What are the causes of gradual muscle atrophy?

There are many associations of muscle atrophy and can be caused by a variety of underlying disorders and trauma.

Essential**. Genetic factors.

For example, Duchenne muscular dystrophy, also known as pseudohypertrophic muscular dystrophy, is a genetic disorder. Patients with this type of disease develop in adolescence and have difficulty rolling over, sitting up, and standing up. The disease is rare, there is no way to do it, and muscle atrophy will gradually worsen until death.

Neuropathy. It mainly refers to neurogenic amyotrophic atrophy, such as amyotrophic lateral sclerosis, cerebral infarction, poliomyelitis, etc. Nerve lesions can cause nerve signaling disorders, which can lead to the disuse of some muscle fibers, reduced exercise capacity, and disuse muscle atrophy.

In addition, when neurons are damaged, the release of acetylcholine from their terminals decreases, and neurotrophic effects are weakened, resulting in muscle atrophy.

Trauma. When a fracture occurs, it may cause muscle atrophy in the affected area. On the one hand, during the fracture**, due to the long-term fixation of the affected limb and other reasons, the limb activity is reduced, and disuse muscle atrophy occurs.

On the other hand, a fracture may damage the surrounding nerves or cause compression of the spinal cord or nerves, and muscle atrophy may occur in the innervated area.

Other diseases. For example, cervical spondylosis, lumbar disc herniation, tumors, etc. can cause compression of the spinal cord and nerves in the corresponding parts, which may cause muscle atrophy;

Anorexia, malnutrition, Cushing's syndrome, hyperthyroidism, etc. can also cause muscle atrophy;

Inflammatory diseases, such as myositis, arthritis, and chronic infection can also cause muscle atrophy.

Predisposing factors. Certain lifestyle habits such as sitting for long periods of time and lack of muscle exercise can increase the risk of muscle wasting. Some long-term strenuous exercise, such as marathon, will cause muscle cell damage and death due to overuse of muscle cells, and eventually cause muscle atrophy.

The main reason for this is the degeneration of neurons, because I am also innervated through the nerves.

There are many reasons for the gradual atrophy of muscles, first of all, pathological reasons, pathological reasons make some people unable to fully move and mobilize the muscles of some parts of her body, so this part of the muscles, it will gradually atrophy, and some of them are due to their bad habits for a long time, sitting or fighting for a long time, and have been maintaining a certain posture, fixed like this for a long time, and if they do not exercise, the muscles will also atrophy, and there will be such a situation. We should do a reasonable exercise to improve such a situation and avoid an unreasonable atrophy of our muscles.

The cause of muscle atrophy is disuse muscular atrophy, such as stroke will lead to limited function of the limbs, and in severe cases, there will be a significant decrease in muscle strength. For example, the muscle strength of the zero level will cause obvious paralysis, and long-term existence will lead to muscle atrophy. Paraplegia patients are more likely to experience muscle atrophy, and some muscle injuries and fractures may lead to muscle atrophy.

There is also a disease of progressive amyotrophy, the patient's condition is still relatively critical, which will affect the muscles of the entire human body to produce muscle atrophy, and even affect the patient's life. This disease is also noteworthy and a serious cause of muscle wasting. It should be aimed at the ** of amyotrophy, as well as with traditional Chinese medicine, acupuncture, massage, etc., to promote muscle recovery and ** training.

There are many causes of muscle atrophy, such as systemic dystrophic atrophy, disuse atrophy, endocrine abnormalities, neurogenic atrophy, muscle-derived atrophy and muscle atrophy caused by other reasons, such as muscle atrophy caused by systemic diseases, hematologic diseases, endocrine diseases, osteoarthritis, fractures and other diseases. Common neurogenic muscle atrophy is the loss of neuronal cells, especially motor neurons, and the loss of innervation of local muscle tissue, resulting in muscle weakness, numbness, and atrophy.

There are many causes of muscle atrophy, the most common of which is disuse atrophy, which is caused by prolonged use. For example, after fracture and trauma, muscle atrophy can be caused by long-term immobilization and restriction of activities, which is called disuse atrophy. This muscle atrophy can be fully recovered at a later stage with active exercise, and there is no need to worry.

Upper neuron damage, muscle and soft tissue damage, electrolyte imbalances, medications, and long-term disuse can all be caused.

**1.Neurogenic amyotrophy.

1) Neurological lesions: such as cerebral infarction, polio, etc., causing nerve signaling disorders and reduced neurotrophic effects, resulting in muscle atrophy.

2) Orthopedic diseases: such as cervical spondylosis, lumbar disc herniation, etc., compression of nerves will cause muscle atrophy.

3) Trauma: such as fractures, limbs that cannot move normally for a long time may damage peripheral nerves, causing muscle atrophy.

2.Myogenic amyotrophy.

1) Muscle diseases: such as muscular dystrophy, is a common cause of myogenic amyotrophy.

2) Genetic factors: such as the rare Duchenne muscular dystrophy, is a type of genetic disease.

Factors that increase the disease.

Muscle wasting can be caused by poor nutrition, prolonged inactivity, or prolonged strenuous exercise.

High-risk populations.

1.Manual laborers: This type of person is mainly caused by excessive physical activity and excessive use of muscles.

2.Middle-aged and elderly people: mainly because of too little exercise, and even some people who have been bedridden for a long time, will have disuse muscle atrophy.

Nerve damage, decreased or loss of motor function, nutritional deficiencies, inability to provide adequate energy, etc.

There are several causes of muscle atrophy, first of all, it is caused by muscle diseases, myositis such as polymyositis, and patients will have muscle atrophy and muscle damage. Secondly, patients with myasthenia gravis, there is a type of myasthenia gravis that is amyotrophic type, and patients can also develop muscle atrophy. There are also diseases of the peripheral nerves, such as diabetes, and the situation caused by metabolic factors after poisoning, or autoimmune factors, resulting in more serious muscle atrophy, which is caused by neurological factors caused by peripheral neuropathy.

Central nervous systems, such as spinal cord lesions, can also cause muscle wasting.

1. Nerve damage leads to atrophy. For example, in lumbar disc herniation, nerve roots are compressed for a long time, and neuralgia occurs in muscle groups; For example, muscle atrophy occurs in the hips and legs, and neuralgia occurs when muscle atrophy. 2. Disuse degeneration leads to atrophy.

If the patient is old and needs to stay in bed for a long time, the muscles will be inactive for a long time, which is disuse degeneration, resulting in muscle atrophy.

Neurogenic amyotrophy.

Common causes are disuse, nutritional disorders, ischemia, and poisoning. Anterior horn lesions, nerve roots, plexus, peripheral nerve lesions, etc. can cause conduction disorders of nerve excitatory impulses, so that some muscle fibers are disused, resulting in disuse amyotrophy. On the other hand, after any part of the motor neuron is damaged, the release of acetylcholine from its terminal part decreases, and the sympathetic nerve nutrition is weakened, resulting in muscle atrophy.

2.Myogenic amyotrophy.

Spinal muscular muscular atrophy is confirmed by morphological examination in patients with muscular dystrophy caused by muscle disease and possibly other factors, such as shoulder girdle or facescapulohumeral pattern. Examination of animals with muscular dystrophy using microelectrode techniques shows that functional denervation of myofibers accounts for about 1 3.

There are two main groups of factors that can cause "amyotrophy": nerve damage is called neurogenic amyotrophy; The disease of the muscles themselves is called myogenic amyotrophy.

There are generally several causes of muscle atrophy:

1. Spinal cord lesions, such as spinal cord compression, injury, herpes zoster myelitis, birth trauma and acute anterior spinal cord polio, etc. These causes of muscle atrophy are common.

2. Neuronal amyotrophy complicated by diffuse lesions of the central nervous system, such as chronic progressive chorea, motor n-element disease, spongy autoplasmic encephalopathy, cerebral lobar atrophy, etc. This is also what causes muscle atrophy.

3. Secondary central nervous system muscle atrophy caused by congenital developmental malformations, such as cerebromyelocele, congenital cranial nerve nucleus hypoplasia, spinal cord development, hydromyelosis, syringomyelia, syringomyelia, etc. This is also a cause of muscle wasting.