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Digitalis drugs include: digitalis; digitalis toxins; Digoxin; Trichoside propylene is also known as cediran; Poison piloside K, also known as poison hair vortoside K.
Digitalis drugs are routine for heart failure, but they can sometimes cause or worsen heart failure. Therefore, follow-up examinations should be paid attention to during medication: blood pressure, heart rate and heart rhythm; Electrocardiogram; cardiac function monitoring; electrolytes, especially potassium, calcium, magnesium; renal function; When digitalis poisoning is suspected, the blood concentration of digoxin should be measured.
The pharmacological effects of rehmannia drugs are mainly positive inotropic and negative frequency, so they are often used for heart failure and atrial fibrillation.
Intravenous cediran can be used for acute heart failure, and oral maintenance dose of digoxin can be used for chronic heart failure. Intravenous cediran cardioversion can be given in rapid atrial fibrillation.
The precautions are: before injecting digitalis drugs, it is necessary to know whether the patient has used digitalis drugs within seven days, if so, the dose should be reduced intravenously, and if not, the conventional amount should be used. The amount of digitalis drugs is very close to the amount of poisoning, so during the medication, the patient should also pay close attention to whether there is new arrhythmia or blurred vision, digestive tract symptoms, etc., and blood can be drawn to test the blood concentration of digitalis if possible.
Observe whether there are symptoms of digitalis poisoning at any time, and reduce or stop the drug in time if there is any. Yes:
Gastrointestinal reactions: generally mild, nausea and vomiting are common. Diarrhoea, abdominal pain.
Cardiac response: sudden changes in heart rate are an important basis for diagnosing digitalis poisoning, and severe heart failure and atrioventricular block are common.
Neurological symptoms and visual disturbances: headache, dizziness, fatigue, insomnia, yellow or green vision may be present.
The pharmacological effects of rehmannia drugs are mainly positive inotropic and negative frequency, so they are often used for heart failure and atrial fibrillation.
Intravenous cediran can be used for acute heart failure, and oral maintenance dose of digoxin can be used for chronic heart failure. Intravenous cediran cardioversion can be given in rapid atrial fibrillation.
The precautions are: before injecting digitalis drugs, it is necessary to know whether the patient has used digitalis drugs within seven days, if so, the dose should be reduced intravenously, and if not, the conventional amount should be used. The amount of digitalis drugs is very close to the amount of poisoning, so during the medication, the patient should also pay close attention to whether there is new arrhythmia or blurred vision, digestive tract symptoms, etc., and blood can be drawn to test the blood concentration of digitalis if possible.
Observe whether there are symptoms of digitalis poisoning at any time, and reduce or stop the drug in time if there is any.
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The most famous is Digoxin.
It belongs to the cardiotonic drugs.
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Digitalis drugs are the most commonly used cardiac glycosides in clinical practice, which have the effect of positive inotropic and slowing down the heart rate, and do not increase myocardial oxygen consumption while increasing myocardial contractility.
1) Indications for digitalis drugs.
Congestive heart failure, particularly with atrial fibrillation and increased ventricular rate, is effective for supraventricular tachycardia, atrial fibrillation, and atrial flutter.
2) Contraindications to digitalis.
Acute myocardial infarction within 24 hours, severe atrioventricular block, hypertrophic obstructive cardiomyopathy. Digitalis poisoning or overdose is an absolute contraindication.
3) Toxic reaction of digitalis: its ** dose is close to the toxic dose, and poisoning is easy to occur.
The conditions that can easily lead to digitalis poisoning mainly include: renal insufficiency, hypokalemia, severe hypoxia, acute myocardial infarction, myocardial damage caused by acute myocarditis, old age, etc.
Common toxicities include:
Gastrointestinal reactions: decreased appetite, nausea, vomiting, etc.
Cardiovascular system reaction: It is a more serious toxic reaction of digitalis drugs, and various arrhythmias often occur, with ventricular premature contraction (also known as premature ventricular contractions, referred to as premature ventricular contractions) biad rhythm being the most common, as well as supraventricular tachycardia with atrioventricular block, sinus bradycardia, atrioventricular block, etc. Patients with long-term atrial fibrillation have a regular heart rhythm and fishhook-like changes in the ST segment of the ECG, and the risk of digitalis poisoning should be noted.
Nervous system reactions: headache, dizziness, blurred vision, yellow vision, green vision, etc.
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Answer]: B Digitalis contraindications: pre-excitation syndrome with atrial fibrillation, high-grade atrioventricular block, sick sinus syndrome; Hypertrophic cardiomyopathy, heart failure due to pericardial coarctation, acute myocardial infarction within 24 hours, cor pulmonale heart failure.
Hypertrophic cardiomyopathy is mainly manifested by ventricular diastolic dysfunction in the slag, and in the absence of systolic dysfunction, inotropic drugs (digitalis) are contraindicated. Please note that dilated cardiomyopathy is an indication for digitalis, but hypertrophic cardiomyopathy is a contraindication.
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