Is it normal to have 1 1 higher alpha fetoprotein? What diseases are predisposed to cause

Isolated mild elevation of alpha-fetoprotein is not specific and suggests diagnosis in conjunction with clinical and other biochemical indicators.

Fetoprotein can be elevated in serum in about 80% of patients with HCC, and AFP is positive in 50% of germ cell tumors. It can also be elevated in patients with other gastrointestinal tumors, such as pancreatic cancer or lung cancer and liver cirrhosis.

It is also one of the main diagnostic steps in the diagnosis of liver tumors, and of course it is also determined with the help of other relevant tests. The ovaries and adrenal cortex can synthesize cholesterol from acetic acid, or absorb cholesterol from the blood as a substrate to synthesize steroid hormones and secrete them into the blood circulation.

Alpha-fetoprotein (AFP) is a glycoprotein that normally comes mainly from embryonic liver cells, so the amount of alpha-fetoprotein in normal human serum is less than 20 micrograms. Pregnant women and newborns may have a transient increase in alpha-fetoprotein because alpha-fetoprotein is a normal plasma protein component of the fetus, and alpha-fetoprotein may be elevated during pregnancy and gradually return to normal levels after 3 weeks postpartum. However, a high level of alpha-fetoprotein may also mean that the fetus is defective, because when there is a neural tube defect, spina bifida, anencephaly, etc., the alpha-fetoprotein will be significantly high.

High plasma alpha-fetoprotein is diagnostic at 16 to 18 weeks of pregnancy, but it must be combined with clinical experience and ultrasound results to avoid false positive errors.

High alpha-fetoprotein is not a good phenomenon for many people, and it is necessary to pay attention to it, combined with medical history, imaging examinations, etc. to understand the reasons for high alpha-fetoprotein, and reduce the harm caused by alpha-fetoprotein in a timely manner.

Alpha-fetoprotein is a serum protein synthesized by the liver and yolk sac in early fetal life. There are many reasons for high alpha-fetoprotein. For example, benign tumors of the liver, including blood flow, may cause an increase in alpha-fetoprotein if it is relatively large.

There are also primary liver cancers, gonadal embryonic tumors, viral hepatitis, and cirrhosis that can also cause high alpha-fetoprotein, but generally not higher than 400.

It needs to be tested, and patients with abnormal liver function will be accompanied by an increase in AFP, and the increase in AFP accompanied by liver inflammation will gradually return to normal with normal liver function.

Jiangsu Provincial People's Hospital - Department of Infectious Medicine - Chief Physician Li Jun.

I have a high alpha-fetoprotein of 20, what is the reason? I have had multiple hepatic hemangiomas for 8 years, is there a relationship between high alpha-fetoprotein and hepatic hemangioma?

At present, most hospitals use alpha-fetoprotein detection (luminescence method), and a better test is alpha-fetoprotein heteroplasm, which is more accurate than alpha-fetoprotein detection and detects whether liver cancer is obtained, but at present, hospitals have not introduced alpha-fetoprotein heteroplasm.

Alpha-fetoprotein values are high, but the true positive rate is 60%, and 40% are false positives, including people with chronic liver disease and pregnant women.

Everything else is normal, and the values are only a little bit high, so there should be no problem

The reasons for the increase of nail embryo protein can generally be seen: during the period of hepatocyte regeneration, nail embryo protein is positive in the blood, and there will be liver cell regeneration in acute and chronic hepatitis and liver cirrhosis, so the concentration of nail embryo protein in the blood increases, and the nail embryo protein in the blood also increases to varying degrees in some embryonic cancers, germ cell tumors, some digestive tract cancers, etc.;

The common clinical diseases that cause elevated alpha-fetoprotein are:1Liver Cancer:

The positive rate of alpha-fetoprotein in hepatocellular carcinoma was 70 90, and the alpha-fetoprotein measurement value had begun to increase significantly 8 months before the onset of symptoms of hepatocellular carcinoma (alpha-fetoprotein measurement value greater than 500 micrograms for more than 4 weeks; or alpha-fetoprotein can be diagnosed with imaging results when the moderate level of alpha-fetoprotein above 200 micrograms is persisted for more than 8 weeks), so alpha-fetoprotein is the only tumor marker for diagnosing early liver cancer. 2.Chronic Liver Disease Activity:

Alpha-fetoprotein can also be elevated during the active phase of chronic liver disease, but the increase is generally not large, between 50 micrograms and 300 micrograms, and the duration is short. 3.Embryonic carcinoma of the reproductive system:

Alpha-fetoprotein is also elevated in embryonic cancer of the reproductive system.

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Is alpha-fetoprotein high in normal people?

Alpha-fetoprotein is a glycoprotein, abbreviated as AFP. Normally, this protein mainly comes from the liver cells of the embryo, and the alpha-fetoprotein disappears from the blood about two weeks after the fetus is born, so the amount of alpha-fetoprotein in the serum of normal people is less than 20 micrograms.

There are many reasons for high alpha-fetoprotein.