What exactly is the difference between Ghuazhi and regular metformin? 20

The differences between Gehuazhi and metformin are as follows:

1. The forms of the two are different.

The main ingredient of Gehuazhi is metformin hydrochloride, which is a film-coated tablet that appears white after removing the coating.

Metformin is its hydrochloride, which is a white crystalline or crystalline powder; Odorless. Soluble in water, soluble in methanol, slightly soluble in ethanol, insoluble in chloroform or ether.

2. The pharmacology of the two is different.

Hypoglycemia did not occur even with metformin at a dose of 85 g, but lactic acidosis occurred in this case. Under good hemodynamic conditions, metformin can be cleared by dialysis at a rate of 170 ml. Thus, in patients with suspected metformin overdose, hemodialysis can remove the accumulated drug.

Metformin is a biguanide oral hypoglycemic drug, and its effect is weaker than phenformin. The absorption rate is only 50%. Tmax is about 2 hours and does not bind to plasma proteins in plasma.

Almost all of them are excreted by urine, the first phase T1 2 is about 3 hours, the second phase T1 2 is about 12 14 hours, and the hypoglycemic effect can last for 8 hours.

3. The dosage of the two is different.

The dosage course of Gehuazhi is grams; or grams; Grams can be increased weekly, or incrementally to 2 grams over 2 weeks.

Metformin is available in tablets, capsules, enteric-coated (tablets, capsules) in slightly smaller doses.

There is a difference, metformin has a general effect.

Different manufacturers are different.

There are about a dozen pharmaceutical factories producing metformin sustained-release tablets in China, and the metformin sustained-release tablets produced by each pharmaceutical factory have their own trade names, so each pharmaceutical factory will vigorously promote its own products, and there must be fierce market competition.

When **is suppressed to below the cost**, then the quality of the drug may not be guaranteed, therefore, we should try to choose metformin sustained-release tablets produced by well-known pharmaceutical companies, even if it is slightly expensive, it is also guaranteed by quality.

In short, metformin sustained-release tablets are the first choice for type 2 diabetes mellitus, there are many manufacturers in China, ** is different, we should first look at the packaging specifications of the drug when choosing, the packaging specifications are different, it can not be compared**.

Metformin sustained-release tablets are the selected varieties in the second round of "4+7" national centralized procurement, and the price will be reduced, and soon everyone will be able to buy metformin sustained-release tablets with the highest quality and efficacy.

Metformin is a biguanide oral hypoglycemic drug, which has been recommended as a first-line hypoglycemic drug by many guidelines at home and abroad. It has more than 20 years of clinical application experience in China, and is currently one of the most widely used oral hypoglycemic drugs in the world.

However, metformin has been developed so far, and it is divided into many types: ordinary tablets, enteric-coated tablets, sustained-release tablets, and controlled-release tablets, that is, sustained-release tablets ( ) Different types represent the development and progress of science and technology.

Ordinary tablets may need to be taken three times a day, but sustained-release tablets ( ) only need to be taken once a day to control sugar smoothly, and the best time to take them varies depending on the medicine. Metformin is best taken after a meal.

When I was discharged from the hospital, my attending physician told me to use Gehuazhi for double melons, and I didn't ask me to buy it at **, so don't always be worried about the doctor. View the original post

Gehuazhi has high purity and advanced molding technology. Although the ingredients are the same, there may be some differences in long-term use. View the original post

Gehua is good, after all, it is to be taken for a long time, the process control of large enterprises is strict, and all indicators have reached the level of refinement, although the products of small enterprises can meet the standards, but the domestic standards are very flexible. View the original post

Hello, I am glad to answer for you: it is not recommended to mix and eat, because the ingredients of metformin and metformin sustained-release tablets are not the same, and their effects are different, and mixed eating may affect the efficacy of the drug, and even cause adverse reactions. Therefore, it is recommended that patients take the dosage according to the dosage of the liquid in the drug instructions under the guidance of the doctor, so as not to affect the efficacy.

In addition, patients should also abide by the doctor's instructions, review regularly, and adjust the use of burning and occult drugs in time to ensure the best effect.

Gehuazhi is a foreign drug, and it may work a little better, but it doesn't make much difference.

Hello, Gehuazhi is suitable for patients who are fatter because of the larger dose.

But you can also break one piece of Gehua into 2 halves and take it, no problem.

Sustained-release tablets decompose slowly, absorb slowly, and have a long-lasting effect. If it is high simply after a meal, it is recommended to eat acarbose or change back to Gehuazhi.

The main ingredient of metformin sustained-release tablets and Gehuazhi is metformin hydrochloride, which is one of the oral hypoglycemic drugs with the best hypoglycemic effect of single drug, and its main difference is that the dosage form is different, metformin hydrochloride sustained-release tablets are sustained-release tablets, and Gehuazhi is an ordinary tablet. The second is the difference in the number of times you take it per day, which leads to the difference in the cost of taking the drug per day.

Metformin sustained-release tablets and Gehuazhi, please strictly follow the drug instructions and the doctor's prescription! Due to seasonal, regional and other reasons, metformin sustained-release tablets and Gehuazhi** may fluctuate to a certain extent, but the fluctuation is not large. Metformin extended-release tablets and Gehuazhi specific ** toCardinal Health's PharmacyAll branches nationwide shall prevail!

Answer: The effect of Gehuazhi and metformin extended-release tablets will be better relatively speaking. The absorption speed of Gehuazhi is very fast, and the effect is also very fast. The decomposition of metformin and double arc sustained-release tablets is particularly slow, but it can control blood concentration well for a long time.

Therefore, when patients use drugs, they should also follow the doctor's instructions, and then choose drugs according to their own conditions, so as to effectively control the development of the disease. Patients must not consume too much sugar during the use of the drug, and need to visit the hospital regularly for physical examinations.

Then it seems that I still don't fit into this, so let's switch back to Gehuazhi. So if you say three tablets a day, in addition to having an effect on post-meals, does it have the effect of reducing fasting? View the original post

Pay attention to taking Metformin Hydrochloride Tablets: 1. During the oral administration of this product, regular examination of kidney function can reduce the occurrence of lactic acidosis, especially for elderly patients. Before undergoing surgery and iodine X-ray examination, patients should stop oral administration of this product.

2. Poor liver function: some patients with lactic acid poisoning have liver damage, so people with liver disease should avoid using this product. 3. Stress state:

In the case of fever, coma, infection and surgery, patients taking oral hypoglycemic drugs are prone to temporary poor blood sugar control, and the main product must be stopped and insulin used instead. Resume use after the stress state has resolved. 4. For patients with type 1 diabetes, this product should not be used alone, but should be combined with insulin.

5. If patients with type 2 diabetes mellitus with good blood sugar control have laboratory abnormalities or clinical abnormalities (especially fatigue or indescribable discomfort), they should quickly look for evidence of ketoacidosis or lactic acidosis, and measure serum electrolytes, ketones, blood glucose, blood pH, lactate, pyruvate and metformin levels. 6. Patients who receive metformin hydrochloride tablets alone** will not have hypoglycemia under normal circumstances, but when they eat too little, or do not supplement enough calories after exercising, they will have hypoglycemia when they are used in combination with other hypoglycemic drugs (such as sulfonylureas and insulin), and when they drink alcohol, they should be noted. 7. Elderly, frail or malnourished patients, as well as patients with low adrenal and pituitary gland function, and alcoholism are more likely to develop hypoglycemia.

Hypoglycemia in older patients and those taking -adrenal blockers is difficult to identify and should be noted.