ** (the cause of iron deficiency), gastroscopy, colonoscopy and other examinations are also performed (considered according to the condition).

If it is determined that it is not iron deficiency anemia, thalassemia is more likely, and the diagnosis needs to be confirmed by asking family history and assisting in hemoglobin electrophoresis examination. Since thalassemia is inherited in an autosomal dominant manner, if the patient is young, it is necessary to check whether the other half has this problem before preparing to have children.

One of the hematologic disorders may also have these manifestations, called sideroblastic anemia, but it is rare and not considered first.