What is the pathogenesis of thrombocytopenic purpura? What kind of hypersensitivity reaction is it?

Platelets mainly play hemostatic coagulation function, low platelets will have the possibility of spontaneous bleeding, mild is subcutaneous bleeding, that is, **purpura, or gum bleeding, nosebleed, serious visceral bleeding or intracranial hemorrhage, is life-threatening. The root cause of this disease is the defect of the body's immune mechanism, and the onset of the immune system is caused by the imbalance of the immune system, which is also known as immune thrombocytopenia in medicine.

There are many predisposing factors for this disease, including chemical poisons, radiation, ionizing radiation, injection vaccines, inflammatory virus infections, drugs, overwork, etc., these factors can only be speculated, and it is not certain what causes them. The important thing is how to cure the root cause and not repeat it, and if it is cured, it will not be affected by any factors and repeated.

Henoch-Schonlein purpura, also known as self-limited acute hemorrhage, is a kind of allergic vasculitis that invades arteries and capillaries of ** and other organs, and the cause may be pathogen infection, certain drug effects, allergies, etc., resulting in the formation of IgA or IgG circulating immune complexes in the body, which are deposited in the capillaries of the upper dermis and cause vasculitis.

Answer]: A Idiopathic thrombocytopenic purpura is an autoimmune disease, mainly due to the binding of autoantibodies to platelets, resulting in shortened platelet survival and leading to bleeding. The clinical characteristics of Henoch-Schonlein purpura (articular type) are the swelling and pain of the knee, ankle, elbow and wrist joints before and after the appearance of **purpura, with the pain and swelling of the knee joint being the most significant, which can be in a migratory state and reversed.

Therefore, 17 questions are selected B, and 18 questions are selected A.

Answer]: B Idiopathic thrombocytopenic purpura (ITP) is an acquired bleeding disorder of unknown cause, characterized by thrombocytopenia, normal or increased megakaryocytes in the bone marrow, and absence of any cause. The incidence of chronic ITP in women of childbearing age is higher than that in men, and the incidence of chronic ITP is higher in women, and it is easier to lift in pregnancy**, suggesting that no estrogen may be involved in the pathogenesis of ITP.

Thrombocytopenic purpura is caused by thrombocytopenia, and allergic purpura is caused by a certain allergy, and there is a difference in **.

Answer]: A analysis: Henoch-Schonlein purpura is caused by abnormal blood vessel walls, and the diseases caused by decreased platelet count or abnormal function include primary platelet purpura, aplastic anemia, and congenital platelet weakness; Diseases caused by low coagulation factor desensitization chains or lack of hand thickness include hemophilia and vitamin K deficiency.