What is gastric mucosal intraepithelial neoplasia?

If there is low-grade or even high-grade intraepithelial neoplasia in the gastric mucosa, it is necessary to be vigilant.

Summary. Hello, dear, is typing the answer for you, it takes a little time, please be patient!

Hello, dear, is typing the answer for you, it takes a little time, please be patient!

At present, for high-grade intraepithelial neoplasia lesions, surgical intervention is mostly advocated, whether to choose endoscopic submucosal dissection, laparoscopic surgery, or open surgery, which has not yet been unified, and the specific situation is as follows: 1. Endoscopic submucosal dissection: If the tumor is superficial and not more than one centimeter, endoscopic submucosal dissection can be considered after excluding the presence or absence of enlarged lymph nodes through endoscopic ultrasound and CT examination.

2. Open surgery: For large and deep lesions of the mass, or when the lesion is deep confirmed by endoscopic ultrasound and CT, and there are suspicious lymph nodes in the periphery, endoscopic submucosal dissection should not be performed, and laparotomy should be performed, and laparotomy is divided into D1 and D2 surgery, which is a problem decided by the surgeon. In general, if it is difficult to palpate the lesion during surgery, there is no clear mass, and there is no metastasis of the surrounding lymph nodes, the lymph nodes adjacent to the tumor are frozen and D1 surgery is performed.

For patients with definite lesions and enlarged surrounding lymph nodes, D2 surgery should be performed. Therefore, it is recommended that patients must strictly follow the doctor's instructions.

Intraepithelial neoplasia (IN), also known as intraepithelial neoplasia (IN), is a commonly used diagnostic term in clinicopathological diagnosis, and covers atypical hyperplasia or dysplastic lesions of epithelial tissues in multiple organs, including cervix, prostate, delayed endometrium, esophagus, gastrointestinal and other organs of the digestive system. IN is a special stage before the occurrence of epithelial malignancy, in which there are obvious changes in cell morphology and cell arrangement compared with normal tissues, and there are also genetic clonal changes in genetics, and the biological behavior is aggressive.

Analysis: According to your pathological results: high-grade intraepithelial neoplasia (moderate-severe dysplasia) can be regarded as precancerous lesions, which have not yet reached cancer. You've had a large gastric resection and the chances are slim.

Suggestions: It is recommended to appropriately strengthen acid suppression and protect the gastric mucosa after surgery**, and re-examine the gastroscopy every six months, because the postoperative pathology does not see cancerous changes and lymph nodes, there is no need for radiotherapy and chemotherapy for the time being.