Is goiter due to iodine deficiency?

Hello, according to your description, you said that iodine deficiency can cause goiter, mainly due to the fact that iodine is an important raw material for the synthesis of thyroid hormones, and long-term iodine deficiency in the diet reduces thyroid hormone synthesis. The level of thyroid hormone in the blood decreases, and the negative feedback effect on the adenohypophysis is weakened, resulting in an increase in the secretion of thyroid-stimulating hormone in the adenohypophysis. Thyroid-stimulating hormone promotes thyroid cell proliferation, which can lead to thyroid enlargement.

If it is due to an iodine deficiency of the thyroid gland. Iodine supplementation is required in a timely manner**. Symptoms of goiter can be relieved by iodine supplementation.

Is it generally due to iodine deficiency?

First, the relative lack of iodine. When the environment is deficient in iodine and the concentration of inorganic iodine in the blood decreases, the thyroid tissue proliferates, and its iodine uptake function is enhanced, and the thyroid gland tries to take enough iodine from the blood in a state of low iodine to ensure the synthesis of sufficient thyroid hormones to supply the physiological needs of the body's tissues.

Second, due to long-term intake of too much iodine, there are too many inorganic iodine ions in the thyroid tissue, which hinders the organic process of iodine, resulting in a decrease in thyroxine synthesis, and high iodine may also inhibit the release of thyroxine, making the blood thyroxine more deficient, thus increasing the secretion of thyroid-stimulating hormone and causing goiter.

Answer] :d iodine deficiency leads to excessive secretion of thyroid-stimulating hormone in the body, resulting in diffuse enlargement of the thyroid gland, which is pathological hyperplasia.

Endemic goiter, caused by iodine deficiency, is a very old disease, commonly known as "big neck disease", which is quite familiar. But most people don't know that high iodine in the diet can also cause goiter, which is called high-iodine goiter. In the teaching of physiology and hygiene, we found that some teachers often indiscriminately emphasize the need to eat more iodine-rich foods such as kelp when talking about the prevention and treatment of goiter, but in fact, this view is very incomplete.

There are two main types of goiter: endemic goiter and hyperiodine goiter. Although the symptoms of the patients are goiter, the cause of the disease is the opposite. As for the causes of endemic goiter and its prevention and treatment, the current physiological and health textbooks have been introduced in more detail, and will not be repeated here.

This article only briefly introduces iodine goiter and its prevention.

Hyperiodine goiter, especially endemic hyperiodine goiter, is a newly discovered disease in the past decade. The disease was first identified as endemic to the coastal areas of Hokkaido, Japan. In recent years, similar reports have been reported in low-lying saline-alkali areas along the coast and inland of China, and some disease areas (such as Hebei and Shandong) are located in oilfield areas.

Investigations have shown that excess iodine is the main cause of this goiter epidemic. Regarding the pathogenesis, it is currently believed that in a high-iodine environment, in order to store as much iodine as possible, the body stores iodine synthetic colloids (inorganic iodine cannot be stored in the body) in the thyroid follicular cavity.

When this glial build-up occurs, the thyroid gland becomes significantly enlarged, known as a hyperiodine goiter. The incidence of the disease is higher in women than in men, and the peak incidence is between the ages of 11 and 25. Taking too much iodine-containing drugs can also cause a hyperiodine goiter.

After goiter, iodine-containing diet is usually stopped for a few weeks to several months, and the lump can be significantly reduced or healed. In terms of prevention, it is necessary to first identify vectors that carry high levels of iodine and take appropriate measures to remove iodine according to local conditions.

High-iodine goiter and endemic goiter, both of which are bilateral diffuse thyroid enlargement, the patient himself has no self-conscious symptoms, and the prominent feature is only "thick neck", which is difficult to distinguish by appearance. In addition to this, other thyroid diseases such as hyperthyroidism also have goiter. Therefore, patients with goiter should not be blindly iodized, but should seek medical attention as soon as possible. Otherwise, there is a risk of the opposite result.

The main common thyroid diseases are hyperthyroidism, hypothyroidism, hypothyroidism, thyroid tumors, thyroiditis, thyroid cysts, and complications of hyperthyroidism.

The enlarged thyroid gland caused by the defect is also known as the Great Neck Disease. Iodine deficiency mainly leads to insufficient thyroxine synthesis, resulting in compensatory thyroid hyperplasia (compensatory hyperplasia is to synthesize thyroxine more). So the thyroid tissue will become larger, that is, the thyroid gland will be enlarged.

Both statements are true, but from different angles. Iodine deficiency leads to low thyroid hormone secretion, which increases thyroid-stimulating hormone secretion, which increases thyroid absorption of more iodine. This causes endemic goiter. Take care to distinguish between thyroid hormone and thyroid-stimulating hormone.

Iodine deficiency leads to decreased thyroid hormone synthesis and therefore increased thyrotropin-releasing hormone and thyroid-stimulating hormone secretion, resulting in endemic goiter.

Iodine is an important raw material for thyroxine synthesis, when the iodine content in the diet is insufficient, it will lead to insufficient thyroxine synthesis, and promote the secretion of TSH by the pituitary gland through a negative feedback regulatory mechanism, acting on the thyroid gland to proliferate thyroid cells, so goiter is produced.

Suggestions: Goiter is mainly manifested as symptoms and signs such as palpitations, chest tightness, heat intolerance, excessive sweating, hand tremors, insomnia, hyperphagia, weight loss, fatigue, diarrhea, goiter and proptosis. The onset is acute, with enlargement and hardness on one or both sides of the thyroid gland, accompanied by local pain, and often radiating behind the ears and at the top of the back of the head, and the whole body may have chills and fever.