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Oral lichen planus is a chronic condition with a generally good prognosis. Since the first reported cases of oral lichen planus carcinogenesis in the early 20th century, some new cases have been added one after another, and gradually attracted attention to the precancerous nature of lichen planus. In the last decade or so, including some monographs, the disease has been classified as precancerous, and oral lichen planus should be at least considered as cancerous like leukoplakia.
Reported carcinogenesis rates are 1% to 10%, but most are less than 1%.
There are three main reasons for considering lichen planus as a precancerous state:
1) Many clinical follow-up studies have found that lichen planus does have cancerous changes;
2) find the link between the disease and carcinogenesis in histopathology;
3) Experimental studies have found that transplantation of lichen planus damage suspension into nude mice can cause cancer;
4) Studies using autoradiography technology have shown that oral lichen planus shows images of precancerous lesions;
5) Quantitative histology, ultrastructure, anti-keratin antibodies, blood group antigens, immunohistochemistry and related oncogene or tumor suppressor gene testing showed that oral lichen planus did have carcinogenesis potential.
From the above, it can be seen that although the carcinogenesis rate of oral lichen planus is not high, it does have the possibility of cancer, and it is basically a well-differentiated squamous cell carcinoma after cancer. Therefore, it is of great significance to strengthen clinical follow-up for the timely detection or prevention of oral lichen planus.
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Oral lichen planus has the potential to become cancerous but the probability is not high, oral lichen planus is related to infection, endocrine, mental stress and other factors, and glucocorticoids can be used after the occurrence of oral lichen planus**. You can drink plenty of water, keep your mouth clean and avoid excessive stress.
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How long does it take for lichen planus to become cancerous.
Everyone's condition is different. For lichen planus, Western medicine mostly uses antibiotics, vitamins, immune preparations, hormones, etc., and in severe cases, surgical resection is used, but the effect is not ideal. Traditional Chinese medicine believes that the oral mucosa is caused by emotional failure to damage the heart and spleen, or yin deficiency and fire, heat poison and burning, or internal heat attacking the mouth.
Stress, fatigue, lack of sleep, and menstrual cramps in women can induce or aggravate the disease. At the same time, there is a certain genetic predisposition to the disease.
How long does it take for lichen planus to become cancerous.
First of all, it is necessary to make it clear that the main factors that induce oral lichen planus are: endocrine factors, infectious factors, psychiatric factors, immune factors, trace element deficiencies and certain systemic diseases (diabetes, infection, hypertension, digestive tract dysfunction).
clarified the reason why he suffered from oral flattening lichen, and then filial piety striker did targeting**.
What is the risk of lichen planus becoming cancerous?
Hello, the probability is relatively small, we have not encountered it here, the probability is very low, the main thing you need to cooperate with is targeted.
I've had oral lichen planus for more than 20 years, can it become cancerous?
Whether it is cancerous or not depends on many factors, and it can only be said that it is possible.
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The influence of lichen planus is mainly related to autoimmunity, endocrine regulation, bacterial infections, systemic diseases, genetic factors, mood and mental factors. However, it is not possible to determine with certainty at this time.
1.Viral and bacterial infections were thought to be associated with the infectious factors in the early days, but there was no conclusive evidence.
2.Patients with mental and neurological factors are affected by physical and mental activities due to environment, family, work, personal life and other reasons, and are mentally traumatized, nervous, anxious, depressed, etc., causing a series of psychological, pathological, biochemical and metabolic changes in the body, resulting in disorders and disorders.
3.Endocrine factors are more common in women, and the fluctuation of the condition is related to pregnancy, menopause and some drugs that affect endocrine function. The estradiol and testosterone levels in patients are usually lower than normal.
4.Trace ElementsWhen the trace elements in the patient's hair were detected, zinc, iodine, etc., were found to be lower than normal, while nickel was higher than normal.
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First of all, the patient himself perceives different degrees of itching, and the acute generalized type of **lichen planus is accompanied by a severe itching sensation. **The lesions of lichen planus are mostly triangular or polygonal flat papules that are purplish-red or red in color, waxy shiny or thicker and rough, and are densely flaky, band-like, or diffuse, respectively.
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If left untimely, lichen planus can cause hair loss, nail loss, and even cancer.
1.Affect daily life: This disease can bring itching and discomfort, which has a certain impact on daily life.
2.Affect the appearance and increase the psychological burden: When lichen planus is severe, it will cause hair loss and nail removal, which will not only affect the appearance, but also cause anxiety, depression and other bad emotions, increasing the psychological burden.
3.Causes cancer: Lichen planus can become cancerous. Those who take arsenic, have multiple X-rays or smoke for a long time are more likely to become cancerous.
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**Disease often appears in our lives, lichen planus is a kind of thing, will appear in us** or hair follicles like erythema, a friend of mine has such a disease, so, what is lichen planus, and I will introduce it to you.
1.First of all, lichen planus is a chronic inflammatory disease of unknown cause, mainly in middle-aged people, after getting the disease, there will be red and swollen plaques at the **, the condition is different, and the performance will be different.
2.Secondly, it appears as a small, purplish-red, polygonal flat papule with a shiny surface and white reticular stripes (Wickham lines), and the rash is mostly distributed on the flexor side of the wrist and forearm, and the nape of the hand, forearm, neck, and sacrococcygeal, and can form a new rash with a linear distribution at the scratching site (homomorphic reaction).
3.Eventually, the patient feels itching, and the rash may subside after months to years, leaving some pigmented patches. Lichen planus can involve mucosal sites, most commonly in the oral cavity, and manifest as heavy white reticulate fine lines on the buccal mucosa, erosions, ulcers, bullae, and burning.
Some patients develop lichen planus, which is characterized by thickening, roughness, bumpiness, or atrophy of the nail plate, which is characterized by pterygium, which is absent and the nail cuticle covers the nail bed anteriorly.
Precautions. After having lichen planus disease, it is necessary to check and ** in time, and at the same time, like other ** diseases, patients should pay attention to ** hygiene, and at the same time should be conditioned in their daily diet, eat more fresh fruits and vegetables.
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To ** lichen planus, you can go to the director of the Department of Immunology of the Department of Oral Mucosa on the second floor of the Fire Hospital of the Jilin Provincial Public Security Department and Dr. Wen Shuang, they are not only proficient in medical skills but also very serious and responsible, but also very concerned about the patient's psychological condition, timely dredging, enlightenment, my mother's illness is what Dr. Sun is optimistic about, we are all grateful to him.