Why should diabetics supplement with vitamin B12?

Effects of vitamin B12 in diabetics

The researchers recommend that routine check-ups for diabetic patients taking metformin for a long time should include a vitamin B12 test.

Metformin is a commonly used drug for type 2 diabetes. For a long time, metformin has a definite curative effect, small and low cost. In the latest ** guidelines, metformin is designated as a first-line drug for type 2 diabetes.

However, any drug has its limitations. Although blood sugar control is good, according to the latest foreign research, patients who take metformin for a long time are prone to vitamin B12 deficiency, which can lead to fatigue, psychological changes, anemia and neurological disorders. Therefore, patients should have their vitamin B12 levels checked regularly.

The study was conducted by Cohen Stihaui and him from the VU University Medical Center in Amsterdam, the Netherlands. 390 people with type 2 diabetes were included in the study for more than 4 years. Participants took the pill three times a day, with 196 taking metformin and 194 taking a placebo.

Introduction to vitamin B12

Vitamin B12 is also known as cobalamin or cyanocobalamin. It is a vitamin B group composed of cobalt-containing porphyrin compounds. For the first time, it was discovered that taking whole liver could control the symptoms of pernicious anemia.

After 20 years of research, it was not until 1948 that a red crystalline substance with the effect of controlling pernicious anemia was isolated from the liver and named vitamin B12. Its structural formula was confirmed in 1963. The synthesis was completed in 1973.

Vitamin B12 is the most recent vitamin found in B vitamins to date. Vitamin B12 is a polycyclic compound containing trivalent cobalt. Four reduced pyrrole rings are linked together to form a large Goering ring (porphyrin-like), which is the core of the vitamin B12 molecule.

Therefore, compounds containing such rings are all referred to as Göring-like.

Because vitamin B12 promotes kidney development, it is excellent for diabetes.

Because vitamin B12 can help people with diabetes to keep their bodies stable.

This vitamin can effectively alleviate the development of diabetes, which will become more and more severe. So it needs to be added.

Because vitamin B12 supplementation can effectively alleviate the symptoms of diabetic patients.

If there is a lack of vitamin B12 in the diabetic body, the nervous system may be damaged, and the damage is irreversible.

This is because this vitamin is effective in relieving the symptoms of diabetes.

Because of the lack of vitamin B12, the disease will become more and more serious. So it needs to be added.

This is because diabetics lack this vitamin B12 in their bodies.

Vitamin C can provide a comfortable environment for diabetics, so that diabetes will be reduced.

Diabetics eat vitamin B12 because vitamin B12 nourishes the nerves. One of the complications of diabetes is called diabetic peripheral neuropathy, and patients usually have paresthesia and motor abnormalities in the distal limbs, such as hyperalgesia, numbness in the hands and feet, and some patients will also have symptoms such as cold extremities and decreased sensation. Vitamin B12, as a class of vitamin drugs that can nourish nerves, has a good effect on diabetic peripheral neuropathy.

Diabetics take vitamin B12 to replenish blood. Prevention and ** hyperhomocysteinemia and hyperhomocysteinemia are important risk factors for cardiovascular and cerebrovascular diseases, vitamin B12 can prevent diabetic hyperhomocysteinemia, prevent and ** neurological diseases, diabetic neuropathy is one of the most common chronic complications of diabetes. Vitamin deficiency is associated with the occurrence of diabetic neuropathy, and the use of vitamin B12 can prevent and ** diabetic neuropathy.

Many diabetic patients insist on taking hypoglycemic drugs to stabilize their condition, but they will feel unwell after eating for a period of time. Some patients may experience symptoms such as anemia, numbness and tingling in the limbs, and feel tired from time to time, do not want to eat, and are always tired. At this time, the doctor will advise them to take an additional medicine, vitamin B12, or prescribe methylcobalamin.

Such a drug adjustment makes some sugar friends feel incomprehensible. I take hypoglycemic drugs to stabilize blood sugar, so what is the purpose of taking vitamin B12 and methylcobalamin?

01Why do diabetics take vitamin B12 supplements?

In fact, the numbness and pinprick sensation in the limbs of sugar friends may be related to vitamin B12 deficiency. Not only that, vitamin B12 deficiency may also lead to megaloblastic anemia in the human body, which can lead to anorexia and cognitive impairment. Diabetic patients are at high risk of vitamin B12 deficiency.

This is mainly related to 3 factors.

First of all, sugar lovers need to strictly control their diet, which can lead to vitamin B12 deficiency in food**.

Vitamin B12 in nature mainly comes from microorganisms and is more common in meat and eggs. However, in order to avoid the rise in blood sugar, many sugar friends will deliberately reduce their meat intake. However, such a diet is likely to affect the way people supplement vitamin B12 through their diet.

Especially for some perennial sugar friends, this problem is more likely to occur.

This is because vitamin B12 can degrade blood sugar in diabetic patients and convert it into nutrients, so that blood sugar generally does not rise.

It is for better ** disease, in order to avoid physical problems, and to maintain good health.

This is done for the sake of good health, to avoid the condition becoming more serious, and to maintain the health of other organs of the body.

Because many sugar friends who use hypoglycemic drugs will have gastrointestinal tract***, especially metformin. Long-term use of metformin can lead to a decrease in the absorption of vitamin B12 in the intestines, causing its levels to decrease. The decrease in vitamin B12 levels is also associated with neuropathy, cardiovascular and cerebrovascular complications, anemia, and kidney disease in diabetic patients.

In addition, diabetics are more likely to suffer from nutritional imbalances due to dietary restrictions, which makes them more likely to be deficient in vitamin B12.

The specific ** mechanism is more complicatedAspects are related to age, mainly because vitamin B12 deficiency causes an increase in homocysteine, so it is inferred that vitamin B12 decreases with age; On the other handBecause many diabetic patients will take metformin hydrochloride for a long time to control blood sugar. For people with diabetes, long-term or high-dose oral administration increases the risk of reduced vitamin B12 levels.

What are the dangers of vitamin B12 deficiency? Vitamin B12 plays a role in the production of red blood cells, which carry oxygen in our body. Since oxygen is an important part of the body's energy production, anemia occurs when red blood cells are deficient, i.e., vitamin B12 deficiency.

Vitamin B12 is also an important part of a healthy nervous system, and a deficiency of vitamin B12 can cause slow degeneration of nerves in the brain, spinal cord, and peripheral nerves. When anemia is also presentWeakness and impaired neurological function associated with neuropathy are exacerbated.

Vitamin B12 deficiency can lead to memory loss, cognitive decline, behavioral changes, and self-care problems. If you have a severe and chronic vitamin B12 deficiency,Dementia may occur.

Take methylcobalamin, or methyl vitamin B12, to supplement vitamin B12 because vitamin B12 is a water-soluble vitamin, so even if you take too much, it will not be harmful to your body, because excess vitamin B12 is excreted in the urine.

Methylcobalaminis the most easily absorbed by the body, we can completely dissolve as long as we hold it under the tongue for 30 seconds, butBefore taking it, we should consult a doctor about the ideal and correct dosage.

Dietary supplements are the best dietary supplements, and the vitamin B12 in food is mainly found in animal offalFor example, pork liver, kidneys, etc., as well as animal meat and eggs. However, the high cholesterol content of animal viscera is not a suitable diet for diabetics. In addition, 30% of vitamin B12 is lost in cooking.

Therefore, it is necessary to supplement vitamin B12 with drugs.

ConclusionIf it is for vitamin B12 deficiency caused by metformin, as long as vitamin B12 is supplemented; If it is for neuropathy caused by diabetes, it is best to choose methylcobalamin. Vitamin B12 is best supplemented through diet and generally not excessive; If vitamin B12 is taken orally, it is important to follow your doctor's advice, and foods containing vitamin B12 should be reduced accordingly.

Studies have found that people with diabetes have a higher chance of developing vitamin B12 deficiency as they age. The reason for vitamin B12 deficiency in elderly diabetic patients is closely related to factors such as loss of appetite and weakened gastrointestinal absorption. The second is the impact of diabetes itself, insulin resistance, obesity and other factors on vitamin B12 absorption.

In obese and insulin resistant people, the incidence of vitamin B12 deficiency is often higher, and a statistical 10 17-year-old vitamin B12 test results of people with insulin resistance and obesity problems show that about 1 3 of obese adolescents with insulin resistance have vitamin B12 deficiency at the same time. The specific reason for the association between body mass index and vitamin B12 deficiency is not particularly clear, but it is initially thought that vitamin B12 is involved in the methylation process of DNA, while obese people have the problem of excessive methylation and consume more vitamin B12. Third, some long-term hypoglycemic drugs will also affect the absorption and utilization of vitamin B12 is an important vitamin needed by the human body, which has the effect of promoting methyl transfer, thereby promoting the development and maturation of red blood cells and maintaining the health of the nervous system.

Because the blood sugar in the body of diabetic patients is very high. Therefore, diabetic patients will be lacking, and they should be replenished regularly.

Diabetics have three more and one less symptoms, the metabolism is usually very fast, and they cannot absorb the nutrients of food well, so it will lead to the serious loss of these body fluids and the lack of vitamin B12. You can eat more leafy vegetables and fruits. It contains very high levels of vitamins.

You can also buy vitamin B12 for oral use.

Because of this disease, it will lose vitamin B12, so the body is generally relatively deficient in this element. Supplement with medication, or eat more vitamin-related foods on a daily basis.

Diabetes itself is not directly related to vitamin B12, and as long as diabetics can eat normally, the amount of vitamin B12 consumed from food is enough to meet the body's needs. Metformin is one of the most common hypoglycemic drugs for diabetes, it is reported that long-term use of metformin will affect the absorption of vitamin B12, and vitamin B12 deficiency will occur in severe cases, so if you take metformin for a long time to lower blood sugar, then under the premise of evidence, under the guidance of doctors, you can supplement vitamin eggs: eggs are a kind of nutrition that everyone is familiar with, its nutritional value is very high, rich in various minerals and trace elements required by the human body, and the content of vitamin B12 in eggs is very high, Therefore, in daily life, eating a little egg every day can supplement a large amount of vitamin B12 for the human body and promote the health of the human body.

2. Milk: Milk is also a food that people are very familiar with in life, and the content of various nutrients in milk is also very high. Drinking a glass of milk every day can meet the body's need for vitamin B12, so in life, we must pay attention to drinking more milk.

The physiological function of vitamin B12 determines that vitamin B12 deficiency can cause megaloblastic anemia, hyperhomocysteinemia, and neurological damage. For diabetic patients, the role of vitamin B12 is as follows: 1. Prevention and treatment of anemia, metformin is widely used in diabetes mellitus as a first-line drug for type 2 diabetes recommended by various guidelines.

Long-term use of metformin can cause vitamin B12 deficiency and cause megaloblastic anemia, and the application of vitamin B12 can prevent megaloblastic anemia. 2. Prevention and treatment of hyperhomocysteinemia, hyperhomocysteinemia is one of the important risk factors for the onset of cardiovascular and cerebrovascular diseases, and the application of vitamin B12 can prevent diabetes mellitus with hyperhomocysteinemia. 3. Prevention and treatment of nervous system lesions, diabetic neuropathy is one of the most common chronic complications of diabetes, vitamin deficiency is related to the occurrence of diabetic neuropathy, and the application of vitamin B12 can prevent and treat diabetic neuropathy.

Diabetes is a harmful disease, the biggest harm of diabetes is easy to cause complications, especially if the diabetic patients are not well controlled, it will also affect the occurrence of cardiovascular and cerebrovascular diseases, and in severe cases, the patient's body will be harmed.

1. Vitamin B12 is an indispensable trace element in the human body, mainly involved in the production of bone marrow red blood cells, preventing pernicious anemia, preventing brain nerves from being damaged, and used to maintain the health of the nervous system.

2. Most diabetic patients need to take drugs to control blood sugar, long-term use of hypoglycemic drugs will cause vitamin absorption disorders, which can easily lead to vitamin B12 deficiency in diabetic patients, and the lack of vitamin B12 in diabetic patients is easy to cause complications, which will have a serious impact on the health of patients.

Diabetes is a very harmful disease, patients want to better control the development of the disease, need to adjust their diet and improve their lives, but also take hypoglycemic drugs to control the rise of blood sugar and the occurrence of complications, in addition, diabetic patients should also properly supplement vitamin B12 to avoid vitamin B12 deficiency.