What does this pathological diagnosis of breast cancer mean and how does it need to be treated?

The stage of T1N0M0 is still a relatively early tumor. Although immunohistochemistry is not ideal, it is still relatively good overall. The prognosis should not be poor.

Chemotherapy should be done actively according to the doctor's instructions.

Radiation therapy can be left out.

Estrogen and progesterone receptors are negative, so endocrine cannot be used**.

Hersetin** is relatively expensive, requiring more than 20,000 per shot. If the economy is very good, you can try it. If it is general, it is not necessary for the time being.

This situation is a bit serious Be careful not to get angry Anger will aggravate the condition Chemotherapy is not chemotherapy Incomplete information is provided Sure it is not three negatives.

Invasive ductal carcinoma should be considered clinical stage 2 It can also be regarded as the middle stage of breast cancer and there has been obvious axillary metastasis But your mother's primary lesion is not large It is recommended to go for breast cancer modification ** or breast conservation ** surgery Combined with chemotherapy after surgery It should be said that the five-year survival rate is still quite high But if you don't do surgery, it's just chemoradiotherapy** It should be said that it is not ideal This is not a disease that can be delayed If you hesitate for a while, I am afraid that you will lose the opportunity for surgery At that time, you will really have to count down So I suggest that I go to a larger general hospital as soon as possible Listen to the doctor's opinion Surgery actively** I am a breast doctor Although I have only been working for half a year, you have to believe that the advice given to you is correct Hurry up and don't delay I wish you a good day**.

It is more serious, and the pathology is not very good, is lymphatic metastasized? Of course, chemotherapy should be done, and endocrine ** can not be used in the follow-up, and HER2 is not a strong yang targeted drug** may be ineffective, so it is actually three yin, and it is recommended to do a fish to see if HER2 is strong yang, if strong yang use Hersedin or lapatinib.

Hello, I'm a breast surgeon.

1,3 cm large invasive ductal carcinoma grade 2 with 2 28 metastases in axillary lymph nodes, postoperative synthesis is required for active synthesis**.

2. Immunohistochemistry of puncture pathology Er 3+, C-2 -, Ki67 60%, postoperative immunohistochemistry Er 3+, C-2 2+, Ki67 80%, although there may be human subjective error, there will be a certain drift in immunohistochemistry before and after neoadjuvant. According to the current large-sample statistical analysis, the drift rate of ER, PR is about 20%, and the drift rate of C-2 is about 5%.As far as your mother's condition is concerned, the postoperative comprehensive ** plan should be based on the postoperative ER3+, C-2 2+, and Ki67 80%.

3, C-2 2+, you need to do a FISH examination to determine the amplification of the HER-2 gene, if it is amplified, in order to avoid ** and metastasis as much as possible, in principle, you need to target ** with Herceptin, but the drug is very expensive (even if there is a buy 6 get 8 free activity of the Chinese Cancer Association, it probably takes about 150,000).But even if you can't afford it, testing for HER-2 status is necessary, and chemotherapy can be used to at least give it a little more weight when amplifying.

4, ki67 is an indicator that responds to the proliferation coefficient of tumor cell nuclei, simply put, the higher it is, the faster the tumor grows, your mother's situation is that it is increased, which is not directly related to the effect of chemotherapy itself, but it can guide us to follow-up**, **The intensity may be increased.

5. You said that your mother had some heart problems after chemotherapy, how serious is this problem? What is the current ejection fraction? If the heart is heavier and the tumor shrinks not very significantly during the second treatment, you can consider discussing with your doctor to change the chemotherapy regimen and change it to a purple-shirt-based regimen, which reduces the burden on the heart compared to anthracyclines, and also targets the situation that lymph nodes have metastasis and KI67 hyperproliferation.

6, 2 times of immunohistochemistry are 3+, endocrine ** should be very sensitive and effective for your mother's breast cancer type, and oral endocrine ** drugs are required for 5 years after chemotherapy.

If you don't understand anything, you can continue to ask.

KI67 is a measure of cancer cell activity, and the higher it is, the higher the degree of malignancy.

After looking at your immunohistochemistry, I suggest that you do a FISH test, because you have two plus signs for her-2, and two plus signs do not mean that it is positive, and you also need to do a FISH test to determine whether there is dilation.

In the spring of 2009, my sister was diagnosed with breast cancer in pathological examination, and 4 months after surgery, she was diagnosed with extensive metastasis of the tumor, extreme emaciation, weakness of limbs, and loss of appetite. There are lumps of varying sizes on both armpits and neck. When taking 30 pairs of medicine, various lumps began to become smaller, and when taking 200 pairs of medicine, the swelling disappeared completely, and it has not been ** for more than two years now.

The prescription is as follows, I hope it will be helpful to other breast cancer patients.

Bupleurum 15 grams, Astragalus membranaceus 15 grams, Suzi 30 grams, Codonopsis 30 grams, Prunella vulgaris 30 grams, oysters 30 grams, melon 30 grams, gypsum 30 grams, tangerine peel 30 grams, white peony 30 grams, Wang Buliuxing 90 grams, Sichuan pepper 5 grams, licorice 10 grams, jujube 10 pieces, decoction one dose a day, divided into morning and evening twice, each time to take 3 grams of toad skin powder, 3 grams of beef root powder, 3 grams of Panax notoginseng powder.

It is recommended to combine traditional Chinese medicine for internal and external application**, for more information, QQ consultation.

The patient's current condition is that the cancer cells have not metastasized significantly.

Zhi, lymph nodes have no obvious dao metastasis, which belongs to the early return stage of breast cancer, and should undergo surgery as soon as possible, and the surgery should strive to completely remove the cancer cells, and then if the doctor recommends consolidation through chemotherapy, you still need to follow the doctor's instructions. During the patient's ** period or in the patient's postoperative period, in order to improve the efficacy and reduce the ** rate, the patient can take Shenbaiyi, which contains the traditional Chinese medicine ingredient RG3 has an inhibitory effect on tumor cells, and its own nutritional value is high, and the patient can use it after surgery and during radiotherapy and chemotherapy, which can improve the patient's immunity.

It is not very serious because lymphatic metastases, which are the most common route of metastasis in breast cancer, have not yet occurred.

Early, but immunohistochemistry is not too good, requiring chemotherapy and ongoing endocrine therapy**.

It's clear, you've got breast cancer. Axillary LN (1 17) indicates that 17 lymph nodes in the axillary were taken, and 1 of them had metastases. ihc：

er（+，95%）、pr（+，5%）、her－2（3+）、ki－67（+，60%）。These are the results of immunohistochemistry and are useful in guiding the use of ** drugs.

According to the above postoperative pathological results, breast cancer stage 2, that is, intermediate and early stage;

If the ER is strongly positive, it is recommended to combine endocrine ** after surgery and long-term prevention**;

HER2 is strongly positive and accompanied by lymph node cancer metastasis, if economic conditions allow, Herceptin should be combined (targeted**);

If KI-67 is moderately positive, systemic chemotherapy (CAF regimen, 6 times) must be taken after surgery, and local radiotherapy is required after chemotherapy completion;

The patient's condition is good, actively cooperates**, and the 10-year survival rate is very high.

Combination after surgery is ideal for anti-cancer