What causes muscle weakness? What is muscle weakness?

Myasthenia gravis (MG) is an autoimmune disease caused by dysfunction of transmission at the neuromuscular junction, which is clinically manifested as partial or systemic skeletal muscle weakness and fatigue, which worsens after activity and is relieved by rest. The prevalence is 77,150,100,000, with an annual incidence of 4,111,100 million. The prevalence is greater in women than in men, about 3:

2. It occurs in all ages, and children are mostly 1 to 5 years old.

The causes of myasthenia gravis are divided into two categories: one is congenital hereditary, which is very rare and has nothing to do with autoimmunity; The second group is autoimmune diseases, which are the most common. The cause of the disease is not clear, but it is generally thought to be related to infection, drugs, and environmental factors.

The causes of the problems that cause muscle weakness are:

1. Nutritional factors: The family conditions of patients with very muscle weakness are relatively poor, which may be related to long-term nutritional deficiency and fatigue. 2. Overwork: Some patients with mental stress often get sick after playing computer games and mahjong for a long time.

3. Food poisoning and contamination: A considerable number of patients are caused by eating unclean fried fritters and inferior drinks contaminated by chemicals.

4. Genetic factors: The problem of muscle weakness is also closely related to genetic factors, so those who have a history of this disease in the family should be vigilant.

Muscle weakness is mainly due to the impaired transmission function caused by the decrease of acetylcholine receptors, so I feel that I have no strength all the time, and I just can't lift it.

The most common presenting symptoms of myasthenia gravis are ptosis and diplopia in both eyes. Patients may also have muscle weakness in the extraocular muscles, laryngeal muscles, or extremities alone at the beginning of the disease. This is followed by the gradual involvement of more skeletal muscles, from the face and limbs to the respiratory muscles, affecting normal life and even life-threatening.

Typical symptoms. The main symptoms are as follows:

Ptosis of the upper eyelid: this is caused by paralysis of one or both extraocular muscles, which may be accompanied by strabismus and diplopia at the same time.

Dysphagia and chewing: This is caused by the involvement of the facial and throat muscles, and at the same time, there will be an indifferent expression, a wry smile, continuous chewing weakness, choking on water, and more laborious swallowing of chewed food when eating;

Hoarseness: This is also caused by the involvement of the facial and throat muscles, which can be accompanied by nasal speech, dysphonia, and unclear pronunciation when speaking;

Difficulty raising head: when the sternocleidomastoid muscle and trapezius muscle are involved, it manifests as neck weakness, difficulty in raising the head, weakness in turning the head and shrugging the shoulders;

Weakness of the arms and legs: The muscles of the limbs are affected by proximal weakness, which is manifested as difficulty in raising the arms, combing the hair, and climbing stairs, but the tendon reflexes are usually unaffected and the sensation is normal;

Dyspnea: Respiratory muscle involvement often leads to adverse consequences, and medical attention should be sought as soon as possible if you experience difficulty breathing;

Morning and evening severity: this is a characteristic of the symptoms of the disease, i.e., daily fluctuations, muscle weakness that worsens after exertion in the afternoon or evening and lessens after morning or rest.

In some patients, when the respiratory muscles are affected, the generalized muscle contraction weakness or even muscle weakness occurs in the short term. Myasthenic crisis refers to the dangerous phenomenon that the patient suddenly develops severe dyspnea under the influence of a certain trigger, and the patient is unable to breathe normally. Once it occurs, patients need to be presented to the emergency department quickly, and myocardial involvement can occasionally occur, which can lead to sudden death.

Predisposing factors include respiratory tract infections, surgery (including thymectomy), stress, and systemic disease

Patients with muscle weakness often present with symptoms such as generalized skeletal muscle weakness, fatigue and fatigue, and symptoms worsen after physical activity. For example, patients with speech muscle weakness, patients may have speech weakness, hoarseness and bulbar paralysis-like nasal voice, patients with swallowing muscle weakness may have pharyngeal foreign body sensation, choking on drinking water, etc., patients with cervical muscle weakness may have a crooked head position, head tilt forward and cannot be lifted. If the patient has weakness in the limbs, it can be manifested as weakness in writing, unable to hold the dishes and chopsticks, etc., and patients with severe disease may have high paraplegia.

Muscle weakness is mainly manifested as partial or systemic skeletal muscle weakness, easy fatigue, aggravation of symptoms after activity, and reduction of symptoms after rest, generally severe, long course of disease, and refractory to treatment.

There are also myasthenic diseases, which are caused by autoimmune diseases, such as myasthenia gravis, and there is no way to completely stabilize the condition through scientific treatment. For example, periodic paralysis, especially muscle weakness caused by hypokalemic periodic paralysis, the patient's muscle weakness symptoms are relatively severe, and after potassium supplementation, muscle weakness can be completely recovered, but it is easy. If it is not clear, if it is caused by some autoimmune diseases, then the effect is not good.

Myasthenia is commonly known as myasthenia gravis, which is a condition in which neuromuscular damage causes muscle weakness. It is also an autoimmune disease, and generally its common symptom is that the patient has drooping eyelids, but this is not severe and the patient is conscious.

Muscle weakness refers to a significant decrease in the strength of one or more muscles, and the muscles are unable to move normally, mainly due to central and peripheral nervous system lesions, muscle lesions and neuromuscular junction lesions.

Patients may have an acute or chronic onset, affecting all skeletal muscles first, some muscles before the whole body, or they may remain confined to specific muscles. It can manifest as drooping eyelids, dysphagia, limb weakness, motor disorders, and in severe cases, dyspnea and hemiplegia.

and other symptoms, which may be accompanied by paresthesias and abnormal vision. **The prognosis varies.

Refers to the inability of muscles to produce normal strength, and the loss of muscle strength to varying degrees. Patients feel fatigued easily and have difficulty performing activities or movements of daily or professional life. It can be detected by observing and measuring the strength of individual muscles or muscle groups.

Myasthenia is a chronic condition caused by impaired neuromuscular transmission. The clinical feature is that the affected bony muscles are highly fatigued and partially recovered with rest and anticholinesterase drugs**. The occurrence of the disease has a certain relationship with genetic factors, it can occur at any age, but it is most common at the age of 10 to 35 years, and there are also middle-aged and older patients.

What is muscle weakness, as the name suggests, is that the muscles have no strength, no ability to contract, this disease is terrible, and in the end, I can't even eat or swallow.

Independence is usually myasthenia gravis and is a condition caused by cholinergic deficiency in squid. It is light in the morning and heavy in the evening. The morning is light and the twilight is heavy.

What is the disease? Muscle weakness is the power caused by the trifurcation nerve of the main flag, the chicken trembles and is weak, and the skin of the thigh cannot be reacted to three times, and the infrastructure has no strength and cannot exercise.

1. Orthopedics is often caused by damage to spinal nerves, such as common cervical spondylosis, including cervical disc herniation or cervical spinal stenosis.

2. The lumbar intervertebral disc herniation and lumbar spinal stenosis of the lumbar spine are all due to the weakness caused by compression and injury of the cervical and lumbar spinal cords, as well as thoracic spinal stenosis, etc., which are similar reasons.

3. In the peripheral nerves, such as the ulnar nerve, radial nerve, median nerve of the upper limbs, the common peroneal nerve of the lower limbs, and even the sciatic nerve, these peripheral nerves are like the middle reaches of the river, and if something goes wrong, it may also cause muscle weakness.

4. In addition to orthopedic problems, some diseases of the whole body, such as inflammation of the spinal cord itself, such as myelitis or other problems, and even systemic endocrine electrolyte disorders, potassium, sodium, calcium, chloride, etc., may also cause muscle weakness.

Therefore, in order to determine what causes muscle weakness, it is necessary to combine the patient's medical history, clinical physical examination, and many necessary auxiliary examinations to conduct a comprehensive analysis and judgment, and it is even likely that many departments need to consult and negotiate to find the specific cause.

Myasthenia is simply a symptom of muscle weakness that can be caused by a variety of causes, such as a lesion of the muscle, a lesion at the neuromuscular junction, or a nerve injury. If it is a muscle lesion, it can be myositis, rhabdomyolysis, and various diseases caused by genetic and metabolic causes, and it is necessary to distinguish what diseases are in order to consider what causes them. If the lesion is at the neuromuscular junction, it may be myasthenia gravis, which is an autoimmune abnormality, or a paraneoplastic syndrome associated with the tumor, or a weakness syndrome involving the disease.

If it is neurogenic causes, it can be caused by any nerve damage, nerve inflammation, nerve trauma, vascular disease, and demyelinating disease. In addition, it can also be systemic diseases of the whole body, such as endocrine diseases, which will cause symptoms of muscle weakness. Therefore, muscle weakness is not simply caused by a lack of causes, it can be a variety of diseases, and it is possible to diagnose what the disease is, and then we can know what causes it.