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Behavioral studies have shown that inhibition of the parabrachial nucleus can also reduce itch-scratching behavior.
Adeno-associated virus expression in the experimental group and the control group injected into the parabrachial nucleus.
Pharmacogenetic inhibition of the effect of the parabrachial nucleus on itch-induced scratching behavior.
This work reveals for the first time a long-range neural circuit that transmits itch information from the spinal cord to the brain, proves that the parabrachial nucleus is a key node in the itch information processing circuit, and further clarifies the important role of this brain region in chronic itch and allergic itch. This study lays a foundation for in-depth analysis of how itch information is processed in the brain, and provides a new direction for finding potential targets. <>
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Question 1: What is the feeling of tickling People have nerves, anywhere in the body, for example, if you are pricked by the tip of an embroidery needle, you will feel sensitive and flicker, then, if you are scratched by something soft, it does not hurt, there is a feeling, it is itchy, then you let this feeling disappear and restore the feeling that the nerve did not have, and you will feel comfortable.
Question 2: The feeling of being tickled is very uncomfortable, such as thousands of ants crawling on your itchy flesh, mainly laughing non-stop and dying of discomfort.
Question 3: Have you ever been tickled, and what does it feel like?
Question 4: What is the reason why it is difficult to feel tickled and only to do it 1 is a very good friend, if you do that. You're very sad, sad and angry.
2 If it is someone else, who is not very acquainted, you can still tolerate it (only to those who are tolerant in heart).
3 If the people in the family play with pinching, it will be very itchy and happy.
Question 5: The feeling of being tickled by a girl 20 points I really want to laugh when I think about it, and I laugh until I am angry.
Question 6: What does it feel like to be scratched on the heart of your foot? Itchy, heartburn sensation.
Question 7: What does it feel like to scratch the heart of your foot It's itchy and uncomfortable.
Question 8: What does it feel like to scratch your feet? You're funny! How we feel will you feel? Tell you: I don't feel it cracking. You want to know, just scratch your feet.
Question 9: What is the reason why I feel very uncomfortable when I feel tickled 1 I am a very good friend, if I do that. You're very sad, sad and angry.
2 If it is someone else, who is not very acquainted, you can still tolerate it (only to those who are tolerant in heart).
3 If the people in the family play with pinching, it will be very itchy and happy.
Question 10: Have you ever been tickled, and what does it feel like?
Because when we tickle ourselves, the cerebellum has already controlled the body movements, and it has also been transmitted to the brain nerves, so there will be no stress response, and when others tickle us, the brain does not respond in time, so there is a stress response.
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