What is the function of panmoxicillin? What is the significance of his invention

The role of disinfection has been greatly contributed, saving millions of lives.

Before penicillin, severe wound infections and diseases such as pneumonia were almost 100 percent fatal. With this medicine, the mortality rate is almost zero.

Penicillin has saved millions of people and has made a big contribution.

One day in late July 1928, a mold spore of unknown origin fell to Fleming, a professor of bacteriology at St. Mary's School of Medicine, University of London.

Alexander Fleming, 1881 1955). At the time, Fleming was writing a retrospective of staphylococcus.

cultured in large numbers of Staphylococcus aureus (S. aureus aureus） 。But all of August.

Fleming was on vacation in the countryside and did not return to the lab until September 3.

Fleming returned from vacation and piled a pile of used petri dishes in the sink to prepare them.

Wash; A former assistant happened to be visiting, and Fleming picked up the top one and returned it.

A petri dish that has not been soaked in detergent should be shown to the assistant. Suddenly, his attention was strange.

Attraction of the peculiar landscape: The petri dish overgrown with bacteria has a patch of mold growing in the corner.

Bacteria, but the surroundings are clean and slippery, and bacteria do not grow. Fleming immediately thought of the mold.

It secretes a substance that kills bacteria or inhibits their growth. So Fry.

Ming took out the mold from the petri dish and cultured it, and tried to isolate the effective ingredients from it.

Divide; Penicillin (also known as penicillin) was born.

In fact, as early as 1921, Fleming had experienced a similar discovery. While.

When he took the nasal water that came out of his cold as a culture, he found that there was some kind of naturalness in it.

, resulting in a clear, sterile area on the Petri dish. Follow-up studies.

Found in various bodily fluids such as tears, saliva, sputum, plasma, as well as egg whites, fish.

This substance is present in the eggs. Because this substance has protein enzymes.

Penicillin 2 properties, Fleming's boss Almroth Wright named it Lytic.

Significance: Penicillin saved most of the Allied soldiers during World War II from the death caused by war, and penicillin is a revolution in medical technology, representing the development of medicine, which means that medicine has taken a more scientific step.

Before penicillin, severe wound infections and other diseases were almost 100% fatal. With this medicine, the mortality rate is reduced to zero.

Penicillin is a type of antibiotic, which is a drug extracted from the culture of Penicillium and is the first antibiotic capable of human diseases. The discoverer of mycin was the British bacteriologist Fleming. One day in 1928, Fleming was studying staphylococcus bacteria, which cause fever in the human body, in one of his modest laboratories.

Since the lid was not properly closed, he noticed that the agar used to grow the bacteria had a layer of Penicillium attached to it. This was from the window of a scholar who studied penicillium upstairs. To Fleming's surprise, in the immediate vicinity of Penicillium, the staphylococci suddenly disappeared.

Fascinated by this serendipitous discovery, he managed to grow the mold in several experiments that proved that penicillin could kill all staphylococci in a matter of hours. Fleming thus invented penicillin, the nemesis of staphylococcus. Penicillin inventor, British scientist Fleming, in the laboratory of Australian pathologist Howard.

In 1929, Fleming published an academic report on his findings, but it was not taken seriously at the time, and the problem of penicillin purification had not yet been solved. In 1935, Philip Lee, a biochemist at the University of Oxford, and Flory, a physicist, became interested in Fleming's discovery. Chin was responsible for the cultivation of Penicillium and the isolation, purification and strengthening of penicillin, which increased its antibacterial power by thousands of times, and Florey was responsible for observing and testing animals.

So far, the efficacy of penicillin has been demonstrated. Due to the discovery and mass production of penicillin, the lives of millions of patients with pneumonia, meningitis, abscess, and sepsis were saved, and many wounded and sick people were rescued in time. The advent of penicillin caused a sensation in the world at that time.

In recognition of this contribution to the benefit of mankind, Fleming, Chann and Florey jointly won the Nobel Prize in Medicine and Physiology in 1945. In 1943, there were enough penicillin** wounded soldiers; In 1950, production was sufficient to meet the needs of the whole world. The discovery and research of penicillin became a miracle in the history of medicine.

Penicillin has been used in clinical practice for three generations.

Penicillin is penicillin.

Amoxicillin is Penicillium hydroxycanicillin.

is also a penicillin.

Efficacy of penicillin.

It has a bactericidal effect during the bacterial reproduction period, and has strong antibacterial effect on gram-positive cocci (streptococcus, pneumococcus, susceptible staphylococci) and gram-negative cocci (meningococci, gonorrhoea), and has antibacterial effect on gram-positive bacilli (diphtheria), spirochetes (treponema pallidum, relapsing spirochetes, leptospira), clostridium (tetanus bacillus, gas gangrene), actinomycetes and some bacteroides.