Is the onset of Parkinsonism related to exposure to metallic substances?

1. Familial hereditary: After a long-term follow-up investigation by some experts, it is found that Parkinson's disease seems to have a tendency to gather in families, and the incidence of Parkinson's disease patients in their relatives is higher than that of the normal population.

2. Environmental factors: After some statistics from experts, it has been found that there are certain regional differences in the incidence of Parkinson's, which makes people suspect that there may be some toxic substances in the environment that damage the neurons of the brain.

3. Genetic predisposition: Although the occurrence of Parkinson's disease is mainly related to the aging of the environment and age, not all elderly people or people exposed to the same environment, and even people who also smoke a large amount of MPTP will develop Parkinson's disease. Parkinson's disease is that although Parkinson's disease patients also have familial agglomeration, but so far there is no clear pathogenic gene found in sporadic Parkinson's disease patients, indicating that Parkinson's disease is multifactorial, and the current methods are mostly drugs, conventional Western medicine and special Longyuan Xi Trembling Soup.

It's still going to be timely.

Parkinson's disease is a middle-aged and elderly neurological disease, which is prone to cause a variety of complications after the lesion. At present, the incidence rate of Parkinson's disease in China is about the same, and it is estimated from the data that there are more than 2 million patients with Parkinson's disease in China, and at least 50% of the patients are delayed because they do not understand this kind of disease. What is Parkinson's disease?

1. What is Parkinson's disease?

Parkinson's disease, also known as parkinsonism, is caused by a lesion of the central nervous system and the death of a large number of neurons in the brain. It mainly occurs in the elderly, most of whom develop after the age of 60, and the incidence of Parkinson's disease is very low. A small number of patients suffer from Parkinson's disease because of family genetic factors, which has a certain hereditary nature and has a low chance.

2. What are the symptoms of Parkinson's.

1.Resting tremor: In the early stages of Parkinson's disease, 70 patients will be neurologically normal, and most patients will now experience tremors in the upper limbs, which will gradually worsen later depending on mood.

2.Muscle strength: Parkinson's patients will have a sense of resistance in the limbs in the later stage, the limbs will be stiff and weak in the early stage, and when the tremor is over, the force points of the limbs will be obstructed, which is the so-called muscle rigidity, but this kind of symptoms are not easy to detect in the early stage.

Second, what are the ** of Parkinson's.

1.Infection: Encephalitis infection is one of the main diseases of Parkinson's disease, encephalitis and other diseases have an incubation period, when the incubation period is over, it is easy to damage brain neurons after the outbreak, resulting in a significant increase in the mortality of brain nerve cells, thus causing Parkinson's disease.

2.Cerebral arteriosclerosis: The hardening of cerebral arteries will cause cerebral infarction in the brainstem, which will affect the dopamine pathway of black moles in the brain, and the pathway will be blocked and cause Parkinsonism.

Parkinson's disease is a type of parkinsonism syndrome. Parkinsonism may be a larger category, which refers to the occurrence of bradykinesia, tremors in the fluid limbs, stiffness of the limbs, or abnormal posture and gait. This large group of disorders is called parkinsonism.

Many Parkinson's disease patients or their family members often can't figure out the difference between Parkinson's syndrome and Parkinson's disease when they look up ** and prevention information on the Internet, thinking that they are the same disease. In fact, Parkinson's disease ≠ Parkinson's disease. Professor Wang of the Department of Neurosurgery of the hospital pointed out that the commonly known Parkinson's syndrome is not the same thing as primary Parkinson's disease.

1. Is Parkinson's syndrome the same as Parkinson's disease?

Parkinson's disease and parkinsonism, which may seem like a difference between a disease and a syndrome, are actually very different. From the perspective of pathogenesis, Parkinson's disease is the reduction of the dopamine neuronal chain in the substantia nigra of the midbrain, resulting in the deficiency of dopamine in the substantia nigra and striatum, while Parkinson's syndrome is caused by abnormal function of the extravertebral system of the motor regulation system caused by brain infection, trauma, hemorrhage, infarction, etc., so the syndrome is a group of symptoms (clinical manifestations) rather than a single disease.

2. What is the relationship between Parkinson's disease and Parkinson's syndrome?

Broadly speaking, Parkinson's disease is also a type of Parkinson's syndrome and is the most common type (about 80%), also known as "primary Parkinson's disease" or "idiopathic Parkinson's disease". What we are used to talking about is Parkinson's disease.

In a narrow sense, Parkinson's syndrome refers to a group of diseases with similar symptoms and signs of Parkinson's disease caused by various causes in addition to Parkinson's disease, which can be divided into secondary parkinsonism, parkinson's superposition syndrome and hereditary degenerative parkinsonism. In general, Parkinsonism progresses faster than Parkinson's disease.

Parkinson's disease is divided into the following four categories:

1. Parkinson's disease.

2. Secondary Parkinson's disease: Parkinson's disease caused by trauma, poisoning, drugs, cerebrovascular disease, tumor, encephalitis and other reasons.

3. Hereditary degenerative Parkinson's disease.

4. Parkinson's superposition syndrome.

When it comes to Parkinson's, many people are familiar with it. With the population base of **, the incidence of the elderly.

It also gradually increases. Parkinson's is one of the most common diseases in the elderly. Parkinson's disease will have a great impact on the human body, and often in the later stage, patients will have symptoms such as stiffness, inconvenience, inability to speak and communicate normally, and complete inability to take care of themselves.

In childbirth, we must improve the awareness and attention to Parkinson's.

Many people know about Parkinson's disease and Parkinsonism.

You may think that Parkinsonism is Parkinson's disease. Actually, there is a difference between Parkinsonism and Parkinson's. There is a difference between Parkinson's disease and Parkinson's syndrome, one is a large category and the other is a small category.

To use this analogy, the difference between the two is that Parkinson's disease is like a fruit, it's a big concept, and Parkinson's disease is a type of fruit, such as an apple. The metaphor of apples is due to the fact that in the field of fruits, apples are flat, neither cold nor hot, tepid, and very good, just like the manifestation of Parkinson's disease in Parkinson's syndrome, which can be said to be the slowest developing type with a better prognosis.

Parkinson's disease is easily misdiagnosed in the early stages, and tremor, stiffness, bradykinesia, and abnormal posture or gait are the four main symptoms of Parkinson's disease, in addition to some non-motor symptoms such as sleep disorders, psychiatric abnormalities, sensory disorders, and autonomic dysfunction. In daily life and work, if you or your family members are a little slow or sluggish, or even have the phenomenon of walking and dragging your steps, you need to make a diagnosis as soon as possible.

The onset of Parkinson's is related to genetic and environmental factors. Some scholars believe that insufficient intake of protein, fruits, dairy products, alcoholism, trauma, overwork and certain mental factors may be risk factors for disease. Paralysis tremens caused by an unexplained decrease in dopamine, medically called"Primary tremor paralysis", i.e., Parkinson's disease.

Parkinson's hair is known as: 1. Parkinson's hair has a certain relationship with aging. As the society gradually enters an aging society, Parkinson's disease mainly occurs with middle-aged and elderly people, and generally middle-aged and elderly people after the age of 40 are more likely to suffer from Parkinson's disease.

2. The emergence of environmental factors is also related to Parkinson's disease, in the epidemiological investigation, it was found that there are certain regional differences in the prevalence of Parkinson's, people in the northern region may be more diseased, Parkinson's may be related to toxic substances, damage to the neurons of the brain.

Parkinson's disease is a disease very similar to Parkinson's syndrome, age factors, emotional disorders, environmental factors and cerebral arteriosclerosis are common causes of Parkinson's disease.

Parkinson's disease is a degenerative disease of the nervous system in the middle-aged and elderly that we are all familiar with, such as tremor, postural balance disorders, bradykinesia, muscle rigidity and other motor symptoms, as well as abnormal sleep behavior and depression. Non-motor symptoms such as hyposmia and constipation are prominent clinical manifestations caused by Parkinson's disease. Since Parkinson's disease is a relatively serious chronic disease, it is difficult for patients to recover even after the relevant **, so we need to find the cause of Parkinson's disease and then do a good job in prevention.

The occurrence of Parkinson's disease is closely related to the following causes:

1. The existence of psychological and mental problems such as affective disorders is a very important reason for the formation of Parkinson's disease. People who are often plagued by various negative emotions such as anxiety, depression, and depression will have a higher record of being affected by Parkinson's disease, so you must pay attention to ensuring a happy mood and preventing depression during your later life, so as to reduce the incidence of Parkinson's disease.

2. The onset of Parkinson's disease and environmental factors are also related to a certain extent, and relevant investigation studies have shown that there are certain regional differences in the prevalence of Parkinson's neurological disease, so relevant researchers believe that some harmful substances in the environment may cause damage to neurons in the brain, leading to the production of Parkinson's disease.

3. Cerebral arteriosclerosis is an important factor that makes contemporary middle-aged and elderly people suffer from Parkinson's disease. The occurrence of cerebral arteriosclerosis, a disease of cerebral blood vessels, may affect the substantia nigra dopamine striatal pathway in the patient's brain, leading to the appearance of Parkinson's disease.

4. Age factor is one of the causes of Parkinson's disease, as we all know, middle-aged and elderly people are the main incidence of Parkinson's disease, but the increase of age is only a precipitating factor for the emergence of Parkinson's disease.

Continuous research has found that the cause of Parkinson's disease may be related to the following factors.

1. Aging: The elderly are generally susceptible to Parkinsonism. After middle age, individuals who are susceptible to environmental toxins, after being exposed to toxins, have subclinical damage to the substantia nigra due to their detoxification dysfunction, which worsens with age, and dopaminergic neurons gradually die and degenerate, and finally decompensate for the clinical symptoms of Parkinson's disease.

2. Environmental factors: There are some substances in the external environment, or chemicals similar to MPTP such as pesticides, which may cause Parkinson's disease.

3. Familial hereditary: Parkinson's disease seems to have a tendency to gather in families, and the incidence of Parkinson's disease patients in their relatives is higher than that of the normal population.

4. Genetic predisposition: Although the occurrence of Parkinson's disease is related to aging and environmental toxins, not all elderly people or people exposed to the same environment, even people who also smoke a large amount of MPTP will develop Parkinson's disease.

After long-term follow-up studies in the medical community, it has been found that no single factor can fully explain Parkinson's disease, and most researchers tend to believe that Parkinson's disease is the result of the combined effect of the above factors.

The hair of Parkinson's disease is related to the following:

First, genetic factors. In the late 90s of the 20th century, it was found that individual patients with familial Parkinson's disease in Italy, Greece and Germany had autosomal dominant inheritance, and its representative product was the main component of Lewy bodies. About 10% of patients are thought to have a family history, and the vast majority of patients are sporadic.

Second, environmental factors. A large number of studies on environmental factors have found that some pesticides, herbicides, rotenone, and isoquinolines in the environment may also be one of the most important compounds of Parkinson's disease.

Third, the aging of the nervous system. Some data show that after the age of 30, with age, the substantia nigra dopaminergic neurons begin to degenerate, and the dopaminergic neurons gradually decrease. However, it is not severe enough to cause the disease, and only a small number of people in the elderly population are affected, so neurological aging is only a contributing factor to Parkinson's disease.

Fourth, multi-factor interaction. At present, it is believed that Parkinson's disease is not caused by a single factor, but is caused by the interaction of multiple factors. In addition to gene mutations that cause the onset of disease in a small number of patients, gene susceptibility can increase the probability of disease, but it does not necessarily cause the disease, only under the combined action of environmental factors, nervous system aging and other factors, through oxidative stress, proteasome dysfunction, inflammatory immune response and other pathways.

1.The clinical presentation varies. Parkinson's disease is mainly manifested by slow movements, flustered gait, difficulty sitting up, involuntary hand tremor at rest, muscle stiffness, balance disorders, etc.

In addition to the similar manifestations of Parkinson's disease, Parkinson's disease may also have symptoms such as epilepsy, ataxia, eye movement disorders, hemiplegia, slurred speech, and dementia. And in terms of tremor, patients with Parkinson's disease usually have unilateral limb onset and resting tremor is the main body, while patients with Parkinson's syndrome have relatively less tremor and are usually postural tremor and action tremor.

2.The pathogenesis is different. Parkinson's disease is a primary disorder,** which is not well understood, while parkinsonism is a secondary disorder that includes secondary parkinsonism, parkinsonism superposition syndrome, and inherited degenerative parkinsonism.

Parkinsonism is known, that is, the pathological changes of the brain degenerate dopamine neurons, so that dopamine production is insufficient or can not transmit dopamine to maintain normal neurological function, and parkinsonism has a clear **, such as drugs, traumatic brain injury, poisoning, infection, etc.

3.Prognostic effects vary. Both Parkinson's and Parkinson's diseases can be relieved with medications. The difference is that Parkinson's disease is possible with medications, but Parkinson's disease cannot.

4.The age of onset varies. Parkinsonism can occur at any age, while Parkinson's disease usually begins in middle-aged and older adults.