What are the clinical manifestations of amyotrophy?

Muscle atrophy can cause weakness in walking, inability to stand, inability to squat, inability to step, etc., and muscle weakness in the hand can cause abnormalities in some hand movements, such as not being able to clench fists, not being able to do some fine movements, etc., and at the same time there is significant weight loss. It can also lead to some accompanying symptoms due to common causes, such as neurogenic muscle atrophy, in addition to muscle atrophy in the corresponding innervated area, there will also be paresthesias, such as decreased sensation, weakness, ant crawling sensation, etc

Muscular atrophy mainly refers to a series of clinical diseases such as the reduction of the volume or volume of the corresponding muscles caused by various reasons, which causes a series of clinical diseases such as muscle strength loss, which actually causes muscle atrophy. For the common clinical manifestations of muscle atrophy, the main is that the atrophied muscles appear smaller in volume or volume, and produce some deformities of the limbs, if the muscles of the limbs are atrophied, the limbs will be thinner, the deltoid muscle atrophy will appear obvious square shoulder deformity, the normal roundness of the shoulder joint will disappear, the atrophy of the hand muscles will appear flattened of the hand, and if the atrophied muscles are more obvious, the corresponding muscle strength will also decrease.

Muscle atrophy of the lower limbs can cause weakness in walking, inability to stand, inability to squat, inability to step, etc., and muscle weakness in the hand can cause abnormalities in some movements of the hand, such as inability to make fists, inability to do some fine movements, etc., and significant weight loss. It will also lead to some accompanying symptoms due to common reasons, such as muscle atrophy caused by neurogenic disease, in addition to muscle atrophy in the corresponding innervation area, there will also be paresthesia, such as decreased sensation and weakness, ant crawling sensation, etc., if it is myogenic muscle atrophy, there can be local muscle pain and soreness, muscle atrophy is often a more serious disease manifestation, should be checked and diagnosed in the hospital as soon as possible.

Atrophy includes: thigh muscle atrophy, calf muscle atrophy, shoulder girdle muscle atrophy, facial muscle atrophy, interosseous muscle and thenar muscle atrophy, etc.

In the early stage of muscle atrophy, there will generally be weakness and weakness of the lower limbs, inability to stand for a long time, and soreness and weakness of the lumbar spine. Sensory disturbance or loss of pain in one or both sides. It is accompanied by dizziness, tinnitus, enuresis, little red tongue and thin pulses.

In life, we must understand the symptoms of muscle atrophy, so that it can be detected and advanced in time at the early stage of the disease to prevent further aggravation of the disease.

1.Neurogenic amyotrophia: due to lower motor neurons and their damage.

When the anterior horn cells and brainstem motor nerve nuclei are damaged, the muscle atrophy is segmental, mostly distal to the limbs, symmetrical or asymmetrical, without sensory impairment, fasciculations often occur, and the degree of muscle strength and tendon reflexes is related to the degree of damage. Electromyography shows myofiber tremor potentials or high-amplitude motor unit potentials. Biopsy shows muscle atrophy and thinning.

Microscopic fascicular atrophy changes.

2.Myogenic atrophy: caused by a disease of the muscles themselves.

Atrophy is not distributed according to the nerve, usually proximal pelvic girdle and shoulder girdle symmetrical muscle atrophy, and rarely distal. With muscle weakness, no muscle fibrillation, and sensory deficits. Serum creatine phosphokinase, lactate dehydrogenase, aspartate aminotransferase, phosphoglucose mutase, and aldolase were all increased to varying degrees, and muscle weight phosphokinase was the most sensitive.

Electromyography is characterised by the presence of short-term multiphasic potentials.

3.Other: central amyotrophy is usually accompanied by hyperreflexia or pathological reflexes. Ischemic amyotrophy is mostly caused by various arteritis, thrombosis and other muscle ischemia and aseptic necrosis. Disuse amyotrophy is associated with long-term inactivity and is mostly reversible.