-
ER estrogen receptors, PR progesterone receptors: usually this type of laboratory is the most common and important. They determine whether the tumor is hormone-sensitive, and also play an important role in prognostic assessment.
There are ER and PR in normal breast epithelial cells. When cells become cancerous, ER and PR are partially and completely missing. If the cells still retain ER and/or PR, the growth and proliferation of this breast cancer cell is still regulated by endocrine and is called hormone-dependent breast cancer; If ER and/or PR are missing, the growth and proliferation of this breast cancer cell is no longer regulated by endocrine and is called hormone-independent breast cancer.
Immunohistochemistry assay C-ERBB2 oncogene: low expression in normal breast tissue, can increase in breast cancer tissue, its expression is positively correlated with breast cancer grade, lymph node metastasis and clinical stage, the higher the expression rate, the worse the prognosis may be. C-ERBB2 usually requires FISH to confirm whether HER2 is a true positive.
KI-67: typically associated with the rate of tumor growth; Associated with prognosis in patients with negative breast cancer, particularly lymph node metastases, to determine the use of adjunctive chemistry**. p53 gene:
Breast cancer cells with high p53 mutation rate have strong proliferative activity, poor differentiation, high malignancy, aggressiveness and high lymph node metastasis rate.
-
T represents tumor size, and 2 represents tumor larger than 2cm and less than 5cm.
n represents regional lymph nodes and 2 represents regional lymph nodes with adhesions.
m represents distant metastasis, and 0 means no distant metastasis. Chemotherapy and radiation therapy should be given.
-
Summary. Hello, breast cancer T2 refers to a lump larger than 2 and less than 5 cm, and N3A refers to the number of lymph nodes metastasized to more than 10, so the stage is stage IIIC, that is, advanced breast cancer.
What does right breast cancer pt3n2m zero iiia mean (number below the letter) Dear, hello, I am inquiring for you here, please wait a while, I will reply to you right away.
Hello, breast cancer T2 refers to the mass with traces greater than 2 and less than 5 cm, and N3A refers to the number of lymph nodes metastasized to more than 10, so the stage is stage IIIC, that is, Sun Lu's advanced breast cancer.
-
P: refers to the pathological stage, which should generally be the stage after surgery based on histopathological results.
tx: primary tumor cannot be assessed.
N2: 4-9 axillary and fossa lymph node metastases; or in the absence of axillary lymph node metastases, ipsilateral internal mammary lymph node transfer is detected by imaging.
m0: No distant metastases were seen.
Answer** is the 2020 sixth edition of the NCCN Clinical Bed Practice Guidelines for Breast Cancer.
-
Analysis: Hello, look at what you said about the condition this time, it depends on the condition of breast cancer, and the pathological biopsy after surgery shows that there is lymphatic metastasis, which means that your condition is in the middle and advanced stages.
Guidance: Chemotherapy is routinely performed after surgery, but because chemotherapy is large and has great harm to the body, it should be combined with the diagnosis of traditional Chinese medicine during chemotherapy to consolidate, which will also have a very good effect.
Continue to take fluon orally. CerBB2 (++ Herceptin is not necessarily used, a FISH test can be done, and it is meaningful for positive patients. However, if you have no financial ability, you don't need to consider it.
If you don't know the status of lymph node metastasis, you can see if you need local radiotherapy. >>>More
Bolinco for biotechnology - answer for you: the cells raised are all breast cancer cells, the following types: 1. MCF-7 is a very good human breast cancer cell, the medium can be used DMEM or RPMI1640, 10 15 calf serum can grow very well. >>>More
However, due to cancer metastasis in the axillary lymph nodes, it is necessary to receive chemotherapy 2 to 3 weeks after surgery, and the chemotherapy regimen is fluorouracil. If the patient's physical condition can not tolerate the conventional chemotherapy in the hospital, the use of oral chemotherapy drugs - Heroda can be considered, which is low and safe. However, the patient is 41 years old and can still tolerate the conventional chemotherapy in the hospital according to normal. >>>More
Of course, soy milk, especially soy milk, will be able to regulate hormones in the body, and breast cancer is caused by hormone level disorders in the body. My mom is, now it's okay, I bought a soymilk maker at home, and I often do it. The rest will not affect the body, as long as it does not contain melamine!