What is the Valsalva maneuver and why does the Valsalva maneuver enhance the HCM murmur

The Valsalva test isTell the patient to perform a forceful breath-holding motionIt is a clinical physiological test that closes the glottis after deep inhalation, and then exhales forcefully, and fights against the closed epiglottis when exhaling, and affects blood circulation and autonomic function by increasing intrathoracic pressure, so as to achieve the purpose of diagnosis and treatment.

Cancer cells tend to use glycolysis to replace the aerobic cycle of normal cells, so cancer cells use mitochondria differently than normal cells. The phenomenon in which cancer cells mainly use glycolysis instead of the aerobic cycle is called the Valsalva effect.

This phenomenon has also aroused the curiosity of researchers, whether it can prevent the growth of cancer cells by guiding cells to restore normal aerobic circulation and cut off the energy of cancer cells**, so mitochondria and the process of regulating the aerobic cycle and glycolysis have always been important issues in cancer research.

Clinical significance:

By increasing intrathoracic pressure, the amount of venous return to the heart is significantly reduced; excitatory vagus nerve; Such as:

1) In paroxysmal supraventricular tachycardia, the vagus nerve is excited by the valsalva maneuver to terminate the onset of supraventricular tachycardia.

2) In hypertrophic obstructive cardiomyopathy, the murmur is enhanced by reducing the amount of blood returning to the heart through the valsalva maneuver, which is used to identify the murmur.

3) Mitral valve prolapse leads to mitral regurgitation, which enhances the murmur through the valsalva maneuver.

Valsalva maneuver: a closed-mouth breath test, in which the glottis is closed and forced to exhale to increase intrathoracic pressure.

This depends on what the sound is, generally speaking, there are the following two situations:

First, the sound of cannon fighting:

1. There is a discharge phenomenon (cleaning and drying) on the machine board.

2. Tail plug leakage (cleaning, drying).

3. The paper tray of the receiver is damaged or of poor quality.

4. Short circuit and leakage of flexible cable.

5. False welding and leakage of audio peripheral components.

Second, the sound of communication:

1. Leakage (rewelding) at both poles of the microphone.

2. Caused by replacing the poor quality casing (replacing the *** casing, or shielding with tin foil, but pay attention to it).

3. The transmitting power is too strong (add resistance to the transmission signal sampling line to reduce the power amplifier power).

valsalva maneuver

The above results are from Kingsoft Word Tyrant.

Web paraphrasing. 1.Valsalva action.

2.Valsalva action.

Hello. Your color ultrasound shows that you have moderate varicocele on both sides.

Varicocele has not been studied, and it is generally related to sitting time, standing for too long, strenuous exercise, trauma, and genetics.

Varicocele may affect the decline or loss of fertility function, and surgery is definitely required. Sun touches.