Is there a doctor who is an expert in treating the blood disorder MDS?

Pharmacokinetics of hirudin The anticoagulant and antithrombotic effect of leeches depends on its concentration in the blood. Take the pharmacological effect of antithrombotic effects as an example: the effective dose and blood concentration of antithrombotic are different for different test models.

For example, the blood concentration required for venous thrombosis in rats is one-twentieth of heparin, while DIC (disseminated intravascular coagulation) is only one-fiftieth of heparin. Because during venous thrombosis, the main plasma coagulation factors are activated, leading to the formation of thrombin, and hirudin is the strongest thrombin inhibitor. Arterial thrombosis, on the other hand, requires higher concentrations.

Its concentration ratio is 5 times that of ** venous thrombosis, and animal experiments have found that rats are instilled with hirudin by intravenous infusion, and the plasma concentration can completely inhibit the formation of venous thrombosis. To completely inhibit the formation of arterial thrombosis, it is necessary to administer 200AT-U kg for 60 minutes.

Taking time (three to five days), the effect is as follows: the lumps and thrombis in the blood are gradually dissolved, the blood flow begins to be smooth, the symptoms of dizziness and headache gradually disappear, and there are a few opposite conditions, which are normal reactions and will disappear after a period of time.

2. Taking time (five to ten days), effect performance: sleep quality improvement, energy improvement, may also be the opposite: poor sleep, dizziness, fatigue, are normal reflections, and will disappear after a period of time.

3. Taking time (10 days to half a month), the effect is as follows: increased appetite, enhanced blood supply and oxygen supply to tissues and organs, full of energy and smooth breathing.

4. Taking time (half a month to one month), the effect is as follows: the frequency of bowel movements increases, the toxins in the blood are excreted with the feces, and the sour odor.

5. Taking time (one to two months), effect performance: blood viscosity decreases accordingly, blood flow is relatively smooth, feeling relaxed and energetic.

6. Taking time (two to three months), the effect is as follows: the blood viscosity index gradually returns to normal, the original symptoms of being prone to sleepiness, dozing off and poor spirit disappear, walking vigorously, heartbeat is strong, and pigmented spots and age spots gradually subside.

7. Taking time (long-term use), effect performance: smooth blood flow, feeling relaxed, energetic, effectively preventing the occurrence of cardiovascular and cerebrovascular diseases, patients who have had stroke can fundamentally improve the symptoms of stroke and sequelae and the occurrence of secondary stroke.

Because of the use of serum queen, the blood viscosity decreases, the blood circulation improves, the blood flow accelerates, and the functions of various parts of the body change accordingly, which shows that the serum queen has produced an effect in the body, which is a good phenomenon.

Have you done bone marrow aspiration, bone marrow biopsy, chromosome, karyotype analysis and differential diagnosis, MDS is divided into many types, FAB divides MDS into RA, RAS, CMML, RAEB, RAEB-T There are several more types in the world, this disease belongs to clonal hematopoietic stem cell disease, and it has also become the pre-leukemia, that is, there is the possibility of transformation to leukemia, and we must actively carry out symptomatic treatment to achieve long-term survival after clinical remission, You can go to the Chinese Blood Disease Network to learn more about this disease.

Does MDS refer to myelodysplastic syndrome, I know that there is a medicine called lenalidomide (leilidomide), and the effect is said to be very good. It is possible to help you if you need **, I have friends in India.

Dr. Liu Qingchi. Please search the Internet for "hematopoietic mystery".

Shanghai Yueyang Hospital has a high level of traditional Chinese and Western medicine, or go to the Hematology Department of Xiyuan Hospital, China Academy of Chinese Medical Sciences.

Hello, I'm glad to answer for you: Of course you can**, but the **rate is relatively low. MDS is a disease of myelodysplasia, most patients are unable to **, and only a few patients can be transplanted with hematopoietic stem cells**.

The English abbreviation of myelodysplastic syndrome is MDS, which belongs to the malignant clonal disease of hematopoietic stem cells, also known as pre-leukemia, which is common in the elderly over 50 years old, and is clinically characterized by pathological hematopoiesis and high probability of transformation into leukemia. With current medical technology, MDS is still difficult, and only a few patients can be transplanted after allogeneic hematopoietic stem cells. Once the patient is found to have MDS, the patient needs to undergo an allogeneic hematopoietic stem cell transplant as soon as possible, and allogeneic hematopoietic stem cell transplantation is the most likely method for this disease.

If MDS is not available, the patient will have a lot of complications as they age.

Hello MDS is a heterogeneous disease. The effective rate of integrated traditional Chinese and Western medicine in the regulation of blood production is 80%, and the rate is 30%-50%.

The latest pharmacological studies have found that many Chinese medicines can regulate the proliferation and differentiation of hematopoietic cells at the molecular level, such as arsenic acid in traditional Chinese medicine promotes the differentiation and apoptosis of promyelocytes by degrading PML RAR gene products; Leukin can control the proliferation of K562 leukemia cells and induce apoptosis; Fangji can down-regulate the expression of MDR of multidrug resistance genes and reverse cell drug resistance; There are also traditional Chinese medicines that regulate the differentiation and proliferation of blood cells through the influence of hematopoietic stromal cells. According to the traditional theory of traditional Chinese medicine and the latest pharmacological research, combined with modern science and technology, Western medicine disease differentiation, Chinese medicine syndrome differentiation, and the organic combination of Chinese and Western medicine, we have developed birth blood regulation and control of MDS, so that the hematopoietic abnormalities of MDS can be corrected and normal hematopoietic function can be restored.

Myelodysplastic syndrome is considered to be hematopoietic dysfunction caused by abnormal proliferation and differentiation of hematopoietic stem cells, which is mainly manifested as peripheral blood pancytopenia, bone marrow cell proliferation, and morphological abnormalities of mature and naïve cells, that is, pathological hematopoiesis. Some patients can develop acute leukemia; Some can die from infection, bleeding, or other causes. According to the patient's condition, Western medicine mostly uses hormones, differentiation inducers, combined chemotherapy and other diseases, MDS patients are not sensitive to chemotherapy, the efficacy is not good, the remission period is short, this patient has gastrointestinal diseases, chemotherapy may aggravate ulcers.

An increased ratio of monocytes is partly related to a decrease in the number of red blood cells in the blood, and the disease itself can also cause an increase in monocytes.

During the illness, the resistance is poor, so it is necessary to pay attention to health protection, prohibit smoking and alcohol, pay attention to food hygiene, and disinfect the living environment. While preventing infection, we should also pay attention to improving our own disease resistance, and it is recommended to combine Chinese herbal medicine to reduce the toxicity of chemotherapy, improve the quality of life, and prolong life.

Myelodysplastic syndrome (MDS), also known as pre-leukemia, refers to a group of blood diseases caused by damage to bone marrow hematopoietic stem cells caused by certain factors, with bone marrow pathological hematopoiesis, one or more lineages of blood cytopenia in peripheral blood, morphological abnormalities, immune function, and hemostatic dysfunction as the main manifestations. The disease** is unclear and may be related to certain factors such as viral hepatitis, cancer after chemoradiotherapy, exposure to benzene, organophosphates, radiation, and some cytotoxic drugs.

MDS is more common in the elderly over 60 years old, and rare in children, but in recent years, the number of pediatric cases has gradually increased, and the main clinical manifestations of the disease are bone marrow failure, a series of symptoms caused by red blood cells, white blood cells, and thrombocytopenia, such as anemia, infection, bleeding and lymph reticular system infiltration and hyperplasia, such as hepatosplenite, lymphadenopathy.

Due to the different lengths of the natural course of MDS and the complexity of the disease, it brings certain difficulties to the patient, and can only be given according to the specific condition of each patient. It is best to stage by type**, e.g., RA can be by aplastic or general support**; RAS can be added with vitamin B, etc. according to RA**, RAEB and RAEB T do not need to be strong ** in principle, but drugs that induce cell differentiation can be tried, and some RAEB T cases can also be combined with chemotherapy or bone marrow transplantation according to acute leukemia according to the condition. The western medicine of MDS** has the following points:

1) Support**: such as blood transfusion, anti-infection, etc.

2) Vitamins**: such as vitamin B12, etc.;

3) Hormones: corticosteroids and male hormones;

4) Induced differentiation**;

5) aggressive chemotherapy;

6) Bone marrow transplant.

** and the prognosis depends on the specific pathological type of the patient and ** condition. The patient's immunity is very low, so it is necessary to prevent infection and pay attention to hygiene.

Myelodysplastic syndrome is currently considered to be hematopoietic dysfunction caused by abnormal proliferation and differentiation of hematopoietic stem cells, and is a very dangerous disease. Some patients develop acute leukemia after a certain period of MDS; Some die from infection, hemorrhage, or other causes and never transform into acute leukemia during the course of the disease.

The condition of bone marrow dysfunction syndrome should be determined according to the patient's condition and situation, and each patient's condition is different and should be determined according to the actual situation. Pathological hematopoiesis is the basic feature of MDS, and therefore a diagnostic condition for MDS, but pathological hematopoiesis, as the main indicator for diagnosing MDS, has its weaknesses in terms of repeatability, specificity and sensitivity, especially in some atypical cases. Therefore, the peripheral blood and bone marrow must be carefully observed for pathological hematopoiesis to confirm the diagnosis of MDS.

Shijiazhuang Huikang Traditional Chinese Medicine Hospital is a good way to balance immunity **** bone marrow abnormality syndrome.

The Institute of Hematology, Peking University People's Hospital, ranked first in Asia. The Institute of Hematology of Beijing People's Hospital is a comprehensive hematology research institute integrating medical treatment, teaching and scientific research, which was established in 1981 by Professor Lu Daopei, a famous hematology expert in China. Now it is a key discipline of the Ministry of Education, a national talent training base, and a national drug clinical research base, and has successively undertaken a number of national, provincial and ministerial projects such as the national "863" high-tech research plan, the national "Ninth Five-Year Plan" research plan, the national natural science ** project, and the key project of clinical disciplines of the Ministry of Health.

At present, the main research direction is the malignant diseases of the blood system.

The Institute of Hematology of Beijing People's Hospital has 4 wards and 110 beds, with many laboratories such as cell dynamics, cell biology, cytogenetics, cell morphology and pathology, coagulation, molecular biology and hematopoietic stem cell transplantation, with 22 professors and associate professors, 3 doctoral supervisors, 10 master's supervisors, and more than 20 doctoral degree students.

Peking University First Hospital, Beijing ****, 301 Hospital can be.

The way of this disease is much better than that of a good 3A hospital in Beijing, and the key is that as long as the initial diagnosis is accurate, the first aspect should be basically the same.

The choice of hospital depends on the specific condition of the patient.

Myelodysplastic syndromes are a heterogeneous group of acquired clonal disorders, the basic lesions of which are clonal hematopoietic stem and abnormal development of progenitor cells, resulting in ineffective hematopoiesis and an increased risk of malignant transformation. Manifested by an increased or normal number of hematopoietic cells of all lines in the bone marrow, but morphological changes with obvious dysplasia; There is a marked decrease in blood cells of all lineages in the peripheral blood. There is also a high risk of developing acute myeloid leukemia.

If you want to treat this disease from the root, you need to combine Chinese herbal medicine to treat it from the root. A good plan is very important, and the wrong medication will also aggravate the condition. Dr. Zhang.

Hello! If the diagnosis is confirmed, hematopoietic stem cell transplantation should be performed as soon as possible, and bone marrow transplantation or umbilical cord blood transplantation can be used as soon as possible, and the efficacy is certain.

Dr. Xu Shixia solemnly reminds: skin deficiency can not fully understand the condition of patients due to non-combustible posture burning, the above suggestions are for reference only, please go to the hospital for specific diagnosis and treatment under the guidance of doctors! ）

Xu Shixia of the Naval General Hospital.