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The causes of thrombocytopenia can be divided into:
1) Decreased platelet production or ineffective death: including hereditary and acquired, acquired decreased platelet production is caused by certain factors such as drugs, malignant tumors, infections, ionizing radiation, etc. These factors can affect multiple hematopoietic cell systems, often with varying degrees of anemia, leukopenia, and markedly decreased megakaryocytes in the bone marrow.
2) Excessive platelet destruction: both congenital and acquired. Acquired platelet destruction overdestruction includes both immune and non-immune.
Immune platelet destruction is excessive, common are idiopathic thrombocytopenic purpura, and pharmacological thrombocytopenia. Nonimmune thrombocytopenia destroys too much including infection, disseminated intravascular coagulation, thrombotic thrombocytopenic purpura, etc.
3) Excessive retention of platelets in the spleen: most commonly in hypersplenism.
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The specifics of thrombocytopenia are unknown. Decreased platelet production or ineffective death can be inherited or acquired. Acquired thrombocytopenia is caused by certain factors such as drugs, malignant tumors, infections, ionizing radiation, etc., which damage the hematopoietic stem cell or affect its proliferation in the bone marrow.
The second is that too many platelets are retained in the spleen, and patients often have symptoms of hypersplenism. Finally, excessive platelet destruction, including congenital and acquired, acquired thrombocytopenia destruction is too high and includes immune and non-immune, immune platelet destruction is too much idiopathic thrombocytopenic purpura and drug thrombocytopenia, non-immune includes infection, diffuse intravascular coagulation, thrombotic thrombocytopenic purpura, etc.
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The root cause of this disease is caused by the defect of the body's immune mechanism, and the onset of the immune system is caused by the imbalance of the immune system, which is also known as immune thrombocytopenia in medicine.
There are many predisposing factors for this disease, including chemical poisons, radiation, ionizing radiation, injection vaccines, inflammatory virus infections, drugs, overwork, etc., these factors can only be speculated, and it is not certain what causes them. The important thing is how to cure the root cause and not repeat it, and if it is cured, it will not be affected by any factors and repeated.
The disease is the result, ** and the predisposing factors are not directly related, it needs to be combined with Chinese herbal medicine ** to achieve **, a good ** program is very important.
Dr. Gao.
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What is the platelet number? Have you had a bone marrow aspirate?
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The Department of Hematology of Ping'an Hospital Affiliated to Hebei Medical University is a national key clinical specialty of the Ministry of Health, with strong expert skills and rich clinical experience. If you need help from a hematologist or want to know more, you can consult with a hematologist for free** or call us at 400-0387-206.
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This kind of hospital is all Putian department, beware of becoming Wei Zexi.
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Beijing Western Medicine recommends Shang****, Peking University People's Hospital, Chinese medicine recommends Shangxiyuan Hospital, and the Affiliated Hospital of Life Medicine Engineering Institute.
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It is regarded as West China Hospital, and it has gone to Sichuan.
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Hello: Purpura ** and a general term for color change after mucosal hemorrhage. The clinical manifestations are hemorrhagic spots, purpura and ecchymosis, which are generally not high above the skin surface, and can only be slightly raised in the case of Henoch-Schonlein purpura, which is purple-red at first, and does not fade under pressure, and then gradually becomes lighter, and then turns yellow and fades in about two weeks.
Henoch-Schonlein purpura**.
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Hello, hormone use is difficult to repair for children, anyone***. And hormones can only relieve the patient's symptoms to some extent - they are not drugs to relieve the lesion.
It is recommended that you consult a professor of medical school or a professor-level chief physician of the hospital as soon as possible to solve the problem. If the effect is not good, it is recommended to take the child to Shanghai, or Beijing Children's Hospital, the Blood Disease Hospital of the Academy of Chinese Medicine, or the West China Hospital as soon as possible to try the re-treatment of traditional Chinese medicine**.
**: Primary thrombocytopenic purpura is an immune syndrome that is a common bleeding disorder. It is characterized by the presence of antiplatelet antibodies in the blood circulation, which destroys excessive platelets and causes purpura; In contrast, megakaryocytes in the bone marrow are normal or increased, and they are infantilized. Sun Ping.
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Thrombocytopenic purpura** has the following aspects.
1. Platelet-related antibodies.
Antiplatelet antibodies are present in serum in patients with chronic thrombocytopenic purpura. If the plasma of a patient with chronic thrombocytopenic purpura is transfused to a normal person, the normal person's thrombocytopenia can be reduced; If platelets from a normal person are transfused to an ITP patient, the transfused platelets are destroyed in a short period of time. This confirmed that the shortened platelet lifespan in ITP patients was due to the presence of platelet-destroying antibodies in the serum, called platelet-associated antibodies (PAIC3), 95% of which were IgG and a small number were IgM and IgM.
Platelet-associated complement C3 (PAC3) is present in the blood circulation in patients with ITP, and its increase is proportional to the increase in PAIG.
2. Mechanism of platelet destruction.
The average lifespan of normal platelets is 7 11 days, while the lifespan of platelets in patients with thrombocytopenic purpura is only 40 230 minutes. Because the spleen contains a large number of macrophages, it produces high concentrations of antiplatelet antibodies, and the slow flow of blood can block antibody-coated platelets, so the spleen is the main site of platelet destruction. The liver and bone marrow are also sites of platelet destruction.
Platelet destruction in chronic ITP is caused by antiplatelet antibodies that bind to their associated antigens and are engulfed by macrophages. Platelet destruction in acute thrombocytopenic purpura is one of the causes of platelet destruction due to the adsorption of viral antigens on the surface of platelets and binding to the corresponding antiviral antibodies.
3. Megakaryocyte maturation disorder.
Because platelets and megakaryocytes share a common antigen, antiplatelet antibodies can also inhibit bone marrow megakaryocytes, impairing them in maturation, thus affecting platelet production.
Fourth, other factors.
1. The role of estrogen: the chronic type is more common in women of childbearing age, and it is easy to do so during pregnancy, suggesting that estrogen may play a certain role in the pathogenesis of this disease, and it may be that estrogen can increase the ability of macrophages to phagocytosis and destruction of platelets;
2. Antibodies damage capillary endothelial cells, causing capillary permeability to increase and aggravate bleeding.
Hormones**, which have a greater impact on the child. You can learn about traditional Chinese medicine conditioning**. Early**.
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Hello, Western medicine ** program, hormones, C-globulin [immunoglobulin], immunosuppressants, transfusion of component platelets, spleen cutting, all over the country are the same, generally can play a certain role in alleviating the disease, but can not achieve the root cause, and the long-term use of hormones and immunosuppressants is very important to the body, with the reduction or discontinuation of the drug, platelets will still decline; C-ball can only be maintained for about a week to half a month, and some patients are only effective for a few days, and platelets will still decline when the drug is stopped; Multiple transfusions of component platelets are not recommended as they allow platelets to produce antibodies on their own, which accelerates the destruction of platelets.
It is recommended to combine Chinese herbal medicine, the amount of medicine for children is relatively small, frequent feeding within a day is acceptable, you need to go to a professional blood disease hospital to find a specialist to consult the condition, it is necessary to hurry up**. z
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It is caused by immunodeficiency, but also a common pediatric disease, the condition is serious, hormones are necessary--- based on the present, the hormone can be faded, do not be superstitious in private hospitals, hormone purpura is a very scientific approach, but also need to be checked later, purpura will cause splenomegaly and purpura nephritis, and so the child is older to pay attention to low salt and low fat, eat less legumes, meat needs to be controlled.
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What is the platelet number? Hormones *** big.
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**Thrombocytopenia, it is recommended that you choose traditional Chinese medicine, Chinese medicine pays attention to dialectical treatment, in terms of **, to clear heat and cool blood to stop bleeding, replenish qi and yin, promote blood circulation and eliminate stasis, and at the same time should participate in the liver and kidney, spleen and qi and other methods, in order to achieve both symptoms and root causes. And traditional Chinese medicine is relatively safe, and there is no problem of major or hormone damage. **Thrombocytopenic purpura, you can drink Chinese medicine to nourish the blood.
Spleen soup, the effect is still good. You can consult --i
O4 Eight This QQ, good luck.
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