Is Ansu Meng Water Agent safe? Which is better, Ansu Meng or Kinsey s water agent

Since 1985, when the FDA approved the first indication of growth hormone: growth hormone deficiency, growth hormone has been used for more than 30 years. Ansumeng and Kinsey are both old brands of domestic growth hormone.

Kinsey's water agent was listed earlier, the common specification is 30IU per stick, children should use growth hormone as a purpose to improve height, and the single-day dose is mostly 3-10 units per day, obviously the packaging of 30IU can not be used up in a day, due to the early listing and technical limitations, phenol can only be added as a bacteriostatic agent to prevent multiple punctures from affecting the quality and effect of the drug caused by microorganisms. Ansumeng's water agent was newly launched in 2019, and it took more than ten years to overcome technical barriers, without adding phenol or m-cresol and other bacteriostatic preservatives, using 1 stick a day, ready to use and throwing, safer and more effective, and more suitable for children to use for a long time. The first course of growth hormone treatment is long, and some children with idiopathic short stature need to be intervened until adulthood is high for life, and parents should pay more attention to the safety of drugs for long-term use!

Ansumeng growth hormone is the first growth hormone approved for idiopathic short stature indication in China.

Ansumeng has a water agent, which was listed in 2019, and is currently the drug with the most complete clinical indications, and it is also the only growth hormone water agent that does not add preservatives At present, the growth hormone water used on the market is the growth hormone declared and produced by the technology many years ago, and the manufacturer is limited by the production process at that time, and can only ensure that the drug is not contaminated by adding preservatives. In recent years, the country's requirements for drug safety have gradually improved, following the international design trend of preservative products, following the guiding ideology of children's drug use of the domestic Food and Drug Administration, advocating the use of preservative-free drugs. Compared with the first generation of preservative-containing growth hormone water, the safety of Ansumeng prefiller has been upgraded, so we say that Ansumeng is a new second-generation growth hormone water.

To put it simply, Ansu Meng Water Agent is the first generation of growth hormone production technology on the basis of safety upgrade, is currently the world's only preservative-free growth hormone water agent, is the world's safest growth hormone water agent, to ensure the safety and effectiveness of Ansu Meng Water Agent, so we say that Ansu Meng Water Agent is a new second generation of growth hormone water agent.

Yes, in order to prevent the injection from being contaminated by bacteria, as well as to prolong the storage time of the drug, phenol is usually used as a preservative for preservative, phenol has the effect of inhibiting bacteria, but also a toxic substance, genotoxicity and neurotoxicity, and will also bring damage to liver and kidney function.

1. Ansu Meng Water is the only growth hormone water agent in the world that does not contain preservatives, which can avoid the risk of damage to children's central nervous system, liver and kidney caused by long-term injection of preservatives, and it is safer for children to use it for a long time.

2. Ansu Meng Water Agent is the second generation of growth hormone water agent, which adopts international leading biotechnology and breakthrough innovative biotechnology to fully maintain the natural structure of protein and have better long-term drug efficacy.

3. The Ansu Meng water agent approved by Anke Biotech this time is pre-filled and packaged, simplifying the injection process, eliminating the need to replace needles, making the operation more convenient and reducing the risk of being stabbed during the dispensing process. The advent of a new generation of growth hormone aqueous agent also provides a safer choice for clinicians and patients. Therefore, from the perspective of safety, it is better to choose preservative-free growth hormone to ensure the safety of children's medication.

Ansu Meng has a water agent, which is a new second-generation growth hormone water agent, using the latest prefilled dosage form, and is the only water agent in the world that does not contain preservatives. It effectively avoids the risks of germ cell DNA damage, central nervous system and liver and kidney function damage caused by long-term use of drugs containing phenol preservatives, ensures clinical safety, and is more suitable for long-term use of children. Ansu Meng Water is currently the only growth hormone approved for ISS indications in China, and the instructions specify the ISS indications to ensure the safety of clinical prescription.

Ansumeng and Saizeng are the two kinds of growth hormones that are currently used more, and the specific activity of Ansumeng powder is higher than the national standard and meets the European standard. Kinsey powder varies in specific activity. What is the difference between Ansu Meng Water Agent and Kinsey Water Agent?

Specifically, there are the following points: Ansumeng pre-filled water agent is the world's latest generation, the only preservative-free growth hormone water agent, compared with Kinsey card bottle water agent, it has the following three advantages: first.

1. It does not contain preservatives such as phenol, which is safer. Because the Kinsey card bottle water agent needs to be injected multiple times, the liquid medicine will be exposed to the air, in order to avoid bacterial contamination, phenol is added to the Kinsey water solution as a preservative and bacteriostatic agent. Although its phenol content is 3mg ml, which is lower than the national requirement of 5mg ml, there has been a number of evidence that phenol can damage cell chromosomes and DNA after accumulation in the human body, and is genotoxic, so American scientists advocate the production of preservative-free single-dose biological agents.

Ansumeng pre-filled is a single-dose biologic, no contact with air, no need to add phenol, and it is also the only preservative-free growth hormone water in the world, which is safer to use. Clause.

Second, there is no repeated puncture to avoid drug contamination. For Kinseyka-type bottle water agent, patients need to repeatedly take and puncture the rubber stopper site 10-20 times during the use process, and it is very easy for the rubber stopper particles to fall off into the liquid medicine and contaminate the solution. Clause.

3. Extremely simplified operation and more convenient. Ansumeng prefillable injection only requires one step, and can be injected directly after disinfection, and Kinsey's cartridge needs to be injected after additional needle extraction. The operation has been simplified to the extreme, which is greatly convenient for children to use. Clause.

4. As we all know, safety is the most concerned factor for clinicians and parents, especially the safety of drugs in children's medication is more important. Growth hormone is used in pediatrics as a long-term process, and the accumulation of phenol poses risks to children's reproductive and nervous systems. Long-term use of drugs with phenol preservatives may cause DNA damage to the patient's germ cells, central nervous system, liver and kidney, etc., so it does not mean that there is a risk, but there is a risk.

Therefore, to avoid the risk of occurring, we recommend using a water agent that does not contain phenol preservatives, like canned fruit and fresh fruit, if you had to choose for your child, which one would you choose?

Specific activity refers to the unit of biological activity per milligram of protein, which is an important indicator that recombinant protein drugs differ from chemical drugs.

The detection of specific activity items can not only reflect the stability of the product production process, but also compare the quality of the same product produced by different expression systems and different manufacturers. High specific activity indicates that the production process of the product is more advanced, the purity is higher, and the quality is better.

Before 1993, the determination of the specific activity was determined by animal experiments, and the error was very large, and a certain amount of finished growth hormone products could not correspond to the fixed activity, and the activity could only be measured by the international unit IU. With the improvement of genetic engineering technology, a certain amount of finished growth hormone can correspond to a fixed activity, and the quantitative determination is more accurate, so the international stipulation in 1993 is to use the content (mg) to measure the activity. All products of Ansumeng are specific to the activity, and the technical process contains Li Bei and is stable.

is the most reliable growth hormone.

Comparison of Saizeng and Ansu Meng water agent.

In terms of ingredients, specific activity, indications, product specifications, and operation, parents need to carefully compare and use safer and more secure products for their children.

1. Ingredients: As medicines, in addition to the main ingredients such as "human growth hormone", Ansumeng and Saizeng have added some necessary excipient ingredients, such as histidine, poloxamer 188, mannitol, and water for injection.

In addition, Sayzeng's excipients are additionally added with glycerin and phenol preservatives. Because Saizeng was listed earlier, the technology and process were limited, and preservatives needed to be added to prevent deterioration, Ansumeng, as the preferred brand of powder and the new second-generation brand of water agent, was listed slightly later, so the product technology and process are more advanced, no preservatives need to be added, the ingredients are safe, and it is suitable for long-term use by children.

Phenol is highly toxic, cytotoxic and genotoxic, but can bring damage to the central nervous system and liver and kidney to patients, parents must pay more attention.

2. Specific activity.

Specific activity is an important indicator to test the production technology, purity and efficacy of the product, according to the calculation of the drug instructions, Ansumeng powder and water have achieved the specific activity, the efficacy is better, and the use is more assured; The water enhancer only has the specific activity achieved by the water agent.

3. Indications.

There are many kinds of short stature in children, and the doctor will choose the right growth hormone according to the ** after the diagnosis of the examination, and only Ansumeng has reached the most complete spring calendar 8 indications, and other brands of growth hormone have not been qualified.

4. Product specifications.

We all know that the dosage of each child is different, and growth hormone must be administered by the doctor according to the actual situation of the child, and the parents should complete the injection at home. At this time, which brand of drug has more specifications can provide doctors with more accurate dispensing guidance, provide parents with a more convenient use experience, and reduce the risk of drug waste and contamination. Ansu Meng Water Agent has these four specifications.

At present, Kinsey's water agent for children** is only 30 units, and parents have very little choice.

To sum up, choosing Ansumeng is safer, more convenient, and more effective!!

For parents who need to use growth hormone for a long time to help improve their child's height, it is not a problem to cooperate with the doctor to conduct a series of examinations for their children in the early stage, but the most difficult thing is to decide which growth hormone to choose. There are two brands to choose from, Saizeng and Ansumeng, both of which have many drug groups.

In contrast, Ansu Meng's water agent has more advantages, first of all, the ingredient Sai water enhancer adds a certain concentration of preservatives in accordance with national standards from the perspective of drug safety. However, Ansumeng's water agent does not add preservatives, fully maintains the natural structure of the protein, and adopts pre-filled packaging to simplify the injection process, without dispensing and replacing needles, which is safe and effective.

The second is the specific activity of the drug, the specific activity is the unit of biological activity per milligram of protein, which is an important indicator to test the production technology, purity and efficacy of the product. Ansumeng drug is more active than reached, so it has a fast onset of action and better efficacy.

The third is adaptability, growth hormone is used as a prescription drug, and the use needs to strictly follow the indications, and under the diagnosis of a professional doctor, the use of the premise of excluding contraindications should be standardized. Idiopathic short stature: At present, only Ansumeng's water agent in China has this indication.

The fourth is the product specifications, the dosage of each child is not the same, growth hormone must be guided by a professional doctor according to the actual situation of the child, and parents can complete the injection at home. The diversification of product specifications provides certain convenience for different needs to a certain extent. According to the different doses of the child to use the adapted specifications, if the single dose is insufficient or the single bottle is not used up, the excess potion can be eliminated, and the mountain can effectively eliminate the production of bacteria.

In this way, the advantages of Ansu Meng Water Agent come out, and you can choose Ansu Meng Water Agent with confidence.