Why is it that whole blood is lost in acute blood loss, but it is not necessary to have whole blood

There are many ** acute blood loss, and different ** models are used for different **, and whole blood transfusion is not necessarily suitable for all kinds of acute blood loss, because:

1. Whole blood can replenish blood volume and improve the oxygen-carrying capacity of blood at the same time;

2 Whole blood can be used in patients with shock who have lost a lot of blood and have progressive blood loss.

3 When transfusing whole blood, awareness of whole blood should be raised:

1) Acute blood loss is whole blood, and the whole blood supplemented is not "complete".

2) granulocytes and platelets in whole blood have lost their function;

3) Factor and factor in whole blood are unstable, and the activity gradually decays after leaving the body;

4) There is a lot of cell debris in whole blood, and there are many "preserved damage products";

5) The more whole blood transfusion, the heavier the metabolic burden of the patient;

6) Whole blood is more likely to produce alloimmunity than red blood cells;

7) Whole blood has more adverse reactions than red blood cells.

When we should consider the impact of volume expansion on the lungs, the total amount of volume expansion fluid, pulmonary intracapillary pressure, and the presence or absence of co-infection are more important than the type of volume expansion solution. The key is to strengthen the monitoring of cyclic dynamics during expansion; Patients with trauma and co-infection should use crystalloid-based expansion solution; Non-traumatic patients are suitable for colloid-based volume fluids; Do not lightly use plasma volume expansion or ** hypoproteinemia; Whole blood transfusions can be used for massive blood transfusions, but they are not required; If whole blood is to be transfused, whole blood with a long shelf life should not be used (containing more micropolymers).

One of the most important factors is that after blood loss occurs, fluid from the body enters the bloodstream. What is lost later is not whole blood. At this time, the transfusion of whole blood will increase the osmotic pressure of the blood colloid, and the fluid in the body will continue to enter the blood, which is not conducive to cell metabolism. It can even worsen the condition.

I don't know if I understand it right.

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(1) Patients with acute blood loss did lose whole blood, but the whole blood supplemented was not complete;

2) Patients with acute blood loss not only lose whole blood, but also have a large amount of functional extracellular fluid transferred to the third space, and the medical education network collects and sorts out the hemoconcentration;

3) Among the three main rescue measures of blood volume supplementation, hemostasis and blood transfusion, the first is to restore blood volume by infusion, followed by hemostasis (drug or surgery), and finally blood transfusion is considered;

4) The usual blood transfusion method is as follows: crystalloid, colloid, and blood dwelling should be used in combination with red blood cell treatment. If the amount of blood lost is too large or a certain amount of red blood cells has been transfused, platelet concentrate, albumin, fresh frozen plasma, and cryoprecipitate may be used, depending on the condition.

Transfusion of partial whole blood is also indicated in patients with acute massive blood loss, preferably whole blood with a short shelf life.

1. In addition to red blood cells, the concentration of other components in whole blood is low, and some have lost their function or activity during storage and cannot play a leading role.

2. The main source of active ingredients in whole blood is erythrocytes, and its efficacy is similar to that of erythrocyte products, while the adverse reactions of various other components retained in whole blood are more than those of erythrocytes.

3. Component blood transfusion has many advantages: one blood is multi-purpose, saves blood source, high product concentration and purity, good efficacy, and less mixing of other components, which can minimize the anti-response of blood transfusion and the spread of diseases.

4. For blood transfusion of non-anemia patients with acute blood loss: blood loss less than 30% of blood volume generally does not need blood transfusion, only colloid and crystal solution are supplemented. Blood loss up to 30-50% blood volume, transfusion of plasma blood or concentrated erythrocyte decacrystals, colloidal solution.

Blood loss reaches 50-80% of blood volume, blood loss of whole blood decalbumin solution reaches more than 80% of blood volume: transfusion of whole blood decacin solution, 10 fresh frozen plasma, 10 platelet concentrate.

5. For blood transfusion of other patients, it is necessary to grasp the principle of what is lacking and what is missing according to the patient's recovery ability and the life of the transfused ingredient, and the whole blood transfusion must not be uniform.

Our blood loss is the loss of red blood that is visible to the naked eye.

After the blood is collected at the blood bank, the blood is separated into different components (red blood cells, plasma, and even platelets, etc.).

Blood transfusions are divided into whole blood transfusions and component transfusions.

And our blood transfusion is not only the use of red blood cells, but also the plasma components to adjust the proportion of each component in the blood to facilitate recovery, and the plasma contains an important colloidal and nutrient - albumin.

In addition, whole blood transfusion is indicated only when the blood loss exceeds 30%, but it is generally difficult to have a stock of whole blood.

People who lose more than 3000cc of blood hang up.

Plasma is mainly a nutrient and is used when excessive blood loss leads to physical exhaustion without a severe reduction in oxygen supply, and whole blood is used if there is a severe loss of red blood cells.

This is determined in terms of hematocrit. Hematocrit is higher than 35%, and plasma transfusions are common. Less than 35% before whole blood transfusion.

When acute blood loss is greater than 30% of the blood volume, whole blood transfusion is also given.

Blood loss 10% transcrystalline colloid.

20% infusion concentrated red.

30% whole blood transfusion.

50% plus coagulation.

Patients with acute massive blood loss who are volaemically depleted and have progressive bleeding may be considered for transfusion of whole blood. Whole blood can simultaneously improve the oxygen-carrying capacity of the blood and replenish the blood volume of the spine. It is rare to use whole blood in clinical practice.

In case of excessive blood loss.

Once a person with low platelets has a wound, the wound does not heal easily and can lead to heavy bleeding.

When the human body loses blood.

400ml or less, you can rely on the body's own blood supply function to supplement, there is no danger, called "safe blood loss" when people donate blood is generally 300ml. When the blood loss is between 600 and 800 ml, it is called "dangerous blood loss", and when the blood loss is 1200 ml, it is called death blood loss, which can cause death at any time. Therefore, when the blood loss is about 600ml, blood transfusion should be given in time.

Get rid of the undesirable symptoms caused by blood loss as soon as possible. Don't put your life at risk.

There are many kinds of blood loss of more than 40% of body weight, autologous blood transfusion for smooth surgery, for certain diseases (bleeding disorders, burns, anemia,...... etcComponent transfusions, such as red blood cells, platelets, granulocytes, and plasma, are transfused into the body in high-purity or high-concentration products.