What are the symptoms of glioma?

To tell you the truth, I also have a glioma patient in my family, and he has been feeling headache and vomiting for a while, and he doesn't care about it. But later, it became more and more serious, and his family took him to the hospital, but he didn't expect to be diagnosed with such a serious disease as glioma. Doctors say the main symptoms of the disease are increased intracranial pressure and other general symptoms such as headache, vomiting, vision loss, double vision, seizures and psychiatric symptoms.

The second is the local symptoms caused by the compression, infiltration and destruction of brain tissue by tumors, resulting in neurological loss. Fortunately, my patient was surgically surged**, but the operation is only a foundation**, and the real focus is on**.

I'm not a doctor after all, so I can only give you a general explanation, surgery is to be done, but it is difficult to completely remove glioma stem cells through surgery, so it will be easy**. In other words, it is difficult to avoid, unless you use biological knife technology to remove, which is probably to extract the characteristics of the stem cells of the tumor and then provide them to the "defense cells" in the human body that can kill the tumor cells, so that they can recognize the bad cells and destroy them, which is roughly what it means!

After looking for it, there is only one glioma diagnosis and treatment center in Bayi Brain that can do this glioma biological knife, and there are only a few hospitals in the world that can do it. For other authorities, you can also consult the Center for Translational Neuroscience and the Center for Glioma.

The early symptoms of gliomas are usually subtle and progress at different rates depending on the grade, with symptoms gradually appearing over months or years in low grades, as follows:

1. It usually manifests as headache, nausea, vomiting, and some patients will have epilepsy;

2. Glioma grows near the ** groove of the functional area, and motor and sensory impairments may occur. People with optic nerve gliomas experience visual impairment. Gliomas grow in the language area, and language expression and comprehension can be impaired.

Patients with symptoms such as early morning headache, projectile vomiting, epilepsy, memory impairment or speech impairment are advised to seek medical attention and confirm the diagnosis**.

After the tumor enlarges, the intracranial pressure increases, and symptoms such as headache and vomiting appear. If you only find out at this time, it is relatively difficult and the effect is relatively poor. When it occurs in other functional areas, there may be visual loss, visual field changes, seizures, and unsteady walking.

Gliomas rank first in the incidence of neurological tumors. According to the WHO classification, it is divided into 4 grades: grade I and grade II gliomas have slower cell growth, also known as low-grade gliomas; Grades III and IV, which grow rapidly, are defined as high-grade gliomas.

In recent years, with the development of sequencing technology and big data analysis, the classification of glioma tends to rely more on molecular pathological classification, which has important practical significance for the biological characteristics, best strategies and prognostic judgment of tumors, and is conducive to the development and popularization of personalized diagnosis and treatment.

But today, we still have to start with glioma classification, after all, this classification is relatively mature:

So what is a low-grade glioma?

1.Pilocytic astrocytoma.

The medical term is abbreviated as "Mao Xing", and this subtype specifically targets young people under the age of 25, but it is the slowest and slowest in development, and can be said to be one of the few "malleable talents" in glioma.

2.Diffuse astrocytoma.

The most common low-grade glioma, which tends to occur in people between the ages of 35 and 40, is divided into two subtypes depending on whether there is an IDH gene mutation (more on this later);

3.Oligodendroglioma.

This guy is characterized by both a mutation in IDH and a codeletion of 1p 19q, and the tumor grows very slowly;

4.Gangliocytic glioma.

These rare tumors are mixed with glioma and neuron** tumor components and generally do not grow quickly. In summary, although few of these tumor patients are completely aware, most of them can work, study and live normally and have a high quality of life as long as they actively cooperate and control secondary epilepsy, cerebral edema and related complications.

Absolute demon – high-grade glioma.

Anaplastic astrocytoma.

Anaplastic oligodendrogliomas and anaplastic ependymomas, which are classified as WHO grade III;

Glioblastoma, which belongs to WHO grade IV.

In addition, there are mixed gliomas in which there are two types of tumour cells (oligodendrocytes and astrocytes**): oligodendroastrocytomas (grade II) and anaplastic oligoastrocytomas (grade III).

The symptoms of glioma have some things in common with those of other brain tumors. Symptoms such as headaches, vomiting, and seizures are usually caused first. Therefore, when headache and vomiting occur, it is not immediately judged as a symptom of glioma, but can only be diagnosed through clinical examination and pathological diagnosis.

Let's give you a detailed introduction to the symptoms of glioma.

Symptoms of Glioma:

1. Headache: The first symptom of glioma is headache, which is caused by the compression and involvement of painful and sensitive structures in the skull after the increase in intracranial pressure, such as blood vessels, dura and some cranial nerves.

2. Vomiting: Vomiting occurs when the headache is severe, which is projectile. However, in children, headache may be subtle due to craniosynostomy, especially in posterior fossa glioma, where vomiting is the most pronounced.

3. Epilepsy: Some symptoms of glioma are the first or early main symptom of epilepsy. Brain tumors should be considered if epilepsy begins in adulthood and is not easily controlled by medication or the nature of the seizures is altered.

4. Psychiatric symptoms: Mental abnormalities are symptoms of frontal glioma, which can be manifested as personality changes, apathy, decreased speech and activities, poor concentration, memory loss, lack of care about things, and lack of neatness.

5. Local symptoms: the corresponding symptoms will be produced according to the location of the tumor, and the symptoms will be progressively aggravated. The local symptoms of malignant gliomas are very pronounced and develop rapidly.