Can transaminase lowering and antiviral therapy be done at the same time?

1. In terms of the degree of elevated aminotransferase, the antiviral effect will not be very good, generally more than twice the normal standard value, because the degree of liver damage is related to the level of autoimmunity, and your liver damage is not serious, indicating that the body's immunity to hepatitis B virus is not very strong, but there is a situation that can be considered with antiviral drugs, that is, repeated hepatitis activities, perennial aminotransferase mildly increased, or liver biopsy shows severe or progressive fibrosis, then active countermeasures should be taken.

2. The main role of Ganlixin is to lower enzymes and protect the liver, but I personally think that the former has a stronger effect. If it is used in combination with antiviral drugs, it is not too big to use it with lamivudine, but it is best not to use it with interferon, because Ganlixin has a hormone-like effect, that is, it has a certain immunosuppressive effect and antagonism with interferon.

3. The landlord's aminotransferases are not too high, except for the situation I mentioned, antiviral is generally not recommended, and even if antiviral is chosen, Liver Lixin does not have to be taken at the same time, because transaminases are 10 units high and do not have to be busy lowering enzymes.

The method of hepatitis in Western medicine is to kill the hepatitis B virus with direct medication, which damages the liver cells while killing the hepatitis B virus.

There are many patients who have used up Western medicine for a year and their liver function is normal, but once they do B ultrasound, the liver fibrosis is serious and they enter early cirrhosis. Pay attention to taking Western medicine such as lammy: do liver B ultrasound examination regularly, because Western medicine will interfere with the test results, false positive or hidden hepatitis B, and B ultrasound will only find liver structure lesions.

Yes and not contradictory.

Antiviral will speed up the recovery of liver function.

Your current situation does not recommend that you use drugs indiscriminately, and it cannot be just a single antiviral**, which can easily cause the virus to mutate.

It is recommended that you can use the method of three-yang division to prescribe medication symptomatically.

There have been countless precedents for accelerating liver damage after being antiviral. If you don't believe me, you can try it.

It is recommended that you use Chinese herbal medicine** for good results.

General indications for antiviral** [39-42].

General indications include: (1) 105 copies of HBV DNA in mL (104 copies mL in HBEAg negative patients); (2) ALT 32 times the upper limit of normal; If interferon** is used, ALT should be 10 times the upper limit of normal and total blood bilirubin level (TBIL) should be < 2 times the upper limit of normal; (3) If ALT < 2 times the upper limit of normal, but liver histopathology knodell hai 4, or moderate (G2 3) and above inflammatory necrosis and or moderate (S2) or above fibrotic lesions.

Patients who do not meet the above criteria should be monitored for changes in their condition, and antivirals should also be considered if they are persistently HBV DNA positive and ALT abnormal

Care should be taken to rule out elevated ALT due to drugs, alcohol, and other factors, as well as transient normality of ALT after enzyme-lowering drugs. In some special diseases, such as cirrhosis, the AST level may be higher than that of ALT, and the AST level may be used in such patients.

Hepatitis B virus as an infectious, and can harm kidney function, has been widely concerned by the medical community, but due to the existence of hepatitis B vaccine, the incidence of hepatitis B virus has been greatly reduced, but it can not be eliminated caused by hepatitis B patients, the whole process of treatment of hepatitis B patients is also worthy of our attention, as far as the topic of eating meat is concerned, many people think that hepatitis B patients cannot eat meat, and feel that eating meat will aggravate their physical condition, so can hepatitis B patients eat meat? If so, what kind of meat is suitable for people with hepatitis B?

Can people with hepatitis B eat meat?

In this regard, it is best to separate meat from fat, although meat is the vast majority of the medium of fat, but there is a difference here, for hepatitis B patients, taking too much fat is not good for the disease, because too much fat will cause blood viscosity, so it will harm the physical and mental health of the liver and high efficiency, so it will give the hepatitis B virus a higher chance, but meat, especially meat with less fat content, is basically not easy to cause harm to hepatitis B patients, Moreover, the general lean pork has a variety of protein, which is very beneficial to the hepatitis B virus group to supplement protein and improve the body's immunity.

For example, what kind of meat can a person with hepatitis B eat?

Black-bone chicken. Black-bone chicken is different from ordinary chickens, originally in the chicken thigh meat, the fat content is relatively lower than that of raw pork, and the fat content of black-bone chicken is getting less and less, especially suitable for hepatitis B virus group, at the same time, black-bone chicken has the actual effect of clearing liver fire, tonifying kidney and aphrodisiac, reducing fever, regulating qi and blood in traditional Chinese medicine, and has certain benefits for hepatitis B patients whose liver function is affected. In addition, the protein in the human body of black-bone chicken is also greater than that of ordinary chickens, and it can have some unexpected practical effects after a long time.

Pigeon meat. Young pigeons can be said to be a symbol of high concentration is the essence of the young pigeon, the nutritional value often contained in the young pigeon, much higher than other birds, folklore is also a "pigeon is better than nine chickens" point of view, the fat content of young pigeons, compared to other trace elements occupancy, only occupies 1% or so, if you can boil, steamed and other very physical and mental health cooking methods to do, you can make the nutrients retained more sufficiently, the same is very conducive to the nutritional supplement and physical condition repair of hepatitis B patients, At the same time, the nutrients in pigeon eggs are as rich and colorful, and often taken can have the practical effect of maintaining the nervous system.

Sardine. Sardines belong to freshwater fish, not only in which the protein content is very high compared to other fish, at the same time, sardines are rich in unsaturated fatty acids, unsaturated fatty acids can reasonably inhibit the excessive production of carbohydrates, long-term consumption can effectively reduce the accumulation of body fat, in addition, in traditional Chinese medicine, sardines have the actual effect of treating liver stagnation and qi stagnation, and are very helpful in maintaining the kidney physical and mental health of the hepatitis B virus group.

It's not like that, even if it is doubled, it can be **, but the risk is relatively large, and the effect is not very good.

This is not the case, as long as the aminotransferase is greater than twice the normal, antiviral can be administered**.

Antiviral therapy is indicated when liver function is abnormal, aminotransferases are elevated to more than twice normal, and viral replication is positive.

Mr. Zhao is 36 years old and has been suffering from chronic hepatitis B for more than 10 years. Soon after I went to the hospital for an examination, the indicators showed that the aminotransferases were elevated, and the doctor recommended that he be antiviral**, just when he was struggling with whether to be antiviral, his friend said that it had not been increased to 2 times, so there was no need to go**. Once you drink the antiviral medicine, it will be a lifetime, and you can usually regulate and recuperate, and you don't need to listen to the doctor's scare.

So Mr. Zhao followed his friend's advice and took enzyme-lowering drugs.

Here I would like to say that the enzyme drug is only an auxiliary effect, it cannot reduce the replication of the virus at all, and cannot inhibit the reproduction of the virus. However, some people directly use enzyme-lowering drugs when aminotransferases are elevated, and stop using them when aminotransferases are normal, which will accelerate the development of liver cirrhosis and liver cancer, so it is not advisable.

For hepatitis B patients, we do not have to wait for transaminases to increase by 2 times before they can be antiviral**, for the sake of health and safety, we can do antiviral when transaminases are greater than 1 times the upper limit of normal**. Patients with abnormal liver function aminotransferases should first be closely observed, and continuous monitoring of aminotransferases should be carried out for a week, and if the aminotransferases are persistently elevated, antiviral drugs must be used.

What should we do to prevent elevated aminotransferases?

1.On the wagon. Regular alcohol consumption can damage our liver cells, leading to further elevation of aminotransferases, and hepatitis B patients will slowly turn into cirrhosis and even liver cancer under the impetus of alcohol.

2.Stay up late. Staying up late can also cause an increase in aminotransferases, and when our liver has problems, staying up late is also to be avoided, staying up late hurts the liver.

3.Diet. In daily life, we should also pay attention to our diet, and a reasonable combination can be more healthy.

1. All hepatitis B belongs to viral hepatitis, chronic hepatitis, and liver disease, but the incidence is high and the infectivity is strong, and the liver disease itself is accompanied by chronic liver damage. Otherwise, long-term antiviral drugs**, even if the virus is controlled, it is also superficially controlled, and the liver damage has not been reduced at all, and the cost is high, the risk is high, and the disease will be aggravated once drug resistance occurs.

In most cases, the higher the transaminase, the more severe the liver damage, but the transaminase is normal, which cannot be completely equated with normal liver function.

Therefore, don't simply understand that as long as the transaminase is reduced, it is to restore liver function, simply reduce the transaminase, after stopping the drug, the real way to reduce transaminase is to restore liver function, after the liver function is restored, if it is viral, the virus index will slowly decline, **It is recommended to use traditional Chinese medicine, you can use Chinese patent medicine such as Liuwei Wuling tablets**, at the same time, you need to pay more attention to rest, correct your bad life and eating habits, such as quitting alcohol, appropriate exercise, Eat a balanced diet with foods high in protein, fruits and vegetables.

**Course of treatment: The first three months are a course of treatment, recheck the liver function and virus number, and after the liver function is normal, the liver function and virus indicators can be rechecked once every six months. If it can turn negative, after turning negative, after consolidating for half a year, the drug can be stopped, and if it cannot turn negative, the dose can be gradually reduced.

Hello, the elevation of aminotransferases proves that the hepatitis B virus replicates relatively quickly, and hepatitis B antiviral drugs are needed at this time.

Liver protection and enzyme-lowering drugs are used first, and it is best to go to the hospital system**.

, total bilirubin 22, HBV-DNA.

This condition is prevalent in the antiviral process, and many people with hepatitis B tend to experience a period of elevated aminotransferases in the initial stages of antiviral treatment. Most people believe that in the process of anti-virus, if the HBV-DNA regularity decreases or does not **, but the aminotransferase increases, the reason may be that the virus itself has an inhibitory effect on the body's immune function, once the virus is inhibited, the inhibitory effect of the virus on immunity is eliminated, thereby improving its own immune function to explain. (Excerpt from ".

Hepatology digest) We used to have a misconception about hepatitis, thinking that normal aminotransferases meant that the inflammation was under control. Before lamivudine was marketed in 1999, the main means of hepatitis B in China was the so-called hepatoprotective drugs, which treated the symptoms but not the root cause, one-sided pursuit of normal aminotransferases, and ignored the most fundamental antiviral in hepatitis.

At present, experienced doctors in China will not recommend patients to take enzyme-lowering and hepatoprotective drugs without special circumstances, because: first, taking enzyme-lowering hepatoprotective drugs deliberately interferes with the metabolism of ALT (alanine aminotransferase) and reduces the level of serum ALT, which only reduces the value on the test sheet, which is not beneficial to the inflammation and function of the liver itself. Instead, it will produce the illusion of normal ALT, which will interfere with the accurate clinical assessment of the condition.

Secondly, we should carefully consider that any drug will increase the burden on the liver, thereby causing or aggravating liver damage. Especially some traditional Chinese medicine and folk home remedies, secret recipes, etc., although China has accumulated a lot of experience in traditional Chinese medicine ** hepatitis, but the composition and mechanism of traditional Chinese medicine are too complex, which is likely to aggravate the damage to the liver.

Finally, from a patient's economic point of view, we also do not recommend taking enzyme-lowering and hepatoprotective drugs. Antiviral** is a long-term process, and the current domestic interferon and nucleoside analogues are not very low, so it is not recommended that patients bear hepatoprotective ** without practical effect.

Of course, in the event of persistent liver damage, the doctor should consider whether to perform liver protection** at his or her discretion. After all, each patient has its own particularities, and whether it should be hepatoprotective or not** needs to be treated differently.

Friend, you have an elevated aminotransferase in the middle of the antiviral**, and this depends on what regimen you use.

Aminotransferases are originally present in liver cells and are released due to liver cell damage or death, so we have blood drawn to detect elevated aminotransferases. And your liver cell damage is mainly caused by the hepatitis B or hepatitis C virus, so theoretically, as long as the virus turns negative, the aminotransferases are normal. However, there are other factors to hepatocellular damage besides the viral factor:

If you don't rest well, it is possible to have a viral infection (cold) or a high-fat diet that increases the burden on the liver.

If we only consider the problem of liver disease viruses, then different antiviral regimens may also appear in your case:

1. Use interferon**. Interferon can be antiviral and modulating immunity. It is for this reason that many hepatitis B and C patients** have become more and more fierce in their fight against the virus because their autoimmunity is activated, resulting in an increase in aminotransferases.

2. Nucleoside analogues. Nucleosides do not have immunomodulatory effects. However, in general, hepatitis B is at least 80 aminotransferases at **, because the improvement of autoimmunity hepatitis B antiviral ** is effective, and it is resistant to autoimmune clearance of the virus.

Before the beginning, in the case of autoimmunity and virus fighting, nucleoside drugs help the body control the virus, so autoimmunity prevails, and transaminases will increase slightly, but with the decline of the virus, transaminases will come down.

Therefore, during viral liver disease, the elevation of aminotransferases is not only related to drugs, but also related to other factors.

Do you understand?

Good luck soon**!