AST Alt ratio is high Is there a problem 10

Analysis: Hello, ALT and AST are both enzymes that react to liver function, and the normal value of ALT is 0-40;

AST is 8—40;

Clinical significance of elevation:1

Liver disease. 1.Acute.

Viral hepatitis.

Both ALT and AST are markedly elevated, reaching 20-50 times or even 100 times the normal level. It is an important test for the diagnosis of viral hepatitis. 2.Cirrhosis.

Chronic viral hepatitis.

4.Inside and outside the liver. Cholestasis.

Myocardial infarction: acute myocardial infarction.

After 6-8 hours, AST increases, and 18-24 hours to the peak, and its value can reach 4-10 times of the upper limit; It is related to the extent and degree of myocardial necrosis. Guidance: Alt AST ratio: 1In moderate.

Hepatocellular damage.

, the ALT leakage rate is much greater than that of AST, and the sensitivity of AST assay in response to hepatocellular injury is higher than that of AST.

2.In severe hepatocellular injury, the ALT SAT in the serum is often greater than 1If the AST increase is significant, then ALT AST is less than 1.

Chronic hepatitis. the possibility of entering the active period;

Alcoholic liver disease.

, AST is markedly elevated, ALT is almost normal, and ALT AST

When the AST and ALT reference values are normal, the deviation of the two ratios from the normal reference range is not a big problem, AST is more in cardiomyocytes, and ALT is more in hepatocytes, and many people think that the two values need to be more than twice as meaningful to be meaningful. Both of your values are within the normal reference range, there should be no problem, and your test sheet I think is normal. So don't worry.

AST and ALT are enzymes commonly used in liver function tests to understand hepatocellular damage. AST is aspartate aminotransferase and ALT is alanine aminotransferase. The normal value of both aminotransferases is less than 40 IU, and more than 40 IU is considered to be abnormal liver function.

The aminotransferase value in patients with chronic hepatitis is always high, reflecting that the inflammation of hepatocytes has not stopped, and the swelling and necrosis of hepatocytes persist.

Serum AST ALT ratio is helpful in differential diagnosis. The AST ALT ratio is 1 in acute hepatitis, 1 in chronic hepatitis, and even 2 in alcoholic liver and cirrhosis, and it is helpful to diagnose alcoholic liver if primary liver cancer can be ruled out.

It is recommended to go to a regular specialized liver disease hospital for another examination, for **, symptomatic**.

It should be that the nutrition is not good.

How much higher is the indicator? If the index is higher than the higher value, then it is considered to be caused by liver disease, then there are many types of liver disease, you need a detailed and perfect examination, and gradually clear and clear, elevated aminotransferases indicate liver cell damage

ALT is the English abbreviation of alanine aminotransferase, AST is the English abbreviation of aspartate aminotransferase, and the normal ratio of ALTpast is the ratio, and the ratio is less than 1 when the ratio is less than.

Becoming one of the features of chronic hepatitis and cirrhosis is caused by the fact that when AST is manifested by significant height is combined with an ALT ratio, you can appear to be greater than one when looking for acute infection.

If the ratio of height to ST is often less than 1, it indicates chronic hepatitis, including the size of the symptomatic three-yang carrier, and this value indicates that the cell may be necrosis.

If the ratio is critical, there will be severe liver damage in one ratio of two to three, and if not taken seriously, this will develop into acute hepatic pyrum failure, and in severe cases, it can lead to death.

For liver cancer, about half of liver cancer patients show that the ALT ratio is less than 3, the more ** the ratio is, the longer the cancer progression, this ratio can be used as one of the diagnoses of liver cancer, of course, other reasons should be considered, but the performance is less than three, we should pay attention to and consider the possibility of liver cancer.

1. Causes of ALT elevation:

1) Many extrahepatic factors can be caused, such as malnutrition, alcoholism, cardiomyopathy, cerebrovascular disease, skeletal muscle disease, infectious mononucleosis and pancreatitis;

2) Some drugs and poisons that are toxic to the liver, such as chlorpromazine, isoniazid, quinine, salicylic acid preparations, ampicillin, carbon tetrachloride, organophosphorus, etc. can also be caused.

2. Reasons for AST elevation:

1) There is hepatocellular damage, which is generally seen in various hepatobiliary diseases such as hepatitis, liver cirrhosis, fatty liver, and alcoholic liver.

2) The presence of myocardial infarction or myocarditis, other diseases such as nephritis and pneumonia, and myocardial infarction are damaged.

3) Liver cell damage is severe, and even the patient has reached the level of liver cirrhosis.

4) Exercise, eating, drinking, staying up late, and drug pairs can also cause.

Disease analysis: Elevated alanine aminotransferase (also known as glutamate aminotransferase, referred to as GPT, ALT) is a very common phenomenon in clinical practice, and elevated is an important indicator of liver function problems. Among the most common factors, all types of hepatitis can cause ALT to rise, which is caused by the destruction of the liver.

Some drugs, such as antineoplastic drugs and antituberculosis drugs, can cause liver damage. Heavy drinking alcohol and eating certain foods can also cause short-term damage to liver function.

High aspartate aminotransferase (AST) indicates the presence of hepatocellular injury, which is generally seen in various hepatobiliary diseases such as hepatitis B, liver cirrhosis, fatty liver, alcoholic liver, etc., and should be further investigated to determine the cause of high aspartate aminotransferase and symptomatic **.

Opinions: Common causes of elevated aminotransferases:

1. Diseases of the liver itself, especially various types of viral hepatitis, cirrhosis, liver abscess, liver tuberculosis, liver cancer, fatty liver, Wilson's disease, etc., can cause different degrees of elevated aminotransferases.

2. In addition to the liver, other organs and tissues in the body also contain this enzyme, so when myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, Japanese encephalitis, polymyositis, acute sepsis, enteric typhoid, encephalitis, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, crush syndrome, etc., transaminases in the blood can also be seen.

3. Because transaminases are excreted from the bile ducts, if there are diseases of the bile ducts, gallbladder and pancreas, and bile duct obstruction, transaminases can also be increased.

4. Drug-induced or toxic liver damage, as well as drug allergies can cause elevated aminotransferases, often accompanied by cholestatic jaundice and hepatocellular injury. For example, when you are sick, you take drugs that can damage the liver, erythromycin, tetracycline, sleeping pills, antipyretic analgesics, contraceptives, as well as traditional Chinese medicines such as banxia, betel nut, and indigo. After these drugs are stopped, aminotransferase levels return to normal very quickly.

5. Normal pregnancy, pregnancy toxins, and acute fatty liver of pregnancy are also common causes of elevated aminotransferases.

7. Other infectious diseases, such as pneumonia, typhoid, tuberculosis, infectious mononucleosis, etc.

There are many reasons for a high alanine aminotransferase ratio, so if alanine aminotransferase is elevated, further investigation should be carried out to find out**.

ALT and AST mean alanine aminotransferase and aspartate aminotransferase.

Alanine aminotransferase (ALT) is mainly found in various cells, especially hepatocytes, and the content of transaminotransferase in the whole liver is about 100 times that of the blood. Normally, as long as a small amount is released into the blood, the activity of enzymes in the serum can be significantly increased. Aspartate aminotransferase (AST) is mainly found in the heart muscle, followed by tissues such as the liver, skeletal muscle, and kidneys.

High aminotransferases, first of all, it is caused by life factors, it must be said that drinking alcohol, staying up late and working tired, aspartate aminotransferase elevated, we must try our best to have scheming damage, long-term drinking will lead to alcoholic hepatitis, need to do B ultrasound to further rule out liver cirrhosis, but also to rule out viral hepatitis, steatohepatitis, drug hepatitis, autoimmune hepatitis and so on.

High liver function ALT and AST refer to high alanine aminotransferase and aspartate aminotransferase, which are mainly in hepatocytes, and if the liver is inflamed, hepatocyte necrosis will lead to high levels of these two aminotransferases.

It is recommended to go to the hepatology department or infection department of the hospital to protect the liver as soon as possible**, and the blood is drawn to detect two halves of hepatitis B, hepatitis B virus DNA, and the epigastric color ultrasound or CT is clear. If hepatitis B is not available, it is also necessary to test for hepatitis markers, xenophobia hepatitis C and other viral hepatitis. Hepatitis B is not effective in protecting the liver, and antiviral drugs are usually needed.

Hello, there are many reasons for the elevation of aminotransferases1. When liver cirrhosis and liver cancer cirrhosis are active, aminotransferases are higher than normal levels, and they should be actively **. 2. In the acute attack of cholecystitis and cholelithiasis of biliary tract diseases, fever, abdominal pain, nausea, vomiting, jaundice, elevated blood bilirubin and aminotransferases are common. 3. In the case of acute myocardial infarction, myocarditis and heart failure of heart disease, ALT and AST are both increased, and patients often have chest pain, palpitations, shortness of breath and edema.

Cardiac examination has positive signs and an abnormal ECG. 4. Alanine aminotransferase will also rise in large or long-term drinkers. 5. Viral hepatitis is the most common disease that causes elevated aminotransferases, and all kinds of acute and chronic viral hepatitis can cause elevated aminotransferases.

6. All kinds of drugs and chemical preparations for toxic hepatitis can cause the increase of transaminases, but after the drug is stopped, the transaminases can return to normal. 7. Some other infectious diseases, such as pneumonia, typhoid, tuberculosis, infectious mononucleosis, etc., all have elevated aminotransferases, but these diseases have typical symptoms and can be confirmed with the help of laboratory testing. In addition, acute soft tissue damage, strenuous exercise, and pregnancy may also cause transient elevation of aminotransferases.

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