Ask for help from well wishers! About duodenal diseases with Helicobacter pylori

You take amoxicillin + tinidazole for three months.

Helicobacter pylori causes duodenal ulcers. @ Rapid treatment of ulcers: 2 tablets of dysentery + 2 tablets of vitamin B6, 2-3 times a day. Eat for 2 weeks**. The child reduces.

HP is a spiro-spirobacterium that can migrate to the gastric mucosa in various ways, free in mucus, adhere to the surface of the stomach and between cells, causing a large degree of mucosal damage. At present, it is believed that the formation factors of gastric ulcer are more focused on the weakening of the gastric mucosal barrier and the increase of gastrin secretion, while the formation factors of duodenal ulcer are more focused on the overall enlargement of parietal cells. Symptoms of gastric ulcers are often atypical, and can manifest as epigastric pain and epigastric discomfort.

Most people can experience various symptoms of dyspepsia, but some have no symptoms until complications occur. Common complications include hemorrhage, perforation, pyloric obstruction, and cancer. At present, its ** and epidemiology have not been fully clarified, and it is known that the equilibrium between ulcerogenic factors and anti-ulcer protective factors in normal people is in a dominant state of the latter.

Peptic ulcer disease can occur if ulcerogenic factors are increased and/or antiulcer protective factors are weakened. If this balance is disrupted over time, the ulcer becomes chronic.

In 1982, Marshall et al. cultured Helicobacter pylori (HP) from human gastric mucosal biopsy specimens, combined with gastroscopy, proposed that the bacterium was closely related to the pathogenesis of gastritis and peptic ulcer, which attracted the attention of the medical community, and after 10 years of research, it has been confirmed that Helicobacter pylori infection is an important factor causing ulcer disease. Since Warren and Marshall reported HP, the relationship between peptic ulcer and HP has been highly valued by scholars at home and abroad. There is a clear correlation between HP and gastric ulcers.

According to the data results, there was no significant difference in the rate of HP infection between chronic superficial gastritis and chronic atrophic gastritis, and atrophic gastritis was slightly higher than that of superficial gastritis. The rate of HP infection in follicular gastritis is extremely high, and +++ is the majority, suggesting that HP infection is closely related to lymphoid tissue proliferation. Gastric ulcer is mostly accompanied by gastritis, and the positive rate of HP is significantly higher than that of gastritis alone, which indicates that ulcer disease can develop from gastritis, and also proves that HP is one of the most important elements of ulcer disease, and HP infection is positively correlated with its degree and condition.

HP positivity is the main reason for the activity and progression of gastric disease, HP conversion is a sign of disease healing, and HP clearance is the key to HP-related diseases and prevent them. There were no significant differences in HP positivity rates by gender or age. The rate of HP positivity is slightly higher in older adults aged 60 years and older than in those under 60 years of age.

Among the commonly used HP examination methods, microscopic examination of tissue section staining is intuitive and accurate, and does not need to add tissue in addition to pathological biopsy. The methylene blue staining method we used was compared with silver staining and HE staining. It is considered that it is simple and convenient, the contrast between bacteria and tissue staining is obvious, and the curved and S-type Helicobacter pylori can be clearly identified by universal light microscope observation, which is worthy of popularization and application.

Helicobacter pylori can cause duodenal ulcers. Duodenal ulcer is similar to gastric ulcer, which is caused by tissue damage beyond the muscular layer of the mucosa caused by the digestion of the intestinal mucosa by digestive juices.

Traditional Chinese medicine introduces a recipe: Changbai Yam Valley clove tea.

The unique clove oil and eugenol of clove tea can effectively inhibit the activity of Helicobacter pylori, so as to achieve the effect of inhibiting and killing Helicobacter pylori.

It is very important to kill Helicobacter pylori, and brewing 3-5 grams of clove leaf tea every day is very good for the stomach. Especially Changbai Yam Valley clove tea, I drink it a lot.

At present, the following regimens are commonly used for Helicobacter pylori:

1.Proton pump inhibitors (English abbreviation "PPI", commercially available such as omelachizole, lansoprazole, etc.) + two antibiotics: PPI standard measurement + amoxicillin clarithromycin, both twice a day, 1 week as a course of treatment; PPI standard measurement + amoxicillin metronidazole, twice a day, 1 week as a course of treatment; PPI standard measurement + metronidazole clarithromycin, both twice a day, 1 week as a course of treatment.

2.Bismuth: Livzon stomach triplet:

It is composed of two antibiotics, bismuth (Livzon Dela), which is a very effective drug for Helicobacter pylori at present, with a course of seven days and a rate of more than 90%; Bismuth + two antibiotics: standard dose of bismuth (Livzon Dele Wubi is recommended) + amoxicillin metronidazole, twice a day, 2 weeks as a course of treatment; Bismuth (recommended Livzon Dela) standard dose + tetracycline metronidazole, twice a day, 2 weeks as a course of treatment; Standard dose of bismuth (Livzon Dela) + clarithromycin metronidazole, twice a day for a course of 2 weeks.

3.Other regimens: Ranitidine bismuth citrate (RBC) is used to replace the receptor antagonist H2-Ra in Recommended Regimen 1) or PPI + Recommended Regimen 2 to form a quadruple** for one week. Metronidazole in the regimen can be replaced with tinidazole.

Prevention of H. pylori infection is essential. Pay attention to personal hygiene, such as gargling after each meal, eating separately, washing vegetables and fruits, etc., to minimize the chance of infection.

Hello, judging from your symptoms, it is estimated that there is a high probability that Helicobacter pylori does not have **, it is recommended that you can also take rabeprazole at present, plus giffamate to try, if the symptoms can be completely relieved, it is recommended that you gradually reduce the dose of rabeprazole and stop. Generally, ulcer disease is not easy to attack in the summer, it is recommended that you stop taking the drug for a month at that time, and do a breath test, if it is positive, it is recommended that you follow **, and then you can come to the outpatient clinic to see me.

Peking University Hospital Cheng Hong Ying Chong.