Anxious about the genetics of epilepsy

Hello, the child born to a girl has little chance of getting sick, epilepsy has a certain genetic predisposition, and it can also be inherited from one generation to another, and the children of epilepsy patients are about 3-4 times higher than the normal population, but the farther their blood relationship, the smaller the chance of inheritance. Congenital epilepsy factors will only develop when they interact with acquired environmental factors, and as long as attention is paid to the prevention of various epileptic brain damage and adverse environmental factors, its offspring can avoid the onset of the disease.

There is a hereditary chance, but it is very small. If it is determined that it is inherited, it will never be good, and it can generally be good.

There is a hereditary probability, but it is not very high.

Hello, in fact, I was inherited by my mother, because my grandmother had it, so I had it, but my cousin and they didn't have my brother, but I don't know why I was the only one who inherited it, and I was very angry! After all, I'm a 20-year-old girl, and sometimes I feel so ugly when I get sick outside! And when I got sick, it was really dangerous if there was no one around, and I was injured when I fell several times.

So I have low self-esteem now, and I'm really afraid that others will dislike me.

First of all, we should understand that epilepsy is not an incurable disease, and there are many types of epilepsy, most of which are caused by the analysis of acquired environmental factors. Epilepsy is indeed hereditary, there is no doubt about it, but the heredity of epilepsy is uncertain. Therefore, as long as the patient himself can do a good job in the management of limb examination and nursing in a timely manner, it is possible to avoid heredity.

Genetic diseases in people with epilepsy are not so scary. The hereditary probability of epilepsy is small, so patients don't have to worry too much. But for parents with epilepsy, offspring are more likely to get the disease than normal children.

Therefore, patients must choose whether to have children or not if their epilepsy is under control.

Epilepsy has the potential to be inherited. Some of the causes of epilepsy are familial inheritance, but the probability is not very high. Qingsong is mainly caused by abnormal discharge caused by cranial nerve metabolism.

Epilepsy is more common in adolescents, once they reach the age of marriage and childbearing, whether they can get married and whether they can have children after marriage are very real problems in front of epilepsy patients and their relatives. And there are three main concerns about them: the first is whether epilepsy is hereditary?

The second aspect is the effect of pregnancy on epilepsy? The third aspect is whether taking anti-epileptic drugs will affect the fetus?

1. How do epilepsy patients treat their marriage and childbearing problems correctly?

Through the investigation and study of the twins of epilepsy patients, it is proved that epilepsy has a certain hereditary nature, and the size of genetic influence is related to epilepsy**. According to the survey data, 122 pairs of twins with at least one epilepsy patient, of which 44 out of 69 pairs of monozygotic twins both had epilepsy, accounting for 63%. Of the 53 dizygotic twin pairs, 5 had epilepsy, accounting for 9%.

Therefore, when choosing a spouse, patients with epilepsy should pay attention not to marry someone in the family or who has a history of epilepsy and febrile seizures, and should not marry someone who is close to the blood relationship.

2. When pregnant women with epilepsy are pregnant, the number of seizures will also increase.

This is mainly due to fluid retention after pregnancy, accelerated metabolism of drugs in the liver, and an increase in fetal tissue and placenta, resulting in a decrease in serum concentrations of antiepileptic drugs. The number of seizures is closely related to the increased severity of seizures and the degree of seizure control before pregnancy. Of course, there are also cases after pregnancy, and epilepsy control is better.

Therefore, epilepsy patients must be prepared before pregnancy, at least for more than 1 year, and strictly control the jujube calendar. In view of the fact that increasing the amount of anti-epileptic drugs may have adverse effects on the mother and fetus, the blood concentration of epileptic drugs should be measured frequently after pregnancy, and if it is lower than the effective drug level, the dosage can be appropriately increased, and the dosage must not be increased blindly.

3. Can anti-epileptic drugs cause malformations?

Although antiepileptic drugs have the potential to cause teratogenic children, they are not very common. You can't give up pregnancy just because of this, and you must not give up after pregnancy, otherwise epilepsy occurs frequently, and the danger is more harmful. In order to prevent the risk of teratogenesis, it is advisable to make full preparations before pregnancy, and it is more appropriate to get pregnant after epilepsy has been controlled for more than 3 years, and the drug has been withdrawn or reduced, of course, it cannot be postponed until more than 35 years old.

And the drug should be single, and the dose should be lowered to the lowest level possible to control the seizure.

If the patient has had a miscarriage, stillbirth, or has delivered an abnormal baby in the past, extra caution should be exercised if the patient has a new pregnancy. In general, the marriage and childbirth of epilepsy patients should be analyzed on a case-by-case basis, and adequate preparation before and after marriage, before and after pregnancy should be emphasized.

If you are unfortunate enough to suffer from epilepsy, but you still want to have a happy married life, then you need to work harder than others. Experts remind patients and friends that in fact, epilepsy patients do not need to worry too much about marriage and childbirth, and this problem can be completely solved medically, but patients and friends must make it clear to their lovers, do not deceive and conceal, and must accept formal and professional epilepsy**.

In the general population, the probability of a person developing epilepsy in their lifetime is about 2. If a parent has epilepsy, the proportion of offspring with epilepsy is only slightly higher than in the general population. If only the mother is sick, the proportion of offspring with the disease does not exceed 5.

If both parents have epilepsy, the offspring will have a higher rate of epilepsy. In summary, in the vast majority of cases, the offspring of people with epilepsy do not have the disease, although some types of epilepsy have an increased risk of epilepsy in their offspring.

Therefore, there is no need to worry too much that the offspring will suffer from epilepsy and dare not have children, and even if the offspring unfortunately suffers from epilepsy, most of them can be controlled by reasonable **, or even**.

Because of epilepsy, there are a lot of them. So. 1. Genetic factors of epilepsy. It's also minimal. Not all epilepsy is hereditary.

On the one hand, epilepsy may be congenital, which is easily inherited, and on the other hand, it may be acquired, such as traumatic infection, which is generally not inherited.

Don't talk about epilepsy genetics and change it. The most important thing is to distinguish what type of epilepsy it is. Diseases that are truly inherited from nature to the next generation, after **, the vast majority of genetic mutations have been repaired by DNA.

Therefore, it is necessary to go to a professional epilepsy hospital to find out what type of epilepsy it is, so as to know whether it is monogenic inheritance, polygenic inheritance, or X-linked recessive inheritance. Some epilepsy does have a genetic predisposition, but most don't. Idiopathic epilepsy is a generalized seizure disease with a familial genetic tendency, accounting for about 40% of the total number of various types of epilepsy, and the inheritance mode is monogenic inheritance and polygenic inheritance.

Generally speaking, if one of the parents is an epilepsy patient, the probability of epilepsy in children is naturally higher, if both parents have epilepsy, the probability is higher, in any case, the most important thing is to diagnose what type of epilepsy you are first, in order to assess whether the probability of the baby's genetic epilepsy is high, so it is necessary to treat the problem of epilepsy inheritance correctly.

For any epilepsy patient, the general epilepsy hospital will ask in detail about the health status and illness of the family members, if there are patients with the same seizures, or patients with hereditary diseases, experts will conduct family analysis, make a pedigree chart according to the laws of heredity, determine the type of heredity, and then carefully answer the question of whether the patient is inherited from epilepsy.

In general, a single gene is not sufficient to cause a single epilepsy phenotype, and the disease needs to be based on the combined effects of many genes and are interlinked. Therefore, first let your child find out whether it is a genetic predisposition to epilepsy, and then check whether it is monogenic inheritance or polygenic inheritance, these two types of inheritance, the type of seizures is also different, such as polygenic inheritance, pathogenic genes have no explicit or recessive distinction, the effect is small, the incidence is low, and the incidence in first-degree relatives is about about. The probability of heredity is still very small, and there is no need for patients and their families to be confused about the hereditary nature of epilepsy.

Do your parents or family have a history of epilepsy? Or you won't inherit it and you won't know it.

There is congenital epilepsy, so it should be hereditary! Acquired ones are not inherited.

Hello, epilepsy has a certain chance of being inherited, but it is not 100% hereditary. Patients with symptoms of epilepsy should go to the hospital as soon as possible, and with the continuous improvement of medical level, epilepsy can be carried out as long as it is systematic. At present, the most effective and advanced is neuronal multidimensional.