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Who said that metformin hurts the kidneys??? I have been practicing medicine for 20 years, and I first started to use metformin for patients in 1995, when the beta melon had not been withdrawn from the market, and I had repeatedly checked the information and did not say that it hurt the kidneys, at that time, a box of 48 tablets of metformin was 56 yuan. It is much more expensive than now, and with the increase in the number of diabetic patients and the increase in patients taking metformin, I don't know when it was said that metformin hurts the kidneys.
So far, there is no evidence to prove that this drug hurts the kidneys, and I personally think that it is mainly due to the conclusion that most patients see the instructions and say: Renal insufficiency should be taken with caution. View the original post
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Do you need to tonify your kidney? Metformin is cheap and expensive, and I have only heard that cheap ones hurt the kidneys. One of my classmates was a doctor in the endocrinology department of the hospital, and when I went to see him for diabetes, he prescribed me expensive ones, and said that cheap ones hurt my kidneys. View the original post
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Today I met a sugar friend again, she took Chinese medicine, she felt that the effect was not good, it was quite expensive, I wanted to change the medicine, asked me what to eat, I said I take metformin, she read the instructions and said that metformin is *** big, don't eat, I think it seems to be a medicine for diabetes ***, I used to eat An Lize when the instructions also took a lot. View the original post
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Metformin has been clinically proven to be safe for many years, otherwise the Chinese Type 2 diabetes guidelines would not have listed metformin as the first choice of drugs. View the original post
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You also need to replenish your kidneys if you eat Erjia View the original post
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I heard an old Chinese medicine doctor say that he wanted to eat some Liuwei Dihuang pills! The main reason is not that Dimethyl is not good for the kidneys, but that Chinese men generally have kidney deficiency, especially with age, the function of the kidneys weakens, and Dimethyl is mainly decomposed by the kidneys and excreted from the body, so there is no harm in supplementing the kidneys! People who are not sick still need to replenish their kidneys, not to mention what about us View the original post
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Metformin should be taken at the right time and dosage, it is better to eat before and after meals, not to overdose, listen to the doctor's guidance when adjusting the dosage, and at the same time need to pay attention not to take it blindly, if there is an uncomfortable reaction, be sure to stop the medication in time.
How to eat metformin is the right one?
Metformin can help diabetics stabilize blood sugar, and the damage to the body is relatively small, we should also master the correct method when eating in life, so as not to cause some *** to the body, the time of hypoglycemic drugs must be selected correctly, if the hypoglycemic effect is not obvious, do not blindly increase the dosage yourself, you must make some adjustments according to the doctor's guidance, it is better to take it in the morning, and it is better to take it before meals, because it may cause discomfort to the spleen and stomach, so it is better to eat before and after meals, The effect is more pronounced before meals. When we take medicine, we must choose a reasonable time, and if there is any problem, we must ask the doctor in time.
What should we pay attention to?
The dosage of metformin should be based on the patient's blood sugar level and the usual situation, according to the physical reasons to formulate a scientific medication time and dosage, blood sugar control is stable and the dosage should be adjusted in time, at the same time, it is necessary to pay attention to the appropriate physical exercise in taking the drug, and the diet should be controlled to a certain extent, in order to have a better effect, do not take blindly when taking medicine, take it scientifically under the guidance of a doctor, if there is gastrointestinal discomfort and nausea and vomiting on the body, you must consult a doctor in time, In short, you must be cautious when taking medication and listen to the doctor's guidance.
It can be seen from this that you must strictly listen to the doctor's guidance when taking metformin, you must listen to the doctor when adjusting the dosage, do not blindly increase or decrease the dosage, and at the same time pay attention to stabilizing your blood sugar in life, and carry out scientific physical exercise, so as to achieve better results.
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Metformin itself has no liver and kidney toxicity, but only 90% is excreted from the kidneys, and if renal insufficiency will hinder the discharge of the drug, resulting in the accumulation of the drug in the body, and there is a risk of inducing lactic acidosis.
Proteinuria and renal insufficiency in diabetic patients are often complications caused by long-term hyperglycemia, which is not in place for you, but will be thought to be caused by metformin by some sugar friends.
Metformin can be used safely as long as liver function does not exceed 3 times the upper limit of normal (eg, aminotransferase 120u L).
Renal function is measured by the serum creatinine index EGFR (estimated glomerular filtration rate), and the metformin dose is reduced only when the EGFR is significantly reduced by <60 mL and discontinued when the EGFR is < 45 mL.
The adverse reactions of metformin that can often be seen in clinical practice are gastrointestinal discomfort (5%), including nausea, stomach distention, diarrhea, etc., which can be started with a small dose (500mg daily) and gradually increased, and the vast majority of patients will gradually tolerate it after a few weeks, and the symptoms will disappear.
Long-term use of metformin may cause a decrease in vitamin B12 levels, and it is recommended to supplement vitamin B12 appropriately for this group of people.
During diabetic ketosis, metformin should not be taken before or after the use of contrast agents and in cases of severe cardiopulmonary insufficiency to avoid lactic acid poisoning.
It is recommended not to self-administer the medication, if necessary, please go to the outpatient clinic and make a comprehensive judgment before taking the medication.
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Because patients with renal insufficiency cannot take metformin, many people think that metformin hurts the kidneys, but in fact, this does not mean that metformin hurts the kidneys.
The latest expert consensus on the clinical application of metformin in China points out that metformin has good safety and tolerability, low incidence of hypoglycemia, does not cause kidney damage, and long-term use does not increase the risk of hyperlactic acidemia or lactic acidosis. Estimated glomerular filtration rate (EGFR) 60ml min, no need to adjust the dose, rest assured; EGFR45 60ml min should be used in a reduced dose; EGFR<45ml min should be contraindicated.
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If you take it in small amounts, it may not, but if you take it regularly, it maybe.
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The kidneys are important organs for drug excretion, and drug-induced kidney injury refers to the adverse reaction of the kidneys to the dose of drugs. Or due to drug overdose or unreasonable application, some toxicity is produced, and then it is commonly known as kidney injury. Most of metformin is excreted in urine from the kidneys in its original form.
Cleaning is quick. It doesn't do much harm to the kidneys. The instructions for biplus biguanide also do not say that there are adverse effects on the kidneys.
It shows that there is no nephrotoxicity in the test, and there are no reports of metformin harming the kidneys in the follow-up after the drug is marketed.
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The problem is this, the hypoglycemic drug metformin itself has no liver and kidney toxicity, 90% can be excreted from the kidneys, and will not harm the kidneys. However, if the kidney is insufficient, it will hinder the discharge of drugs, resulting in the accumulation of drugs in the body and damage the kidneys, and some even acidosis. Therefore, you should follow your doctor's advice when taking metformin to avoid danger.
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The kidneys are used to detoxify, and it will definitely filter out some of the things we need, which will undoubtedly increase the burden on the kidneys.
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Metformin has a significant hypoglycemic effect and is a more effective hypoglycemic drug, but many patients have doubts about whether metformin hurts the kidneys. Metformin is excreted in the kidneys as a prototype with no damage to the kidneys, and there are reliable studies showing that metformin has a protective effect on the kidneys. The 2018 diabetes guidelines proposed that patients with mild impairment of renal function do not need to reduce the dose of biguanide, and only patients with moderate to severe renal impairment need to reduce or stop the dose.
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Taking it for a short time will not hurt the kidneys, but after a long time, it will definitely have an impact on the kidneys. Especially people with renal insufficiency.
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Does taking metformin hurt the kidneys, 90% of metformin is excreted from the kidneys, so long-term use of metformin is still toxic to the kidneys.
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If you take it for a long time, it will definitely have an effect on the kidneys, so it is recommended to listen to it after taking it for a while.
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Metformin. This medicine is a must for diabetics, he helps with detoxification. Diuretic, hypoglycemic. However, eating for a long time will also hurt the kidneys and liver, so it is better to strengthen physical exercise.
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Metformin does not hurt the kidneys, and the Chinese diabetes guidelines have repeatedly used this drug as the preferred drug for type 2 diabetes, and this drug has been safely used for more than 70 years.
In diabetic patients with normal kidney function, the application does not cause any damage to the kidneys. However, folklore often says that metformin hurts the kidneys, and this situation is because the patient did not get a regular ** in the early stage.
Chronic renal insufficiency has already occurred, and then taking metformin, this condition is not good for the kidneys. Early use of metformin in diabetic patients is very safe.
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What about taking metforma? There may not be any big problems in the short term, but if you take it for a long time and the dosage is relatively large, it will indeed hurt the kidneys. Because it is difficult to excrete from the body.
At this time, there will be some precipitation in the kidneys, so of course there will be a possibility of kidney damage.
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Taking metformin does not harm the kidneys. Because metformin is not residual in the body, it is basically metabolized. But if the kidney disease is severe. There is a problem with metabolism. Metformin should be taken under the guidance of a doctor.
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It is a medicine that is three parts poisonous, and taking metformin will hurt the kidneys.
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Taking metformin itself does not harm the kidneys. Because 90% of it can be metabolized normally. However, if the nephrotic syndrome is severe, the dosage should be adjusted, otherwise it will also cause kidney damage.
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Will taking metformin hurt my kidneys? Metformin can hurt the kidneys. If you take too much medicine, it will hurt your kidneys.
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The drug is originally for diabetes, so it is necessary to check the patient's kidney function before taking it, and stop taking the drug when the patient is taking it or has adverse reactions.
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Metformin has an effect on the kidneys, which means that the writing is very clear, so it is necessary to read it and use it with caution.
Most of the oral hypoglycemic drugs such as metformin, glipizide, and glibenclamide, which are commonly used in diabetes, will cause some damage to the liver, so the medication regimen for diabetic patients will increase liver protection**. That is, while taking hypoglycemic drugs, add hepatoprotective drugs such as liver protection tablets to prevent the damage of hypoglycemic drugs to the liver, and also have a certain synergistic effect on diabetes, because diabetes itself will induce fatty liver and worsen liver function.
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It may be that metformin causes symptoms of vomiting and diarrhea, and now you have a loss of appetite and your mental condition is not as good as before taking the drug, you can stop the drug and change to other oral drugs. If this is not possible, insulin can also be used under the guidance of a local doctor.