What causes cerebellar atrophy? What causes cerebellar atrophy?

There are many causes of cerebellar atrophy, which can be seen in the following conditions: 1. Hereditary, which can be seen in hereditary cerebellar ataxia, olive bridge cerebellar atrophy and other diseases. 2. Long-term insufficiency of blood supply to the brain, such as chronic ischemia and hypoxia of the cerebellum caused by cerebral atherosclerosis, and gradual cerebellar atrophy.

3. Poisoning can be a drug for diseases, such as phenytoin for epilepsy, or it can be caused by long-term drinking to cause cerebellar cell poisoning damage and then atrophy. 4. Cerebrovascular disease, cerebellar hemorrhage or infarction, when hematoma or infarct focus is absorbed, it is gradually replaced by collagen fibers and causes cerebellar atrophy. 5. Infection, pathogenic microorganisms invade the brain and affect the cerebellum, which can also cause atrophy and changes in the later stage.

6. Congenital developmental disorders, women are affected by some external factors such as benzene, heavy metals, air pollution, viral infections, etc., which can affect brain development during pregnancy, which can lead to cerebellar atrophy.

1. Endocrine diseases: It is a common cerebellar atrophy, such as diabetes, hyperlipidemia, hypothyroidism and hypoparathyroidism may cause cerebellar atrophy.

3. Cerebrovascular disease: It is related to cerebral infarction, cerebral thrombosis, cerebral hemorrhage and other diseases, due to a series of factors such as increased blood viscosity, slower blood flow, and rough blood vessel wall, which cause wall thrombosis. The narrowing or even blockage of the lumen of the blood vessels leads to ischemia, hypoxia, atrophy and even necrosis of the brain tissue cells in the vascular distribution area, and finally the cerebellar atrophy and death.

This is the most common type of cerebellar atrophy.

4. Tumor: Metabolic disorders caused by malignant tumors can lead to cerebellar atrophy, which is also a common type of cerebellar atrophy. Brain tumors can also directly damage brain tissue, leading to cerebellar atrophy.

The causes of cerebellar atrophy include physiological and pathological causes.

The physiological reason is that with the aging of the body, brain cells will generally shrink, which in turn leads to a decrease in the number of brain cells, a decrease in brain volume, and the phenomenon of cerebellar atrophy. This is a normal physiological phenomenon that cannot be alleviated.

Pathological causes include hereditary ataxia, drug intoxication, inflammatory diseases, paraneoplastic syndromes, etc. Hereditary ataxia is caused by poor limb balance, unsteady gait, inability to walk, need to rely on a wheelchair, and cerebellar atrophy. For patients with carbon monoxide poisoning, phenytoin and other drug poisoning, cerebellar atrophy can occur.

In patients with acute cerebellar hailitis, cerebellar atrophy occurs as sequelae.

Patients with cerebellar atrophy are currently not specific** and require symptomatic management of complications.

Cerebellar atrophy can be mainly divided into congenital and acquired: congenital is mainly common in adolescent patients, mainly related to genetic inheritance, and the representative disease is spinocerebellar ataxia, which is manifested as a series of fibrous manifestations of unsteady walking, limb atrophy, muscle weakness and laughter in adolescent patients.

There are more acquired **, mainly including some cerebrovascular diseases, encephalitis, brain trauma and poisoning, etc., especially some patients who take drugs can have cerebellar atrophy, cerebellar ataxia and a series of damage manifestations.

There are many causes of cerebellar atrophy, and the main reasons are as follows:

1. Genetic funny factors: hereditary spinocerebellar ataxia, due to genetic variation, the common hereditary verterebellar ataxia pathogenic gene in China is the pathogenic gene Wang Yuan of the SCA3 subtype;

2. Alcoholism: Long-term alcoholism can cause alcoholic cerebellar degeneration, leading to nutritional metabolism disorders and cerebellar atrophy;

3. Cerebrovascular accident: it will cause cerebellar hemorrhage or infarction, and local cerebellar atrophy will occur after **;

4. Head disease: In addition, tumors and trauma of the head can also cause local atrophy of the cerebellum.

In clinical practice, many causes can cause atrophy of the abrupt atrophy of the aconolith.

First, degeneration. With the growth of age, the human body will have different degrees of degeneration, cerebellum will also appear degenerative lesions, many people in the head CT or MRI examination, will indicate cerebellar atrophy, and the vast majority of mild cerebellar atrophy patients will be accompanied by obvious symptoms, more serious patients will have ataxia, percussion and voluntary movement disorders.

Second, organic lesions.

Cerebellar atrophy can be caused by many causes, such as trauma at birth as a child, which can cause cerebellar atrophy. Hereditary factors, such as hereditary ataxia, manifest as spinocerebellar atrophy. In addition, when we get older, degenerative diseases appear, which are manifested as cerebellar atrophy, brainstem atrophy, ataxia, dysphagia, choking on water, etc.

There are also some factors such as cerebral ischemia and hypoxia, which cause large arteriosclerosis, and cerebellar atrophy caused by high blood pressure, diabetes and other factors. Inflammatory factors, such as cerebellar inflammation and autoimmune inflammation, can cause cerebellar atrophy and cerebellar symptoms. There are also cases where cerebellar atrophy is associated with trauma, which can also lead to cerebellar atrophy.

What are the causes of cerebellar atrophy?

Hereditary diseases: spinocerebellar degeneration (SCA), Friedreich ataxia, dentate erythrocy, globus pallidus, Lewy body atrophy, etc.

Degenerative diseases: multiple system atrophy cerebral type (MSA-C), etc.

Ischemic-hypoxic diseases: such as acute cerebral infarction, cerebral hemorrhage, carbon monoxide poisoning, etc.

Drug poisoning: such as phenytoin, etc.

Inflammatory diseases: sequelae of acute cerebellia.

Alcoholism: alcoholic cerebellar degeneration.

Other: Neurological paraneoplastic syndrome.

Cerebellar atrophy has both physiological and pathological causes. The physiological reason is mainly due to the increase of age in the body, the apoptosis of brain cells generally, which leads to a decrease in the number of brain cells, a decrease in the volume of the brain, a decrease in brain weight, and the symptoms of global brain atrophy, and the cerebellum can not avoid atrophy, which is a normal physiological phenomenon and is not necessary. There are also patients with pathological phenomena, such as hereditary ataxia, when the patient's cerebellar atrophy will be obvious, the age of onset can be 20-30 years old or 50 years old, the patient shows poor limb balance, unstable gait, and some patients can not walk and need to do a wheelchair.

In addition, carbon monoxide poisoning can also cause cerebellar atrophy; Traumatic cerebellar atrophy is also common; Drug poisoning can also cause cerebellar atrophy.

There are many causes of cerebellar atrophy, and cerebellar atrophy diseases cannot be completely controlled.

For example, cerebellar atrophy caused by cerebral ischemia, then this situation should be targeted to improve the problem of cerebral ischemia to prevent cerebellar atrophy from continuing to worsen.

If cerebellar atrophy is caused by the lack of trace elements in the body, such as lack of folic acid or vitamin B12, then it is necessary to supplement folic acid or vitamin B12 to prevent the further aggravation of cerebellar atrophy.

During this period, patients should also have appropriate physical exercise in their daily life, avoid overwork, avoid emotional tension and excessive pressure, which can effectively prevent the further aggravation of cerebellar atrophy.

1.Cerebral infarction: whether ischemic or hemorrhagic cerebral infarction, it can occur in the later stage, and patients with severe cerebral atrophy can form softening foci.

Although the number of people with multiple lacunar cerebral infarctions that progress to cerebral atrophy is small, most patients with cerebral atrophy can lead to dementia. Therefore, it is one of the causes of cerebellar atrophy.

2.Cerebellar atrophy of the cerebral hemispheres: due to massive cerebral infarction or hypoplasia due to vascular occlusion in the fetal or neonatal period. It is also an important factor in the common causes of cerebellar atrophy.

3.Cerebral calcification: patients with cerebellar atrophy often have concomitant leakage with ipsilateral vascular nevi. Diffuse calcified regression zones throughout the brain can lead to cerebral atrophy, dementia, or mental retardation.

4.After bacterial and viral infection: cerebellar atrophy is mostly secondary to meningitis, encephalitis, brain abscess and other sequelae.

Cerebellar atrophy The atrophy of the brain**, using the nerve repair system, the precise atrophy of encephalopathy, breaking through the tradition, to achieve the special treatment of infiltration plexus disease, so that the atrophy patients with brain sleepiness and screaming can recover movement disorders, stupidity, and poor memory.

There are many causes of cerebellar atrophy, and the main reasons are as follows:

1. Genetic factors: hereditary spinocerebellar ataxia, due to genetic mutation, the common hereditary verteocrebellar ataxia pathogenic gene in China is the pathogenic gene of the SCA3 subtype;

2. Alcoholism: Long-term alcoholism can cause alcoholic cerebellar degeneration, leading to nutritional metabolism disorders and cerebellar atrophy;

3. Cerebrovascular accident: it will cause cerebellar hemorrhage or infarction, and local cerebellar atrophy will occur after **;

4. Head disease: In addition, tumors and trauma of the head may also cause local atrophy of the cerebellum.

The causes of cerebellar atrophy may be related to hereditary or degenerative diseases, or it may be caused by certain acute processes, such as the later stages of acute cerebellitis and drug poisoning. The basic causes include hereditary diseases, such as spinocerebellar degeneration, degenerative diseases such as multiple system atrophy and cerebral type, and ischemic diseases such as acute cerebral infarction, cerebral hemorrhage, carbon monoxide poisoning, etc.

For pharmacological reasons, such as phenytoin and other drugs can cause clinical manifestations of cerebellar atrophy, inflammatory diseases include the sequelae of acute cerebellia, alcoholic cerebellar degeneration can be caused by alcoholism, and other neurological paraneoplastic syndromes can cause cerebellar atrophy.

Brain atrophy itself is a big concept, and in clinical work, there will be many patients who will run over, and occasionally find brain atrophy in the process of doing examinations or CT or MRI. If there is cerebellar atrophy, it is also important to note that the brain structure does shrink slightly as you grow older than when you were young, but general atrophy is a uniform atrophy of the brain and cerebellum. If, during the examination, only cerebellar atrophy is found, but no significant atrophy is found in the brain or elsewhere, it should be taken seriously.

Because cerebellar atrophy alone is the case, ataxia is often possible. The function of the cerebellum is to maintain balance, assuming that after cerebellar atrophy, it will cause ataxia, which means that in the process of walking, like drunk, walking will be shaky, unsteady walking, and the calves will be very open when walking in order to maintain balance. In addition to cerebellar ataxia, some patients may be inherited, and some patients will have multiple system atrophy, which may be manifested by cerebellar or brainstem atrophy.

Cerebellar atrophy is a manifestation of the disease that causes ataxia (unsteadiness when standing and walking). The causes of cerebellar atrophy are hereditary diseases, autoimmune encephalitis, paraneoplastic syndromes, etc., which include hereditary spinocerebellar ataxia, multiple system atrophy, MERRF in mitochondrial encephalomyopathy, subacute cerebellar degeneration, anti-homer-3 cerebellar ataxia, etc., and some cerebellar atrophy is caused by cerebellar vascular lesions.

Cerebellar atrophy. There are both physiological and pathological causes. With the increase of age, cerebellar atrophy can not be avoided, which is a normal physiological phenomenon, pathological phenomena such as hereditary ataxia will appear cerebellar atrophy will be obvious or carbon monoxide poisoning, brain trauma may cause cerebellar atrophy, if it is pathological need to be timely**.