What should be the temperature of the medicine in the freezer in the cold chain

Legal analysis: drug storage conditions should have a warehouse that classifies drugs and meets the requirements of drug storage. Among them, the temperature of the normal temperature storage is 0 30, the temperature of the cool storage is not higher than 20, and the temperature of the cold storage is 2 10; The relative humidity of each warehouse should be maintained between 45 and 75%.

Legal basis: Drug Administration Law of the People's Republic of China

Article 2 This Law shall apply to those engaged in the development, production, distribution, use, supervision and management of drugs within the territory of the People's Republic of China.

The term "drugs" as used in this Law refers to substances used to prevent, diagnose and diagnose human diseases, purposefully regulate human physiological functions, and stipulate indications or functional indications, usage, and dosage, including traditional Chinese medicine, chemical drugs, and biological products.

Article 3 Drug management should be centered on people's health, adhere to the principles of risk management, whole-process control, and social co-governance, establish a scientific and strict supervision and management system, comprehensively improve the quality of drugs, and ensure the safety, effectiveness and accessibility of drugs.

Legal analysis: The drug storage conditions required by GSP certification should include classified storage of drugs and warehouses that meet the storage requirements of drugs. The storage temperature is 0°C to 30°C, the refrigeration temperature is not higher than 20°C, and the refrigeration temperature is 2°C to 10°C

Legal basis: Article 49 of the "Good Practice for Pharmaceutical Operation" shall be equipped with the following facilities and equipment for the storage and transportation of refrigerated and frozen drugs:

1) Cold storage suitable for its business scale and variety, and the storage of vaccines shall be equipped with more than two independent cold storage;

2) Equipment for automatic monitoring, display, recording, regulation and alarm of cold storage temperature;

3) Standby generator sets or dual-circuit power supply systems for cold storage refrigeration equipment;

4) For drugs with special low temperature requirements, facilities and equipment that meet their storage requirements shall be equipped;

5) Refrigerated trucks and vehicle-mounted refrigerators or incubators and other equipment.

The temperature is between 2-48 degrees.

The drug refrigerator is a new intelligent multi-functional incubator, with a wide range of temperatures between 2-48 degrees, and the required value can be set arbitrarily, with a temperature difference of 2, especially suitable for medical, health, epidemic prevention, food and chemical industry, military industry, scientific research and other departments.

In the case of more stringent refrigeration requirements, the need to use compressor to consume energy to achieve the purpose of accurate refrigeration refrigeration refrigerators, according to different needs, are divided into high-temperature refrigeration type, room temperature refrigeration type and low-temperature refrigeration type refrigerated cabinet.

For drugs that require to be placed in a cool place or refrigerated, they need to be put in the refrigerator as required, but some drugs are not required to be placed in the shade or refrigerated, and some people think that putting them in the refrigerator will keep them fresh like food, so that the effect of the medicine will not be lost. In fact, this idea is wrong, it is not written that it cannot be stored in the refrigerator if it is refrigerated and stored in the shade. For example, the following medicines should not be stored in the refrigerator.

1. Syrup preparations: such as cough syrup, cold syrup, etc., because most of the syrups will reduce the solubility of the drug at too low temperature, resulting in a decrease in drug concentration and reduced efficacy, so it is not suitable for storage in the refrigerator.

2. Cream: At too low a temperature, the external cream will cause matrix stratification, affect the uniformity of the ointment, and reduce the efficacy.

3. Valuable traditional Chinese medicine: such as ginseng, deer antler velvet and other traditional Chinese medicine generally need to be stored dry, and the humidity in the refrigerator is conducive to the growth and reproduction of bacteria, which will make the traditional Chinese medicine deteriorate, lose its efficacy, and even appear.

There are also differences in the storage temperature of different kinds of medicines, some are stored at about 20 degrees Celsius at room temperature, and some are stored at low temperatures. In particular, biologics such as vaccines require very strict temperatures, mostly for cryopreservation. The temperature of the refrigerator compartment is suitable for the requirements of cryogenic storage.

Each drug that has storage requirements will be explained in the instructions, so you can adjust the refrigerator compartment to the appropriate storage temperature according to the instructions!

The temperature of the refrigerator is between 2 and 48 degrees.

Suzhou Hisiyuan.