What are the therapeutic mechanisms and indications of DC cell therapy for cancer?

There are many types of cellular immunity**, and dendritic cells are one of the most effective**, and these cells have an antigen-presenting function when viruses or bacteria invade the body, or when cancer cells occur, these substances are considered foreign substances. It is then ingested and broken down on its own, and part of it is used as an antigen (a marker for foreign substances) to transmit marker messages to the cell surface. Although antigen-presenting functional cells other than dendritic cells are also present, they are less than one percent of dendritic cells.

Because dendritic cells are the most effective at presenting antigens, they are also known as the "towers of the immune system."

Japanese dendritic cells** are the ones that make use of the excellent antigen presentation function of dendritic cells**. Dendritic cells play a role in providing T cells with information about cancer antigens (cancer markers) that attack targets. After receiving the cancer antigen information, the T cells attack this cancer cell in a precise manner.

For patients who are unfortunate enough to suffer from cancer, if they have indeed completed the standard**, they can consider dendritic cells** in Japan to prevent it**. However, the hospital needs to do a comprehensive analysis and evaluation of the patient's disease, analyze whether the patient is suitable for this kind of **, and judge whether to accept the patient**. Now there are special agencies to contact for assessment, such as Adventist Health.

Hope you find this helpful.

DC cells.

COPY, also known as dendritic cells (DC), is the most functional full-time DU antigen presenting cell.

Antigen Presenting Cells (APCs), which can efficiently uptake, process, and present antigens, immature DCs have strong migration ability, and mature DCs can effectively activate naïve T cells, which are at the center of initiating, regulating, and maintaining immune responses. DCs are closely related to the occurrence and development of tumors, and the prognosis of patients with a large number of DCs with invasive intra-tumor invasion in most solid tumors is good. The core of an effective anti-tumor immune response is to generate a cellular immune response dominated by CD8+ T cells, which is also the basis of DC as an immunological means.

Elie Gilpowa, director of research at Duke University's Center for Genetics and Cytology, said: "DC is one of the most effective ways to stimulate the body's immune system to fight off cancer. "DCs, as highly specialized primary antigen-presenting cells, play a key role in inducing highly efficient and specific T-cell immune responses against relevant antigens.

International Oncology Center, 309 Hospital.

DC cells, also known as dendritic BAI cells, are the most functional full-time antigen transmitters in the body

Mature DCs have strong migration ability, and mature DCs can effectively activate naïve T cells, which are at the center of initiating, regulating and maintaining immune responses.

To add a little bit, the English name is dendritic cell, although the name is reminiscent of the dendrites of nerve cells, but it actually belongs to the immune system

Both DC and CIK cells are important immune cells in the human body that can help the body fight off external invasions. The tumor progresses very slowly at the beginning of the disease, because the human body is constantly fighting against the tumor, once the body's immunity is at a downbeat, the tumor will lose control and grow rapidly.

The principle of DC-CIK** is that DC and CIK cells are isolated from the patient's body and expanded and cultured in vitro (the growth of the patient's own DC and CIK cells is inhibited due to the effect of the tumor). After reaching a certain amount, it will be infused into the patient's body, which is equivalent to artificially enhancing immunity.

However, at present, the indications of DC-CIK** are not very clear, and there are very good efficacy, but there are also only short-term effects, so in general, it can only be said that it may be useful.

DC-CIK Biological Immunity** is to collect human autoimmune cells, after in vitro culture, so that their number increases thousandfold, the targeted killing function is enhanced, and then infused back into the human body to kill pathogens, cancer cells, and mutant cells in blood and tissues, break immune tolerance, activate and enhance the body's immunity. Therefore, DC-CIK biological immunity** can quickly recover the immune damage to the body caused by surgery and improve the body's immunity.

In recent years, with the efforts of biologists and oncology medical experts, DC-CIK biological immunity has entered people's anti-cancer vision, complementing each other with the three traditional methods, and is playing a firm anti-cancer role, creating a new path for saving the lives of cancer patients.

Grade 3 Hospital] -- Beijing 304 Hospital Tumor Biology Center [Oncology Specialist] -- Gong Yu, Hou Peng.

Authoritative**] --dc-cik biological immunity**.

To ask this question, we must first know what is DC cell biological immunity**??

DC cells (dendritic cells) are a special type of white blood cell with membranous dendritic protrusions (the surface of the cell appears to have many antennae). As a very important component of the body's immune system, it is a powerful specialized antigen-presenting cell (specialized in recognizing harmful substances in the body) that activates T cells to initiate an immune response. (It is equivalent to labeling antigens such as cells and foreign bodies that are harmful to the human body as "bad guys" and telling other immune cells to kill them).

DC cell biological immunity**: It is to extract nuclear cells from the patient's blood, induce them to differentiate into DC cells through cytokines in vitro, and then use special treatment to make mature DC cells with special antigens (such as containing hepatitis B virus information, or tumor identification information, etc.), and infuse these mature DC cells back into the patient, so as to activate the patient's own immune system to achieve the effect of cure.

Now DC cell biological immunity** is mainly used in:

**Hepatitis B, cirrhosis and other liver diseases: the effect is still good;

**Cancer: There is a certain effect, but you know, if you want to be thorough**, still.

Risks: Since the human immune system is a very delicate and complex system, whether some of the substances added in the above cell induction culture process in vitro will affect the human immune system, whether it will overstimulate the immune system, etc.

According to experts from Chongqing Cancer Hospital, the preoperative application of early tumors can comprehensively improve the immune function of patients, especially avoid the decline of immune function caused by surgical stress, and improve the success rate of surgery. After the completion of surgery, radiotherapy or chemotherapy, it can restore and strengthen its immune anti-tumor effect, eliminate residual cancer cells in the body, reduce the ** and metastasis of tumors, and improve the ** rate.

The application between and after the course of radiotherapy and chemotherapy can enhance the efficacy of radiotherapy and chemotherapy, improve the tolerance of chemotherapy and radiotherapy, and reduce their efficacy.

What are the tumors that can be immunologically applied by DC-CIK: At present, the international application of DC-CIK biological immunity technology has been very mature. The clinical research of the Tumor Biology Center of Chongqing Cancer Hospital has shown that it plays an important role in clinical application, especially for tumor patients after surgery, to remove residual microscopic metastatic lesions, prevent the spread of cancer cells, and improve the patient's own immunity, and has high killing activity for colon cancer, breast cancer, gastric cancer, colorectal cancer, ovarian cancer, etc.

The use of DC-CIK biological immunity** can effectively target lung cancer, liver cancer, gastric cancer, breast cancer, pancreatic cancer, malignant melanoma cancer, kidney cancer, prostate cancer, ovarian cancer, colon cancer, rectal cancer, oral cancer, laryngeal cancer, nasopharyngeal cancer, tongue cancer, lip cancer, etc.