What is an interleukin 1 receptor antagonist 20

Interleukins act on a variety of target cells such as T cells, B cells and natural killer cells, transmit immune messages through receptors on target cells, activate and regulate the growth, differentiation and maturation of blood cells, participate in the body's immune response, and participate in the pathological process of some diseases.

Interleukins are a class of cytokines produced by and acted on a variety of cells.

At present, at least 38 interleukins have been discovered, named IL-1 IL38, which are functionally complex, networked, and complexly overlapping. They play an important role in a series of processes such as the maturation, activation, proliferation and immunoregulation of immune cells, and they are also involved in a variety of physiological and pathological responses of the body.

The proliferation, differentiation, and function of immune system cells are regulated by a range of cytokines. According to the structural homology of cytokines, they can be divided into several protein families, such as IL-1 family, IL-6 family, IL-10 family, tumor necrosis factor family and hematopoietic factor family. Interleukins are interspersed among them.

Leukocyte acorn-cumber-mesophin acts on a variety of target cells such as T cells, B cells and natural killer cells, transmits immune information through receptors on target cells, activates and regulates the growth, differentiation and proliferation of blood cells, participates in the body's immune response, and participates in the pathological process of some diseases.

Interleukins are produced by the coarse cells of T microsphery, which can act on T cells, B cells, etc., and the main role is to enhance the killing power of T cells and promote the production of antibodies.

Interleukins: A class of cytokines secreted by white blood cells that regulate cell growth, differentiation, and immune activity. Interleukins play an important role in transmitting information, activating and regulating immune cells, mediating the activation, proliferation and differentiation of T and B cells, and in inflammatory responses.

Antitoxin: An antitoxin is an immunoglobulin (antibody) that neutralizes toxins.

Interferon: Interferon is a broad-spectrum antiviral agent, which is an active protein (mainly glycoprotein) produced by monocytes and lymphocytes, which does not directly kill or inhibit the virus, but mainly inhibits the cell production of antiviral proteins through the action of cell surface receptors, thereby inhibiting the replication of the virus; At the same time, it can also enhance the activity of natural killer cells, macrophages and T lymphocytes, thereby playing an immunomodulatory role and enhancing antiviral ability.

Interleukin-2, which is used to admonish** the lymphatic system, is used for 2-8 weeks per injection (in fact, 200,000 units) and 500,000 units every other day.

Adverse reactions] is the most common adverse reaction, fever, chills, dose-related, generally fever (around 38), can also have chills, high fever, body temperature more than 3 to 4 hours? , after stopping the drug, it returns to normal. Individual patients may present with nausea, vomiting, and flu-like symptoms.

Subcutaneous injection of local redness, swelling, induration, pain, and all *** can heal on their own after stopping the drug. When used in larger doses, this product may cause capillary leak syndrome, hypotension, peripheral edema, and transient renal insufficiency.

The FDA's safe dose should be strictly controlled, and the above reactions can be symptomatic**.

Contraindications] 1 case of allergic history. Ingredients of the product.

2 High fever, severe heart disease, hypotension, severe cardiac, renal insufficiency, abnormal lung function or organ transplant recipients.

History of recombinant human interleukin-2 medication, which has been associated with toxicity.

Precautions] (1) This product must be experienced. Interleukin-2, for the lymphatic system, is used in the lymphatic system, with a course of 2-8 weeks per injection (in fact, 200,000 units), and 500,000 units every other day.

Adverse reactions are the most common adverse reactions, fever, chills, dose-related, generally fever (around 38), but also chills, high fever, body temperature more than 3 to 4 hours? , after stopping the drug, it returns to normal. Individual patients may present with nausea, vomiting, and flu-like symptoms.

Subcutaneous injection of local redness, swelling, induration, pain, and all *** can heal on their own after stopping the drug. When used in larger doses, this product may cause capillary leak syndrome, hypotension, peripheral edema, and transient renal insufficiency.

The FDA's safe dose of socks should be strictly controlled, and the above reactions can be symptomatic**.

Contraindications] 1 case of allergic history. Ingredients of the product.

2 High fever, severe heart disease, hypotension, severe cardiac, renal insufficiency, abnormal lung function or organ transplant recipients.

History of recombinant human interleukin-2 medication, which has been associated with toxicity.

Precautions] (1) This product must be used with caution under the guidance of experienced experts.

2。The vial is cracked, damaged, and cannot be used. After the dissolution, the product is added to the transparent liquid of normal saline, such as turbidity, precipitation and other phenomena, which should not be used. Once you are done using the bottle open, do not use it more than once.

3。Excessive dosage can cause capillary leak syndrome, manifested as hypotension, angioedema, and patients with transient renal insufficiency should immediately discontinue use and immediately treat symptoms**.