What is the role of interferon? What is Interferon?

Interferon is the nemesis of the virus and is recognized as one of the most powerful new drugs since the birth of antibiotics. It is effective against viral diseases such as cancer, influenza, and hepatitis, all of which are intractable diseases for which there is no decisive means. For example, when cancer cells form in cancer patients, they multiply at an alarming rate.

But when patients are injected with interferon, the rate of proliferation of cancer cells slows down considerably, and sometimes even makes cancer cells disappear. It has been proven that interferon has the best effect on osteosarcoma, multiple myelopathy, melanoma, ** disease and lymphoma.

In short, any disease caused by a virus, it can be prevented and**.

This drug is indicated for viral diseases and certain malignancies. It is mainly used in chronic hepatitis B, chronic hepatitis C and hairy cell leukemia. It is effective against viral diseases such as genital warts, chronic cervicitis, herpetic keratitis, herpes zoster, epidemic hemorrhagic fever and pediatric respiratory syncytial virus pneumonia.

It also has good efficacy against other viral diseases and malignant tumors such as chronic myeloid leukemia, melanoma, lymphoma, etc. Interferon must be used under the guidance of an experienced doctor.

Nowadays, antibiotics have become an important drug that is widely used in medical treatment, and all kinds of dangerous bacterial infectious diseases have been effectively controlled by antibiotics. However, judging from the current trend, the future drug rookie may be the world of interferon.

Interferon, as the name suggests, is a substance that acts as an interference. In 1957, two British scientists, Isaacs and Lindenman, first discovered that when a virus infects the human body, the white blood cells of the patient's blood produce and release a substance. This substance has a very wonderful effect, it can interfere with and inhibit viruses and other microorganisms to "do evil", so scientists call this substance "interferon".

Interferon has been shown to be particularly effective against diseases caused by colds, chickenpox, hepatitis, measles, keratitis, shingles and wart viruses. Recent studies have reported that interferon also has an inhibitory effect on liver cancer cells, and the effect is much better when applied to patients with early-stage cancer than in advanced stages. However, interferon is extremely difficult to come by, and only grams of interferon can be extracted from 45,000 liters of human blood.

It is exciting that a professor of molecular biology at the University of Zurich in Switzerland and some scientific and technological personnel have successfully produced interferon by transplanting the interferon-producing gene into Escherichia coli according to the structural principle of genetic genes, creating a new and simple way for artificial cultivation to produce interferon. In the near future, the budding "interferon" will become a very ideal drug like the current antibiotics, and establish merit for the cause of human health.

Interferon is a small molecule glycoprotein that has antiviral, antitumor, and immune-enhancing effects!

Interferon is a protein that inhibits the proliferation of viruses within cells. It is produced by human and animal cells under the induction of viruses, bacteria, fungi, protozoa, rickettsia, etc. Any kind of induced interferon can inhibit the proliferation of a variety of viruses, but it has a certain selectivity for the object it acts on, that is, the animal cells that produce interferon only have an inhibitory effect on the cells of animals of the same species or the same genus.

Instead of directly inhibiting viral proliferation, interferon induces cells to synthesize another class of proteins that inhibit viral proliferation. Recently, scientists have discovered that plants are also capable of producing interferon. The role of interferon in the fight against viruses, including certain cancers, is still being explored.

Interferons are a group of cytokines produced by immune cells that can transmit information between cells, and are proteins or small molecule polypeptides with immunomodulatory and effector functions. It can interfere with the replication of viruses, so as to have antiviral effects. I won't say much about the specific mechanism, hehe!

Over the years, scientists have used molecular cloning technology to artificially express drugs with natural interferon activity, which we often call interferon, using animal or human cells or yeast. There are three types of natural interferons: alpha, gamma, and beta, and there are also three types of artificially expressed ones. It is applied to the clinic for viral diseases according to different needs.

Interferon is a class of glycoproteins, which has a high degree of species specificity, so animal interferon is ineffective for humans, and interferon has antiviral, inhibition of cell proliferation, regulation of immunity and anti-tumor effects.

Interferon has been used for 15 years as an antiviral**. Professor Xu told reporters that according to years of clinical observation, after using interferon for half a year to one year, the HBEAG conversion rate is 30%-40%, and the antiviral effect of the long-acting interferon pyroxin that was marketed in China last year is better. It has the advantage of having both antiviral and immunomodulatory effects, and the immunomodulatory effects can be continued.

If HBEAG turns negative, the efficacy remains stable; Thirdly, for patients who use interferon, a new interferon or nucleoside drug can still achieve better efficacy. It is known that interferon is more effective in women, patients with short course of disease, non-mother-to-child transmission, mild liver fibrosis, and no other hepatitis virus infections.

Comparison of the advantages and disadvantages of nucleosides and interferons:

1. The course of interferon treatment is shorter and larger.

The advantage of interferon is that the course of treatment is relatively short, about one year, and the general course of treatment is one year to control the virus. But the disadvantages of interferon are also obvious. After hepatitis B patients are given interferon, *** is larger than nucleoside drugs.

There are many common *** after interferon, such as some fever, some white blood cell inhibition, and so on. There are also side effects of interferon, including loss of appetite, general fatigue, and so on. However, most patients can tolerate these side effects.

In addition, there is a lack of perfection in interferon, that is, the response rate of interferon is limited. There are about 30%-40% of people who can really get a good response rate, and 60%-70% of people have a bad response effect. Here are the advantages and disadvantages of interferon.

2. The response effect of nucleoside drugs is good, but the course of treatment is long.

Then nucleosides are just the opposite of interferons. The advantage of nucleosides is that they respond very well. More than 90% of people can respond well, and there is no ***.

One pill a day, very safe. The disadvantage of nucleosides is that they take a long time.