What does enrofloxacin do, what does enrofloxacin do

Enrofloxacin is used for the prevention and control of 6 diseases:

1. Bacterial respiratory diseases: infectious pleuropneumonia, Haemophilus parasuis, porcine lung disease, streptococcus, paraporcine and other diseases;

2. Digestive tract diseases: Escherichia coliform disease (piglet yellow dysentery, edema), salmonellosis, treponema dysentery, leptospira.

3. Genitourinary system: urethritis, cystitis; sow mastitis-metritis-alactic syndrome;

4. ** disease: exudative dermatitis, necrobacillus, etc.;

5. Bacterial infections secondary to viral diseases: such as parapigs, streptococcal disease, epierythrocytosis, etc.;

6. Various mycoplasmosis: swine asthma, porcine synovial fluid mycoplasma infection, and rhinoplasma infection.

2. Clinical use of enrofloxacin:

1. Respiratory diseases and intestinal diseases of pigs.

Piglets often have coughing and diarrhea after weaning, most of which are caused by diseases such as parapigs and infectious pleuropneumonia, and enrofloxacin has a strong killing effect on these pathogens.

Specific plan: 10% enrofloxacin is added to each ton of feed after weaning, and it is used for 7 days.

2. Joint enlargement or sepsis caused by streptococcus and parapigs.

Enrofloxacin injection, amoxicillin + analgesia were injected intramuscularly once a day for 3 days.

3. Used for pig asthma**.

Add 1 kg of 10% enrofloxacin and 1 kg of 10% doxycycline hydrochloride per ton of feed** for 7-10 days, and it has a good effect.

4. Prevent infectious pleuropneumonia and swine lung disease in fattening pigs.

1 kg of 10% enrofloxacin and 1 kg of 10% florfenicol were added to each ton of feed for 7 days.

5. Prevention and treatment of metritis in sows.

1 kg each of 10% enrofloxacin and 10% lincomycin per ton of feed; Enrofloxacin is given intramuscularly in milligrams per kilogram of body weight.

6. Porcine exudative dermatitis**.

Use potassium permanganate water (warm water) or 3% hydrogen peroxide to wash the scab and exudate of sick pigs, and apply a mixture of waste engine oil and penicillin after cleaning, once a day, 2-3 times. Intramuscular injection of 10% enrofloxacin injection + ceftiofur for injection, 1 time a day, 2-3 times.

It seems to be a veterinary drug.

Indications] It is suitable for infection or mixed infection caused by various sensitive bacteria.

1. Yellow dysentery (within 7 days old) and white dysentery (within one month old) in piglets caused by Escherichia coli;

2. Hemorrhagic enteritis, diarrhea, food poisoning, typhoid fever, paratyphoid fever, and secondary infections of infectious gastroenteritis and epidemic diarrhea caused by sensitive bacteria;

3. Calf diarrhea, lamb dysentery, pasteurellosis caused by sensitive bacteria;

4. Edema caused by swine streptococcal disease and Escherichia coli;

5. Porcine asthma, atrophic rhinitis, pneumonia, bronchopneumonia;

6. Chicken dysentery, Escherichia coliformosis, avian cholera, chronic respiratory diseases.

1. Enrofloxacin can be used as an animal drug, with a long half-life in the animal, good tissue distribution, a broad-acting bacteriostatic agent, and has antibacterial effect on gram-positive bacteria, negative bacteria and mycoplasma, and has been used in the control of vibriosis and coliform disease in farmed fish.

2. This product is a synthetic third-generation quinolone antibacterial drug, also known as ethylciprofloxacin, which was approved by the FDA on October 4, 1996, and is a quinolone antibacterial drug for livestock, poultry and aquatic products. It can bind to bacterial DNA gyrase subunit A, thereby inhibiting the cleavage and ligation function of the enzyme, preventing the replication of bacterial DNA, and showing antibacterial effect.

Ofloxacin is a fungicide that inhibits the synthesis and replication of DNA and causes bacterial death through the A subunit of the bacterial DNA helix residual enzyme used by the author. Enrofloxacin, also known as enrofloxacin, is a chemically synthesized bacteriostatic agent of fluoroquinolones, which is a yellowish or light yellow crystalline powder, bitter in taste, insoluble in water, soluble in sodium hydroxide solution, methanol and liquid cyanomethane and other organic solvents.

Enrofloxacin is a coarse broad-spectrum antibiotic that has a good inhibitory effect on a variety of bacilli and cocci. In aquaculture, enrofloxacin nucleus can be used to prevent and improve a variety of diseases, such as bacterial diseases, fish diseases, etc. Enrofloxacin can be given to fish and shrimp by feed, water addition, etc.

Experiments have proved that enrofloxacin can effectively prevent and improve common diseases in aquaculture, improve seedling rate and breeding efficiency.

However, excessive use of enrofloxacin can cause harm. Enrofloxacin accumulates in the human body for a long time, which may lead to damage to the body's immune system and cause various diseases. Therefore, when using enrofloxacin, it is necessary to strictly control the dosage and duration of use to avoid potential harm to the aquaculture environment and human health.

In conclusion, enrofloxacin plays an important role in aquaculture. However, we must use enrofloxacin correctly and avoid abuse and misuse. Only in this way can the maximum benefits of enrofloxacin be maximized, while protecting the health and sustainability of the aquaculture industry.

1. Gastrointestinal reactions are more common, which can be manifested as abdominal discomfort or pain, diarrhea, nausea or vomiting.

2. Central nervous system reactions may include dizziness, headache, drowsiness or insomnia.

3. Allergic reactions, rashes, itching, occasional exudative erythema multiplea and angioedema. A small number of patients have photosensitivity.

4. Crystallusuria can occur when this product is applied in large doses or when the urine pH value is above 7. In order to avoid the occurrence of crystalluria, it is advisable to drink more water and maintain a 24-hour urine output of more than 1200ml.

5. Seizures, mental abnormalities, irritability, impaired consciousness, hallucinations, tremors.

6. A small number of patients can have elevated serum aminotransferase, increased blood urea nitrogen and decreased leukocytes in the surrounding blood images, which are mostly mild and transient.