Diabetics ask for help, and doctors ask them to take insulin

Insulin analogues are superior to human insulin in terms of efficacy and safety. The reason for the development of insulin analogues is to improve human insulin insufficiency. At present, insulin can only be injected subcutaneously, so its onset and duration of action do not match our physiological insulin secretion curve.

For short-acting human insulin, because it has a relatively slow onset of action, it does not coincide with our physiological insulin secretion in the early phase, so it leads to unsatisfactory postprandial blood sugar control in patients, and because of the long duration of action, it is easy to cause hypoglycemia before the next meal. In addition, due to the slow onset of action, patients need to be injected 30 minutes before meals, which is very inconvenient. Rapid-acting insulin analogues (such as insulin aspart) have a 50-year faster onset of action than short-acting human insulin, and the peak of the plasma insulin concentration curve is 50 higher, which better mimics our physiological early-phase insulin secretion curve, so postprandial blood glucose control is better, and preprandial hypoglycemia is less likely to occur due to the short duration of action.

Premixed insulin analogues (e.g., insulin aspart 30) are more suitable for use in Chinese patients with type 2 diabetes, and only need to be injected twice a day to control fasting and postprandial blood sugar, which is very convenient. In addition, achieving the same glycemic control requires 28 fewer doses than human insulin, so it costs about the same as human insulin. More importantly, insulin aspart 30 can delay the number of years of complications and prolong the survival of patients compared to human insulin.

Insulin analogues have been used for more than 10 years and have been verified by a large number of clinical studies to be very safe, and insulin aspart is also the only insulin analogue approved by the Food and Drug Administration of China for gestational diabetes, even pregnant women can use it, so it is very safe, and the landlord does not have to worry.

The analogue is good, but it is slightly more expensive.

Human insulin is cheap, and analogues are about 20-30 dollars more expensive.

The analogues are easy to use, and the side effects are about the same.

Because we are injected in vitro, the effect of the drug is slow, and the effect of the analogue is faster than that of human insulin, but it is not as fast as the secretion of our own pancreas.

It generally takes half an hour for insulin for ordinary people to take effect, which means that they must start eating half an hour after the injection.

And analogues, also known as fast-acting, do not need to eat, and you can eat right away after the fight. This is very convenient. Especially when you go out to eat, it is difficult to guarantee when you will be able to eat, so it is better to use fast acting.

Rapid-acting insulin is to replace a certain amino acid that does not affect the efficacy of human insulin with other amino acids, and its essence is still human insulin, nothing ***.

Insulin lowers blood sugar quickly, and there is no burden on pancreatic islets!

The deficiencies of human insulin are supplemented by insulin analogues.

Diabetics can make mistakes when injecting insulin multiple times, and this error is often made by patients who inject insulin multiple times a day.

Even some diabetics who have a lot of experience with injections can develop it.

Yesterday we talked about the timing error of long-acting insulin, which is the least dangerous behavior because long-acting insulin works for a longer time and has no peaks, which has the lowest chance of causing hypoglycemia.

The biggest concern for doctors is the wrong injection of rapid-acting or short-acting insulin.

Usually, in order to make it more convenient for patients to use, the injection time of long-acting insulin is chosen before bedtime, that is, between 9:00 and 11:00 p.m., and the family may be negligent in taking care of it during this time period and not finding the error in time.

In the morning, we often receive diabetic patients who are admitted to the emergency department, some of them are in a coma, and some of these patients are on insulin, so we do not rule out the possibility that the injection error is not detected in time, or it is found that it is not treated in time and correctly.

So how do you deal with injection errors that are discovered in time?

Both rapid-acting and short-acting insulin injections are food-related, i.e. they need to be eaten immediately after the injection or 30 minutes later.

You also need to eat after the wrong injection, and if your blood sugar is maintained well, the amount of food you eat is basically the same as your usual meal. If blood sugar control is poor, you can eat less, but you have to eat.

Hypoglycemia should be absolutely avoided during a long period of time when the duration of the night is long and the incidence of cardiovascular and cerebrovascular diseases is high.

It is best to check your blood sugar at 3 a.m. to determine your blood sugar at night, and treat it in time if you have low blood sugar.

I am Dr. Sun, who loves life and food, and I continue to provide you with high-quality health knowledge. Metabolic diseases such as diabetes and obesity are on the rise, and may also affect the well-being of families and the next generation. Good control of blood sugar and weight is the foundation of the best.

People with diabetes don't necessarily have to take insulin. Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, mainly caused by relative or absolute insufficiency of insulin secretion, or insulin resistance. Diabetes is divided into type 1 diabetes and type 2 diabetes.

In patients with type 1 diabetes, the islet cells cannot secrete insulin, resulting in an absolute shortage of insulin, so insulin must be administered**. Patients with type 2 diabetes mellitus are relatively deficient in insulin, some pancreatic islet cells can secrete insulin, and depending on the severity of the disease, some patients can take oral sulfonylureas and biguanides without insulin.

There are many types of diabetes, the most common being type 1 diabetes and type 2 diabetes. Patients with type 1 diabetes have an absolute lack of insulin in their bodies, and insulin must be used to lower blood sugar, so insulin must be effective for type 1 diabetes. The pathogenesis of type 2 diabetes can be summarized as two aspects: insulin resistance and relatively insufficient insulin secretion.

Patients with type 2 diabetes can also use insulin to lower blood sugar, but sometimes patients with type 2 diabetes have heavy insulin resistance, especially those with obesity type 2 diabetes patients with severe insulin resistance, which means that the body is not sensitive to the hypoglycemic effect of insulin, so it may be that a large dose of insulin is used and the blood sugar still does not drop ideally. This is not that insulin does not work, but that the effect of insulin cannot be exerted due to its own reasons, in this case, drugs that increase insulin sensitivity can be added, combined with insulin**, blood sugar can be lowered.

Although insulin is a biologic, it also has ***. There are many types of insulin, including hypoglycemia, weight gain, edema, eye refractive changes, induration at the injection site and lipoatrophy, among which hypoglycemia is the most common and the most important. When hypoglycemia occurs, patients may have symptoms such as dizziness, sweating, palpitation, hand tremors, hunger, and in severe cases, convulsions and coma.

If the patient develops these symptoms, blood glucose should be measured immediately with a blood glucose meter. If the test is less than 4 millimol liters, a small sweet tooth should be eaten immediately and blood glucose monitoring should continue until the blood glucose is maintained at a safe level. If rapid blood glucose measurement is not available, it can be treated as hypoglycemia.

For severe hypoglycemia, the patient should be sent to the nearest hospital immediately after simple treatment. According to practical observations, it was found that the injection of insulin is far from being the only one, according to a patient, a smart, veteran cadre who participated in the revolution in the early years said: "The result of insulin injection is that the more and more insulin, and finally there is no cure".

Yes, lobbying has seen less and less insulin. So the biggest *** is to fight more and more. Also, every day I get injections, I get eyes on my stomach, and some doctors say that there is no ***, which is the most obvious.

Moreover, from the perspective of balance, the balance of the human body every day depends on external forces to maintain, type 2 diabetic patients originally had the function of secreting pancreatic islets, but now how much dose is taken every day, the secretion function is no longer needed, and people have become robots, which eventually leads to the loss of pancreatic islet function and organ lesions.

Diabetic patients inject insulin or hypoglycemic drugs every day to avoid making blood sugar too high, but few people pay attention to it, and low blood sugar can also cause symptoms such as weakness and unconsciousness, and even coma is serious, and it is more likely to have accidents. Some patients take too much hypoglycemic drugs, or do not eat enough or delay eating and use hypoglycemic drugs or insulin, which may lead to hypoglycemic symptoms without realizing it! A 60-year-old diabetic woman went to the emergency department for dizziness and limb weakness during the Chinese New Year, and her blood sugar was only 45 mg dl.

The woman usually injects 50 units of insulin a day, but because she is busy preparing for the New Year, she often skips meals because she is busy preparing for the New Year, and she continues to inject 50 units of insulin every day, resulting in hypoglycemia symptoms. Ye Qichang, director of the Department of Secretinology and Metabolism of Taipei United Hospital Yangming Campus, said that after the woman's blood was injected with grape clear sugar solution supplementation, her symptoms had improved rapidly, and she first changed to 30 units of insulin per day, and then adjusted the insulin dose according to glycosylated hemoglobin. Ye Qichang pointed out that blood sugar less than 70 mg DL is called hypoglycemia, and the common causes of hypoglycemia are insufficient diet and continue to use hypoglycemic drugs or insulin, consume too many calories without proper supplementation, or delay in normal eating.

Urgent**Sugary drinks or candy biscuits can be consumed to relieve confusion that may be caused by hypoglycemia, and then supplement the main meal to avoid further hypoglycemia. Ye Qichang reminded that the symptoms of hypoglycemia are diverse, such as dizziness, cold sweat and hunger, and may also have blurred vision, difficulty speaking, abnormal behavior, unconsciousness or weakness of one limb (similar to stroke), and in severe cases, coma. Therefore, symptoms of hypoglycemia are prone to accidents, such as driving long distances or delaying eating due to traffic jams, and hypoglycemia can lead to car accidents.

Ye Qichang appealed that if they are engaged in activities such as mountain climbing, cycling, and long-distance driving, diabetics should bring their own candy and biscuits in case of emergency. Subscribe to the [Healthy Love Lohas] video and audio channel, read health knowledge more easily and clearly Join [], pay attention to your health every day! line＠ id：

Supply Article 8606 Diabetic patients who do not eat enough insulin Beware of hypoglycemia Keywords: insulin, hypoglycemia, diabetes, dizziness, chills, unconsciousness.

Diabetes is a serious threat to people's health, we should prevent it as soon as possible, but once you have diabetes, not everyone needs to take insulin, through the following introduction, you can simply understand, what kind of people need to take insulin, what kind of people don't need to take insulin! Which patients need insulin? (1) Type diabetes mellitus, regardless of the severity of the disease, with or without acute and chronic complications, requires lifelong insulin replacement**, and cannot be stopped abruptly, even during the "honeymoon phase".

(2) Type diabetes mellitus also requires insulin in the following situations**: (After reasonable diet, exercise and oral hypoglycemic drugs** Those who still do not meet the target of blood glucose control ( Those who fail to achieve oral hypoglycemic drugs ( Emaciated patients who are difficult to classify ( Concurrent acute metabolic disorders including ketoacidosis, non-ketotic hyperosmolar coma, lactic acidosis ( co-infection, wasting disease, severe liver and kidney disease, retinopathy, acute myocardial infarction, cerebrovascular accident and other stress states; or severe chronic complications ( Pregnancy Perioperative period of severe trauma during childbirth and large and medium-sized surgery ( Newly diagnosed Fasting blood glucose of type diabetes mellitus mmol l Hours after meals》 mmol l Glycosylated hemoglobin % Insulin boosting as soon as possible** to restore part of the islet function (3) Other types of diabetes mellitus such as pancreatic diabetes steroid diabetes Pituitary diabetes gestational diabetes, etc. Through the above analysis and description, you should have a general understanding of which patients need to use insulin. I hope the above description is helpful to everyone, and finally I wish you all a speedy recovery!