Where are the epileptic foci located in the brain10

Most patients with epilepsy have pathological changes in their brain tissue, known as epileptic foci.

In epilepsy, neuropathological changes are mainly localized sclerosis, localized scarring (after infection or trauma), meningeal adhesions, neoorganisms, etc., which lead to the disintegration of local brain tissue, blood supply disorders, changes in the composition of extracellular fluid in nerve cells, and disorders in tissue structure, so that the physiological function, biochemical structure and metabolism of cells are abnormal, laying the foundation for local cell electrophysiological changes.

Typical cerebral cortex epilepsy lesions have a central area and an annular median zone, replaced by scar tissue and glial hyperplasia, which no longer have nerve excitability and therefore no electrical activity. The annular median zone has a reduced number of nerve cells, and is degenerated due to insufficient blood supply and metabolic disorders, and is hyperexcitatory and has abnormal electrical activity, which is the area that causes epileptic discharge. The abnormal discharge propagates through the surrounding normal brain tissue, which forms the pathological basis for the seizures.

Epilepsy is divided into primary and secondary, and there is no clear location for primary epilepsy. Also known as idiopathic epilepsy. Secondary epilepsy is secondary to other diseases, such as cerebrovascular disease, brain tumor, brain cyst, etc.

In general, it is caused by various reasons that cause abnormal power generation in the brain. But the discharge site is different. It can be frontal, temporal, parietal, etc.

Epilepsy foci can be widely distributed in various areas of the brain, each person is different, the location of the lesion is also different, infection or inflammation infiltrates the normal brain tissue to form calcified foci, brain traumatic scar tissue formation, brain space-occupying lesions, etc. are the direct factors leading to abnormal intracranial electrophysiological transmission.

An epileptic lesion is the site of damage left behind during a seizure. Depending on the site of the injury, the location of the lesion is different.

A localized, diseased tissue with pathogenic microorganisms is called a lesion. They are like "bandits", hiding in a certain "corner" or part of the body, which harbors disease-causing bacteria or other pathogenic microorganisms. In addition to causing damage to the human body, lesions in the human body often cause trouble and cause lesions of distant organs.

This is medically known as "lesion infection". The lesion is generally present in the form of chronic inflammation, which can be quiescent or an active "base" of infection.

It is the pathological basis of the slow seizures, which refers to the direct or indirect cause of dementia discharge and seizures caused by brain tissue disturbances such as trouser changes or structural abnormalities, and CT and MRI can usually show pathological foci, some of which can only be found under the microscope.

The main diagnosis of epilepsy is based on symptoms and electroencephalogram, CT is mainly to find **, see what lesions are in the brain, even when there are no seizures, the results can be checked. It is recommended to do an electroencephalogram examination, the ordinary electroencephalogram monitoring time is relatively short, and the epileptiform discharge of the brain may not be captured, it is recommended to do a 24-hour ambulatory electroencephalogram or **EEG, which can greatly improve the positive rate of monitoring the epileptic discharge of the brain. Patients with epilepsy should limit their carbohydrate intake, limit potassium intake (foods low in potassium salt include rape heart, carrots, white radish, celery, pumpkin, tomatoes, eggplants, shallots, cucumbers, winter melons, loofahs, zucchini, pears, apples, grapes, pineapples, etc.) to increase magnesium intake (millet, corn, red beans, soybeans, dried tofu, green vegetables, celery, beef liver, chicken) should not eat more foods high in zinc (peonies, pancreas, liver, blood, lean meat, eggs, coarse grains, walnuts, peanuts, watermelon seeds, etc.).