What to do if there is intestinal metaplasia, the difference between intestinal metaplasia and intes

I don't know if you found intestinal metaplasia in **, if it is found by gastroscopy, it depends on whether it is small intestinal metaplasia or large intestine metaplasia, if it is small intestinal metaplasia, dynamic observation is required, and gastroscopy should be done regularly to see the evolution. If it is colorectal metaplasia, it is generally considered to be a precancerous lesion and needs to be surgically removed as soon as possible to avoid cancer.

Intestinalization is intestinal gland metaplasia, and the main differences from intestinal metaplasia are as follows:

First, the form of lesions is different.

1. Intestinal gland metaplasia: the gastric mucosal epithelium is replaced by the epithelial tissue of the gland.

2. Intestinal metaplasia: gastric mucosal cells are replaced by intestinal epithelial cells.

Second, the reasons are different.

1. Intestinal gland metaplasia: caused by various benign gastric diseases or chronic gastritis.

2. Intestinal metaplasia: the gastric mucosal epithelium is transformed into small intestine or large intestine mucosal epithelial tissue containing parnett cells or goblet cells.

Third, the form is different.

1. Intestinal gland metaplasia: there are cup-Zheng dismantling cells secreting acidic mucus, absorption epithelial cells with striatal borders, and Paneth cells.

2. Intestinal metaplasia: stomach distention, stomach pain, acid reflux, heartburn or decreased digestive function, feeling of fullness, appetite, burning under the skin and limbs, etc.

Encyclopedia - Intestinal gland metaplasia.

Encyclopedia - Intestinal metaplasia.

Intestinalization is intestinal gland metaplasia, and intestinal metaplasia.

The main differences are as follows:

First, the form of lesions is different.

1. Intestinal gland metaplasia: the epithelial tissue of the gastric mucosal epithelium by glands.

replaced. 2. Intestinal metaplasia: gastric mucosal cells are infected by intestinal epithelial cells.

replaced. Second, the reasons are different.

1. Intestinal gland metaplasia: due to various benign stomach diseases.

Or chronic gastritis.

caused. 2. Intestinal metaplasia: gastric mucosa.

The epithelium transforms into epithelial tissue of the mucosa of the small or large intestine containing parnett cells or goblet cells.

Third, the form is different.

1. Intestinal gland metaplasia: goblet cells secreting acidic mucus, absorption epithelial cells with striatal borders and Paneth cells, etc.

2. Intestinal metaplasia: stomach distention.

Stomach pain, acid reflux, heartburn or decreased digestive function, feeling of fullness, decreased appetite, etc.

Encyclopedia - Intestinal gland metaplasia.

Encyclopedia - Intestinal metaplasia.

Atrophic gastritis is a severe gastritis characterized by atrophy of the mucous membranes of the stomach and reduction of glands; As the disease progresses, intestinal metaplasia occurs inside the stomach, and mild intestinal metaplasia can only be detected by pathological examination; Severe intestinal metaplasia can be detected by visual gastroscopy! It can be regarded as a precancerous lesion of the stomach, so it must be paid attention to and vigilant! Experts from the Gastroenterology Specialist Clinic of the Affiliated Hospital of Tianjin Armed Police Medical College said:

The intestinal metaplasia of atrophic gastritis can be divided into small intestinal metaplasia and large intestine metaplasia according to pathology, the former is slightly related to gastric cancer, and the latter is closer to gastric cancer! The occurrence of intestinal metaplasia in atrophic gastritis is closely related to the unstable and harsh physical and chemical environment of the gastric cell matrix! The differentiation of gastric parietal cells is poorly induced, and intestinal metaplasia of atrophic gastritis can occur, and intestinal metaplasia is not far from gastric cancer!

So what to do? At present, the outpatient clinic of the Department of Gastroenterology of the Affiliated Hospital of Tianjin Armed Police Medical College is using "Jinsha and Gastric San" to ** the problem of intestinal intestinal atrophic gastritis. In order to comprehensively improve atrophic gastritis, the armed police health system adopts biotechnology to preserve and improve a variety of active ingredients such as plant collagen, crude polysaccharides, and total flavonoids by traditional Chinese medicine digestion method, with low molecular weight, which can be perfectly combined with human cells to comprehensively sterilize and reduce inflammation, especially killing Helicobacter pylori and maintaining the balance of gastric flora; It quickly binds to the anisotropic protein in the exudate of the injured mucosa and widely covers the surface of the lesion mucosa, exerts a strong mucosal protective effect, reduces the attack factors of the mucosa, and promotes the recovery of the gastric mucosa. Replenish the nutrition of glandular cells, activate cell function, promote the shedding of shriveled cells, induce the regeneration of healthy cells, and restore the normal function of the spleen and stomach; At the same time, it activates the immune system, so that macrophages, lymphocytes, and immunoglobulins and other immune functions can be improved as a whole, so as to achieve atrophic gastritis, intestinal and other old stomach problems.

Intestinalization is an abbreviation for intestinal gland metaplasia. Due to the long-term existence of chronic inflammation, the gastric mucosa undergoes incomplete regeneration, and the atrophied glands are replaced by intestinal glands, which we call intestinalization. Intestinalization is more common in gastric atrophic inflammation, but superficial gastritis sometimes has intestinal cells in the fovea and superficial epithelium.

It is generally believed that intestinalization is an adaptive response of the body, and it is a low-value incomplete regeneration. Because well-differentiated adenocarcinoma of the stomach is often produced on the basis of intestinal mucosa, intestinal cancer has a certain relationship with gastric cancer. However, intestinization should distinguish between subtypes.

According to the mucus nature of intestinal cells, the presence or absence of Paneth cells, and the type of enzyme present, intestinization is divided into colon type and small intestine type. Colonic intestinalization is based on small intestinal intestinization and is closely related to gastric cancer.

The occurrence of intestinalization is very closely related to age, and the incidence of normal elderly people is quite high, so some people think that intestinalization is a degenerative change. The judgment of the significance of intestinization should be comprehensively considered in combination with age factors.

The full name of intestinalization is gastric mucosal intestinal epithelial metaplasia, which mainly refers to the oxyntic area or the surface of the gastric antrum, the gastric foveolar epithelium and glandular epithelium are replaced by intestinal epithelium, from chronic gastritis, atrophy to dysplasia, the middle stage of the gastric cancer cascade reaction process of adenocarcinoma, its cells come from the undifferentiated cells of the neck of the gastric intrinsic gland, which is a common lesion of the gastric mucosa, and is also a precancerous lesion of intestinal or diffuse gastric cancer.

1. Clinical manifestations.

Gastric mucosal intestinalization itself does not cause symptoms and is usually inadvertently detected by a gastric biopsy during upper endoscopy. Intestinalization can be accompanied by gastric acid deficiency, which can lead to bacterial overgrowth in the small intestine, and some patients may repeatedly experience symptoms such as epigastric discomfort, belching, heartburn, decreased digestive function, fullness, and decreased appetite. Regular gastroscopy, re-examination, and follow-up are required.

2. Clinical manifestations**.

The risk factors for intestinal metaplasia of the gastric mucosa are broadly similar to those for gastric cancer, and the common causes of gastric mucosal injury** are as follows:

1. Recurrent Helicobacter pylori infection.

2. Long-term smoking causes gastric bile reflux.

3. Long-term poor diet and living habits, such as alcoholism, smoking, and high-salt diet.

4. Combined with autoimmune diseases.

5. Vitamin C deficiency and folic acid deficiency.

6. Family history of gastric cancer.

Recommendation: Chronic atrophic gastritis is a common gastric disorder. Arteriosclerosis, insufficient gastric blood flow, and a penchant for tobacco, alcohol, and tea are all prone to damage the barrier function of the gastric mucosa and cause chronic atrophic gastritis.

In atrophic gastritis, the gastric mucosa atrophies and is replaced by intestinal epithelial cells, that is, intestinal metaplasia; If the inflammation continues to evolve, the cell growth is atypical, i.e., anatropic; Even cell proliferation and carcinogenesis. The clinical manifestations are only dyspeptic symptoms such as epigastric fullness, belching, and gastric insufficiency, and sometimes anemia can be caused by the destruction of gastric factors and vitamin B12 malabsorption. Endoscopy and biopsy are the only means to confirm the diagnosis.

Atrophic gastritis can be treated with medications** and should be checked regularly to prevent cancer.