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Parkinson's disease, is a common geriatric disease, mostly in the elderly group, generally manifested as slow mobility, memory loss, do not remember their family, do not remember the number and what their name is, but also accompanied by a certain sleep disorder, irritability and anxiety, often feel very low, some do not even know the basic object, is a common neurodegenerative disease, in the age of 30 people are relatively rare, ** is more complicated, because every family has the elderly, We don't want our elderly to suffer from Parkinson's disease, in order to avoid irreversible damage caused by this disease, if you find that the elderly at home have these symptoms, you should go to the hospital as soon as possible, then let's find out what are the main ** of Parkinson's disease? <>
First, genetic causes
If someone has Parkinson's disease in the family history, then people with this genetic background have a higher probability of getting Parkinson's disease than ordinary people, its incidence is relatively high, and it is also the only neurodegenerative disease that can be the first.
Second, the causes of chronic diseases
If the patient usually has some chronic diseases, such as brain trauma, cerebral infarction, encephalitis, etc., these diseases will cause Parkinson's disease, because it is a secondary disease, the previous chronic disease will destroy the brain, we all know that dopamine is very important, if the brain black mole is destroyed, the dopamine synthesis in the human body will be reduced, then it will be destroyed, resulting in certain neurological dysfunction. <>
Third, there is a lack of communication with the outside world
The elderly are more lonely, retired, there is nothing to do at home, social life is relatively less, children often go home to visit the elderly, people without thinking, the brain will run slower, if you usually go out to exercise, listen to **, make more friends and travel more, the probability of Parkinson's disease will be relatively low, in fact, the best filial piety is not to give the car to the house, but to always be with the parents, talk to them, take them around. <>
The above are some of the causes of Parkinson's disease, and I hope you can get some inspiration from them to avoid the occurrence of Parkinson's disease.
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Regarding Parkinson's disease**, it is currently believed that Parkinson's disease is caused by a combination of genetic factors and environmental factors. At present, many single-gene mutations have been found in the study of Parkinson's disease, such as the parkin gene and the -synuclein gene, which can cause Parkinson's disease. This type of patient has an early onset of disease and is called early-onset Parkinson's disease.
Another 90% of patients do not find an inherited single gene, called sporadic Parkinson's disease. Although no single gene has been found to cause sporadic Parkinson's disease, genes still play a role. The main genre is the external environment, like pesticides, the most typical substance is called MPTP, which is the factor that causes Parkinson's disease.
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Trembling fingers, dizziness, memory loss, paralysis of the lower body, dystonia, mental retardation, speech disorders, depression, insomnia at night are all symptoms of Parkinson's disease. It may be due to some medication or a viral infection, or it may be caused by trauma.
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It is very likely that it is because of taking the wrong medicine, or it is also due to poisoning, contracting some diseases, receiving some trauma, in short, there are many reasons.
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In fact, from the perspective of clinical medicine, age factors and environmental factors are the main causes of Parkinson's disease, and the prevalence of Parkinson's disease will increase with age.
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The cause of Parkinsonism is due to the degeneration of brain cells, resulting in insufficient secretion of dopamine neurotransmitters, which causes the dopamine rotamine function to be affected, and the acetylcholine function is deficient.
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Parkinsonism can usually have the following**
1.Aging is one of the most common causes. The prevalence of PD varies with age, and glutathione peroxidase and catalase decrease during aging and PD. With age, monoamine oxidase increases, iron, copper, calcium aggregates, and melanin aggregates.
Incidence increases with age.
2.Genetic factors, genetic mutations can lead to degeneration and death of neurons, and if the striatum nigra is affected, Parkinsonism will occur.
3..Trauma, traumatic brain injury can also lead to Parkinsonism.
4.Cerebrovascular disease, poisoning, encephalitis, drug abuse, etc. are also the most important aspects of Parkinsonism.
5.Environmental toxicants: Manganese poisoning, carbon monoxide poisoning, phenothiazine, and butyrylbenzene have long been noted to produce PD symptoms.
6.There are also neurodegenerative diseases, such as multiple system atrophy and corticobasal degeneration, that can also cause parkinsonism.
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Parkinsonism refers to the symptoms similar to Parkinson's disease such as resting tremor, bradykinesia, and muscle rigidity caused by some **, and the common causes of Parkinsonism include cerebrovascular disease, degeneration, infection, poisoning, drugs, etc. Some factors that cause parkinsonism are reversible, such as an overdose of antipsychotics, antidepressants, or long-term use, which can cause parkinsonism, and the symptoms will gradually disappear after stopping the drug. However, most of the Parkinson's syndrome, such as cerebrovascular disease, degeneration, infection, poisoning, etc., are irreversible and extremely difficult.
Unlike Parkinson's disease, levodopa does not respond well to Parkinsonism. Sometimes primary parkinsonism and parkinsonism can be difficult to distinguish between and can be distinguished by careful history.
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Many people don't know about Parkinson's disease, which is actually a common central nervous system degenerative disease in middle-aged and elderly people. It is very harmful to the patient, and knowing the ** of this disease can help prevent and treat it. So, what are the common ** of Parkinson's disease, the following is a specific introduction.
1. With the increase of age, the number of dopamine neurons in the brain decreases, and their functions are also declining. The decrease in dopamine in the brain in Parkinson's patients is much higher than normal levels of aging. This shows that aging is also one of the common diseases of Parkinson's disease**.
2. Parkinson's disease is caused by damage to dopamine neurons in the brain. Studies have found that the patient's dopamine in the brain is reduced, and the organic combination of various organs in the body cannot be controlled, resulting in trembling hands and feet, and unstable holding.
3. Genetic factors, mainly genetic susceptibility genes. Data show that people with Parkinson's disease in their families are 2-3 times more likely to get sick than ordinary people, and the causes of diseases such as brain sclerosis and brain damage lead to Parkinson's disease induction.
4. Chemicals such as drug abuse, pesticides, pesticides, etc. are all factors that cause Parkinson's. Surveys have found that long-term exposure to substances similar to the molecular structure of MPTP is associated with a higher risk of developing Parkinson's disease. The disease is the result of a combination of causes.
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The causes of Parkinson's disease are generally related to genetics, diffuse brain damage caused by poisoning, adverse reactions to taking antipsychotic drugs, viral infections, cerebral arteriosclerosis caused by aging of the nervous system, cerebrovascular diseases such as multiple cerebral infarctions, traumatic brain injury, intracranial space-occupying lesions, parathyroid dysfunction and other factors.
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The main causes of Parkinson's disease are mostly due to hereditary factors, brain damage, and long-term life and work under the regulation of heavy metals.
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The medical community now believes that Parkinson's tremors may be caused by genetic factors, which means that Parkinson's disease has a certain genetic predisposition, and if there is a Parkinson's disease among close relatives, then it is more likely to develop the disease than those who do not have this disease in close relatives.
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Parkinson's disease, which is caused by neuropathy in the body. Causing his body to tremble constantly.
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Medications are the most common cause of secondary parkinsonism. Neuroleptics (phenothiazines and butyrylbenzenes) used for psychiatric disorders are the most common causative drugs. It is important to note that sometimes we also use these medications** for non-psychiatric conditions such as vomiting, such as promethazine for anti-emetic conditions.
Others can cause or worsen Parkinsonism.
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Synthesis. What causes Parkinson's disease? No one can say what this has caused, and there are no classes in medicine now. It's the human brain. This is the cause of the degeneration of the human brain.
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Parkinson's is a common degenerative disease of the nervous system in old age.
In addition to following the doctor's instructions and taking symptomatic medication, it is recommended that: first, assist in mental health care and develop a peaceful and calm state of mind; The second is to assist in dietary life, pay attention to comprehensive nutrition in the diet, especially pay attention to the intake of goose eggs, nuts, carrots, loofahs, wolfberries, jujubes and other foods that use cranial nerves.
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1. Environmental elements. Environmental factors are the cause of Parkinson's disease in the elderly, and the key to prevention is to start from the natural environment. More than a decade ago, biologists discovered that a compound, MPTP, can cause typical Parkinson's disease in humans and their small animals.
Not only are the symptoms completely similar, but the pathology of Parkinson's disease caused by this compound is also very similar to that of human Parkinson's disease from the changes in the pathological structure and medical record. 2. Cerebral arteriosclerosis: Parkinsonism can occur when multiple lacunar cerebral infarctions occur in the spinal cord and basal ganglia caused by cerebral arteriosclerosis, which affects the substantia nigra dopamine striatal channel.
However, most of these patients have pseudobulbar palsy, hyperreflexia, and positive pathology, and often have significant Parkinson's disease, which is also the cause of geriatric Parkinsonism. 3. Genetic elements. Parkinson's disease can be inherited genetically, so genetic elements are also the cause of elderly Parkinson's disease, but the proportion of genetic elements is not very large.
I firmly believe that with the in-depth analysis of genes, we will have a deeper grasp of the expression of genes and the role of proteins, and we are still looking forward to the treatment of medicines, the treatment of the causes of diseases, and the treatment of genes. Genetic elements account for about 10% of the chance of Parkinson's disease.
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Genetic factors. It is thought that 10% of patients have a family history, and the vast majority of patients are sporadic. Segments and.
Environmental factors. Industrial or agricultural toxins in the environment that are similar to the neurotropic 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) molecular structure, such as certain pesticides, herbicides, rotenone, etc., may be one of the most important causes of Parkinson's disease.
Aging of the nervous system.
Some data show that after the age of 30, with age, substantia nigra dopaminergic neurons begin to show degeneration, but not all of them lead to Parkinson's disease, aging is the most important factor in the occurrence of Parkinson's disease.
Multi-factor interactions.
With the exception of a small number of people with familial Parkinson's disease, genetic susceptibility increases the likelihood of developing the disease, but it does not necessarily lead to the disease.
It is due to the combined effect of environmental factors, aging of the nervous system and other factors that will lead to the onset of the disease.
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Parkinson's is a common disease in the elderly, the early symptoms are common with tremors, and the consequences are more serious, which can lead to the patient's disability and inability to take care of himself, ** It is not clear at present, and the common factors include: 1. Genetic factors: the patient has a susceptible constitution; 2. Stuffy hands and dry environmental factors; 3. Biochemical factors; 4. Drug-induced factors:
It is often inappropriate to use antolamine drugs, such as morpholine, metoclopramide and other gastrointestinal drugs, sedative drugs, and antidepressants; 5. Physical and chemical factors; 6. Pesticide poisoning.
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It is caused by the degeneration of the striatum nigra in the brain and a significant decrease in the amount of dopamine in the brain. There are also drugs, trauma or infections.
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That's a complicated question! Let me tell you, many people who suffer from this disease nowadays are usually elderly! It should be based on a mutation or a neurological problem! If there is no way to **! The causes of blight disease are complex! You try it!
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Many are caused by trauma.
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1. Primary Parkinson's disease. It is generally believed that primary Parkinson's disease is a degeneration of nerve cells, and the main lesions are in the substantia nigra and striatum. There is a kind of nerve cell called substantia nigra cells, and the degeneration of nerve cells here refers to the gradual decrease in the number of substantia nigra cells, the gradual decline and loss of function, resulting in a decrease in dopamine in the brain, thus causing symptoms of Parkinson's disease.
2. Secondary Parkinson's disease. Secondary Parkinson's disease is mostly caused by infection, poisoning, drugs, trauma, etc.
1) Infection: encephalitis, lentiviral infection, etc. may cause secondary Parkinson's disease.
2) Poisoning: Poisoning caused by exposure to MPTP, carbon monoxide, manganese, mercury, carbon disulfide, methanol, ethanol and other poisons may also lead to secondary Parkinson's disease.
3) Drugs: Neuroleptics for psychiatric diseases such as phenothiazines and butyrylbenzene are the most common pathogenic drugs that may cause Parkinson's disease.
4) Trauma: such as traumatic brain injury, boxing encephalopathy, etc., may also cause secondary Parkinson's disease.
In addition, vascular diseases such as cerebral arteriosclerosis, multiple cerebral infarction, and other diseases such as thyroid dysfunction and positive pressure hydrocephalus may also cause secondary Parkinson's disease.
3. Hereditary Parkinson's disease. According to the results of animal experiments and epidemiology, it is also believed that Parkinson's disease has a certain relationship and connection with heredity. It can be seen in diseases such as Wilson's disease and dopa-responsive dystonia.
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