What is leukemia and how effective is venetoclax?

Leukemia is a malignant clonal disease of hematopoietic stem cells. Clonal leukemia cells proliferate and accumulate in the bone marrow and other hematopoietic tissues due to mechanisms such as uncontrolled proliferation, impaired differentiation, and blocked apoptosis, and infiltrate other non-hematopoietic tissues and organs, while inhibiting normal hematopoietic function. Clinically, varying degrees of anemia, hemorrhage, infection and fever, liver, spleen, lymphadenopathy, and bone pain may be seen.

There are many ways to achieve leukemia, traditional Chinese medicine, chemotherapy, bone marrow transplantation, cellular immunity, etc., at present, leukemia is not only in hematological remission, should strive to achieve, it is recommended that you can go to the hematology department of a regular hospital Leukemia is divided into three steps, you can consider the combination of traditional Chinese and Western medicine, the first step is to cool the blood and detoxify traditional Chinese medicine with chemotherapy to achieve hematologic remission. The second step is to strengthen the right and dispel evil with traditional Chinese medicine combined with chemotherapy and immunity **** to achieve genetic or molecular biology remission. The third step is to detoxify and dispel evil with traditional Chinese medicine combined with DC-CIK, immunity, etc. to remove microscopic residual leukemia cells.

Leukemia is a malignant tumor of the hematopoietic system. It is manifested by a decrease in normal blood cell production, abnormal quality and quantity of peripheral blood leukocytes, and progressive and uncontrolled abnormal proliferation of leukocytes and their naïve cells (i.e., leukemia cells) in the bone marrow or other hematopoietic tissues, infiltrating and damaging various tissues, resulting in different symptoms.

1. Acute leukemia: the disease develops rapidly, and the bone marrow and surrounding blood are mainly abnormal primitive and naïve cells. The natural history of the disease is usually less than 6 months.

Acute leukemia is divided into: a. acute lymphoblastic leukemia (acute drenching); b. Acute non-lymphoblastic leukemia (acute non-lymphodic leukemia). Including acute myeloid leukemia (acute myeloid leukemia), acute monocytic leukemia (acute monocytosis).

2. Chronic leukemia: the course of the disease is long, and the bone marrow and blood are mainly mature abnormal cells, followed by naïve cells. The natural history of the disease is usually more than one year.

Chronic leukemia mainly includes: chronic myeloid leukemia (chronic myeloid leukemia); chronic lymphocytic leukemia (chronic lymphoma); hirsutical leukemia; Prolymphocytic leukemia.

3. Special types of leukemia: such as hypoproliferative leukemia, green tumor or granulocytic sarcoma, eosinophilic leukemia, basophilic leukemia, etc.

When it comes to leukemia, many people think it's scary, but it's actually because most people don't know much about leukemia. First of all, we need to understand what leukemia is.

Leukemia is a malignant disease of the hematopoietic system, characterized by the widespread and uncontrolled proliferation of a large number of leukemia cells in the body, appearing in the bone marrow and many other organs and tissues, and entering the peripheral bloodstream. Acute leukemia has a rapid onset, rapid progression, and a dangerous condition, which seriously endangers human health. With the progress of medicine, acute leukemia has been positive, most patients can achieve remission, and now the alleviation of leukemia is no longer the ultimate goal, how to improve the rate, so that most leukemia patients can get the most of the leukemia patients, has become the focus of today's hematology research.

From a large number of clinical practices, the early involvement of targeted drugs in leukemia** can significantly improve the condition of patients. Studies in the modernization of traditional Chinese medicine for leukemia have shown that the targeted drug venetoclax can effectively inhibit the proliferation of HL-60 cells, and the inhibitory effect is concentration-dependent, which has a relatively definite effect on leukemia.

The targeted drug venetoclax is used for leukemia**, and each patient's condition is different, so it is recommended to consult a doctor directly. Not yet in China, Hong Kong and Hong Kong have been listed.

Summary. Acute myeloid leukemia is a malignant clonal disease of myeloid hematopoietic stem and progenitor cells, characterized by abnormal proliferation of blasts and naïve cells in the bone marrow and peripheral blood. Its clinical manifestations can include anemia, hemorrhage, infection, fever, cold intolerance, infiltration of various organs and metabolic abnormalities of the whole body.

Among the drugs currently available for leukemia** is venetoclax.

In December 2020, it was officially approved for marketing in China, and many patients were also the first to learn the news and were excited. The official approval of venetoclax also means that domestic patients can successfully buy venetoclax in major hospitals, benefiting more domestic patients.

**In terms of efficacy, venetoclax is a BCL-2 inhibitor. BLC-2 is the "survival protein" that cancer cells rely on to survive and multiply. Venetoclax destroys cancer cells by attacking BCL-2, and venetoclax can effectively inhibit the function of BCL-2 when used as a single drug.

What are the effects of venetoclax** in acute myeloid leukemia? **Can it be bought?

Acute myeloid leukemia is a malignant clonal disease of myeloid hematopoietic stem cells and progenitor cells, which is characterized by the proliferation of blasts and naïve cells in the bone marrow and peripheral blood. Its clinical manifestations can include anemia, hemorrhage, infection, fever, cold intolerance, infiltration of various organs and metabolic abnormalities of the whole body. Among the drugs currently available for leukemia** is venetoclax.

In December 2020, it was officially approved for marketing in China, and many patients were also the first to learn the news and were excited. The official approval of venetoclax also means that domestic patients can successfully buy venetoclax in major hospitals, benefiting more domestic patients. **In terms of efficacy, venetoclax is a BCL-2 inhibitor.

BLC-2 is the "survival protein" that cancer cells rely on for survival and nuclear modification of potato reproduction. Venetoclax destroys cancer cells by attacking BCL-2, and venetoclax can effectively inhibit the function of BCL-2 when used as a single drug.

It's safer to go to JD.com to buy it.

What are the methods of leukemia**, which can only give you the right symptoms according to the symptoms of your leukemia**.

Leukemia is a serious disease caused by malignant clones of hematopoietic stem cells. In terms of current medicine, there are many causes and causes of leukemia in humans, so it is not completely clear. Leukemia is very harmful to people, leukemia can cause normal human tissue failure, and even lead to death.

The methods of leukemia include drugs, radiotherapy, and comprehensiveness.

Leukemia is a disease that is dreaded in everyday life. Because leukemia has a very large adverse effect on people. Moreover, it will cause gradual problems in various body organs of the patient, and even functional failure. In severe cases, death may even occur.

1. Drugs.

The characteristics of the patient's leukemia are judged by the doctor's diagnosis, and the drug is selected. The drug must be carried out in strict accordance with the course of treatment arranged by the attending doctor, so as to ensure that the drug can have a significant effect on leukemia. Moreover, how long the maintenance of the drug needs to last in the later stage needs to be decided according to the specific situation of the patient's body.

Therefore, the ** of leukemia drugs cannot be arranged by yourself, and the dosage or lack or addition will be affected, so you must follow the doctor's instructions.

2. Radiotherapy**.

Radiotherapy is also the most chosen method for leukemia patients. For different situations and different types of leukemia, it is necessary to choose different methods of radiochemical treatment, such as AML and so on. Radiotherapy is a common method, which can effectively control leukemia and effectively relieve the symptoms and conditions of leukemia.

Therefore, radiotherapy can also be selected in the method of leukemia.

3. Comprehensive.

There are many methods and means of comprehensiveness, and the aspects involved are also very extensive. It can provide a more scientific effect on leukemia. Under normal circumstances, the ** of leukemia can be effectively improved, and a very large number of patients can control the long-term stability of the disease through comprehensive **.

If the condition is mild, it can even achieve the effect of **.

Leukemia**: 1. Genetic factors. Leukemia is hereditary, but it is not a hereditary disease.

You may be a little confused when I say that I mean that there are other genetic diseases in the family, such as congenital aplastic anemia with multiple malformations, congenital distal telangiectasia erythema, and severe combined immunodeficiency. These genetic diseases are responsible for the higher incidence of leukemia than in the general population. In addition, if one of the identical twins has acute leukemia, the other has a 20% chance of developing leukemia, which is 12 times higher than that of dizygotic twins.

The main cause is chromosomal breakage, lithic fissure, and translocation, resulting in changes in the location of proto-oncogenes or activation leading to food activity of tumor suppressor genes.

2. Environmental pollution. The main cause of leukemia caused by environmental pollution is a chemical element "benzene", which causes genetic mutations in hematopoietic stem cells, resulting in leukemia. The main sources of pollution are paints containing benzene in construction sites and interior decoration, household gas, and hair dyes containing aniline, all of which may cause leukemia.

3. Viruses. T-lymphocytic leukemia is a rare, specific type of lymphocytic leukemia. Retroviruses of RNA viruses can cause this type of leukemia.

4. Blood diseases. Blood diseases such as polycythemia vera, essential thrombocythemia, and myelodysplastic syndrome may cause acute leukemia, and patients with blood diseases must actively carry out it in a timely manner to avoid the risk of leukemia.

5. Radioactive factors. One or more doses of radiation may cause leukemia, resulting in bone marrow suppression, reduced immunity, and chromosomal breakage.