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ER, PR, and CerBB2 represent estrogen receptors, progesterone receptors, and epithelial growth factor receptors, respectively. A positive ER or PR positive is preferable because it is effective against endocrine **, while a positive CERBB2 positive is poor because it indicates that the cancer cells are aggressive. Therefore, the above pathological results are not ideal.
For breast cancer, Beijing University Hospital mostly uses Enhuan plus cetaxel chemotherapy. As shown in the table Rubicin Gatesotti. Your mother's lymph nodes have metastases that are eligible for this chemotherapy indication.
Since the white blood cells are low after chemotherapy, care is taken to prevent infection. Eat high-protein foods.
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1. ER, PR: ER, PR are present in normal breast epithelial cells. When cells become cancerous, ER and PR are partially and completely missing.
If the cells still retain ER and/or PR, the growth and proliferation of this breast cancer cell is still regulated by endocrine and is called hormone-dependent breast cancer; If ER and/or PR are missing, the growth and proliferation of this breast cancer cell is no longer regulated by endocrine and is called hormone-independent breast cancer.
C-ERBB2 oncogene: low expression in normal breast tissue, can increase in breast cancer tissue, its expression is positively correlated with breast cancer grade, lymph node metastasis and clinical stage, the higher the expression rate, the worse the prognosis may be. The metastatic tumors were found in all 13 axillary lymph nodes sent for examination, which was not good and the immunohistochemistry was not ideal.
2. The dosage of epirubicin is normal.
3. The diet is mainly nutritious.
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I'll explain to you the problem of pathology.
Signet ring cell carcinoma has a high degree of malignancy and a poor prognosis.
ER PR is estrogen and progestin. HER-2 is an indicator of cancer cells that has a guiding role in prognosis.
On the issue of dosage, the statement of the cancer hospital should be accurate, according to the weight.
When it comes to supplementing nutrition, anything that is nutritious and high in protein will do. The key is that she can eat it.
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If you can, use the targeted drugs lapatinib or Hersedin.
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In the case of early-to-mid-stage triple-negative breast cancer, the biopsy results may not be completely accurate, which has a lot to do with sampling. Pathology should be preferably biopsied with a rough needle, and the nature should be determined before symptomatic examination**. Although surgery is the first choice of normal medicine, it still has its own problems.
Why are there metastases and ** after surgery? This is because the incision is a blind spot of the body's immunity, and cancer cells can often succeed if they hide here; The inevitable accumulation of tiny platelets during surgery protects the drifting process of cancer cells in the blood, escaping the hunt of strong human immunity, and many metastases or ** are only a matter of time. Chemotherapy and radiotherapy inhibit cancer cells and damage the body's immunity, weaken the body's physique, and reduce the recognition and striking power of immunity, creating conditions for metastasis.
Cases that resolve naturally tell people that more will not be **, which is the principle of hope. The enhancement of immunity is the fundamental direction of cancer, and the technology developed is worth paying attention to, activating the body's immunity to recognize cancer cells and then killing them is a good way, and the attention is.
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It belongs to the middle stage, this condition has a high degree of malignancy, is not sensitive to radiotherapy and chemotherapy, and endocrine ** is also ineffective, and it is recommended to combine it with others**.
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According to the pathological description, the current primary lesion is relatively small, and the effect of invasive ductal carcinoma is good, and most patients can be cured after active treatment.
Combination chemotherapy is recommended to use biological**, and the specific course of treatment should be determined according to the specific situation of the patient.
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Postoperative radiotherapy is not required, and the chemotherapy regimen is ECF for 6 cycles.
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1. The tumor is invasive, which means that your mother's pathology is not very early, but the size of the mass and the surrounding conditions can be regarded as early. There are less than 4 lymph nodes with metastases. According to the data, the 5-year survival rate is about 98% for local mass, 85% for axillary metastasis, and about 30% for distant metastases (NCI statistics).
Your mom probably falls into the second category.
2 Immunohistochemistry indexes, ER, PR are both positive, HER-2 negative, KI6715%. The typing is okay.
3 **: Surgery has been done, neoadjuvant chemotherapy is not considered.
1) Postoperative adjuvant chemotherapy: age 44 years old, the body should be able to choose, it is recommended to choose a drug regimen containing purple shirt drugs and anthracyclines. Time: 3 weeks program, 6 cycles. If the body is poor, you can change to the AC sequential T scheme, or you can do it.
2) Endocrine**: 44 years old, considering the possibility of menopause. After chemotherapy ends, oral endocrine drugs are started**. Tamoxifen is sufficient for 5 years. After 5 years, change the medication or continue to take it.
3) Radiotherapy**: According to the guidelines of NCCN, local radiotherapy can be considered if there are more than 4 lymph node metastases. Your mom is 2, and radiotherapy can be done or not. Talk to your doctor.
4) Immune enhancement**: Consider using drugs such as thymus peptides. Choose proprietary Chinese medicines carefully.
5) Regular review.
That's pretty much for that. It is recommended that you go to a large hospital or a hospital with a breast specialist.
Good luck to your mom and get back to health.
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"Lymph nodes can see cancer metastasis (2 13)", indicating that the patient's metastasis is good, and the diameter of the primary cancer is small, which belongs to breast cancer stage 2, that is, middle and early stage;
HER-2 negative, i.e., C-ERBB-2 negative;
ER PR is strongly positive, and it is recommended to adhere to endocrine for a long time after the completion of chemotherapy**;
The patient's condition is good, actively cooperates, and the clinical rate is very high.
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Personally, I think: first of all, his lump is not big, and the positive PR should have more options than the negative ** drug, she should belong to the early stage of breast cancer Thirteen two Many patients are about 20 and half!
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Breast cancer has been completely resected, but there has been regional lymph node cancer metastasis. Surgery should be followed by further chemotherapy . Available.
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I don't know how big your mother's removed lesions are, but this is at least the middle stage, not the early stage. The situation is okay, chemotherapy is required after surgery, and some traditional Chinese medicine can be used after chemotherapy. Hope to adopt, thank you...
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The immunohistochemistry results were good, and the stage was IIA.
Not a problem.
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The tumor is smaller, but the lymph nodes have metastasized, and the postoperative chemotherapy is combined with endocrine **, the chemotherapy regimen can choose 6 cycles of CAF or 8 cycles of AC sequential T regimen, I personally feel that 8 cycles are better, the course of treatment is longer, but the 3 chemotherapy drugs are separated to hit the patient and the pain will be less, and tamoxifen can be taken for 5 years after chemotherapy and secretion**.
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The pathological stage of your mother's coarse relatives is stage IIIA, there is metastasis in the lymph nodes, chemotherapy and Xiaoxian treatment must be done, the immunohistochemistry results are not bad, and you need to take endocrine ** drugs for 5 years.
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It is most important to adhere to the ** and maintain a good attitude, breast cancer is relatively easy **, and it will definitely get better.
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1. According to the pathological results, it can be seen that ER and PR are positive, and endocrine can be performed after chemotherapy**; However, HER-2 is also positive, which is prone to resistance to chemotherapy drugs, so Herceptin can be added if possible**. The drug can only be used in specific hospitals. And there are more than 20,000 drugs per drug, and there are almost 14 drugs for a patient.
2. If the lymph nodes are negative, it means that metastasis may not have occurred, but the malignant tumor is a systemic disease from the beginning, so chemotherapy is required. The patient had a better response than chemotherapy.
3. It is recommended to go to a regular hospital for regular chemotherapy and do not believe in false advertising.
Hope the above answers can be helpful to you.
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This situation is relatively optimistic, ER and PR are positive, and HER2 receptors are also positive, and many emerging methods for breast cancer can now be used, such as targeting, endocrine**, etc. Moreover, judging from the surgical results, it is a relatively early lesion, it should be T2N0M0, postoperative chemotherapy is sufficient, if necessary, radiotherapy can be added, and the 5-year survival rate is still very ideal.
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It's a pity, another early one was removed like this, why are they all questions after surgery, otherwise I can help you heal.
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Firstly, invasive ductal carcinoma is the most common type of breast cancer, and secondly, hormone blocking methods can be used according to the results of immunohistochemistry and positive ER PR**, and HER-2 (3+) indicates a poor prognosis, but now there are very good targeted ** drugs for HER-2-positive breast cancer.
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The prognosis of breast cancer should still be paid attention to, diet and daily life care need to be planned, and adhering to a healthy lifestyle habit all year round is responsible for one's body.
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The situation is good. ECF regimens were used for 4-6 cycles after surgery.
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Early detection and early diagnosis of the disease is the key to improving the efficacy. The diagnosis and differential diagnosis of breast cancer should be made in combination with the patient's clinical manifestations and medical history, physical examination, imaging examination, histopathological and cytopathological examination (in hospitals where available). Most patients come to the hospital by inadvertently discovering a breast lump, and a small number of patients are found to have a breast lump or suspicious lesion through regular physical examination or screening.
Palpable masses can be confirmed by needle aspiration biopsy or surgical excisional biopsy. If the clinical palpability of the mass is due to the detection of suspicious lesions by imaging examination, biopsy can be performed with the help of imaging examination, which is the gold standard for breast cancer diagnosis.
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Hello! For patients, receiving systematic monitoring and monitoring in a regular hospital after breast cancer surgery is the key to prevention. Especially in the first 5 years after primary breast cancer surgery, as long as conditions permit, you should insist on doing a complete set of ** in a regular hospital, and then follow the doctor's instructions for regular reexamination.
In addition to **, you should also get rid of some bad habits, such as smoking, alcoholism, high-fat diet, etc. I believe that as long as you have a positive and optimistic attitude towards life and fight cancer tenaciously, you will definitely achieve victory.
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It is good to use Chinese medicine for a month.
I don't think a particular diet or ingredient will have a significant effect on this. Of course, eating a balanced diet with plenty of vegetables and protein can help a lot.
Continue to take fluon orally. CerBB2 (++ Herceptin is not necessarily used, a FISH test can be done, and it is meaningful for positive patients. However, if you have no financial ability, you don't need to consider it.
For lymphedema, it can be taken orally to remove fat**, or it can be used as a blood circulation drive**.
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