Is hereditary ataxia so scary? Is ataxia hereditary more difficult to treat?

Hereditary ataxia is usually very scary, it is a hereditary degenerative disease of the nervous system, after the onset of the disease, the first appearance of physical instability, and when walking is more staggering, like drunk, as the disease progresses, there will be weakness in the hands, unsteady when holding things, and it will be accompanied by intentional tremor, nystagmus. It is necessary to detect it early and early to avoid delaying the best time, and active intervention in the early stage can delay the development of the disease and improve the quality of life. If there are some familial supply disorders, it is considered to be more serious, after all, this kind of family neuropathy may be caused by genes, or some chromosomal reasons can not be carried out**, and the heritability of the next generation is relatively large.

The consequences of hereditary ataxia are more serious, general ataxia will not affect the patient's life, but will have a huge impact on the patient's life, the patient must be active, go to the hospital in time, under the guidance of the doctor for relevant examinations, clear ** for **. Hereditary ataxia is usually very scary, it is a hereditary degenerative disease of the nervous system, after the onset of the disease, the first appearance of physical instability, and when walking is more staggering, like drunk, as the disease progresses, there will be weakness in the hands, unsteady when holding things, and it will be accompanied by intentional tremor, nystagmus. It is necessary to detect it early and early to avoid delaying the best time, and active intervention in the early stage can delay the development of the disease and improve the quality of life.

This disease mainly causes the clinical manifestations of ataxia in patients, the age of onset of patients is generally relatively young, clinical symptoms such as dizziness and unsteady walking can occur, and inflexibility of limb movement can occur, this disease is related to genetic defects, and patients generally have an obvious family history. It is recommended that patients seek medical treatment as early as possible, pay attention to improving the auxiliary examinations such as cranial MRI, and it is best to be able to carry out genetic screening to identify specific pathogenic genes. In addition, we must do a good job of prenatal counseling, do a good job of eugenics, and be sure to avoid the disease-causing genes.

Some patients with inherited ataxia can die. Juvenile spinal cord ataxia is a type of hereditary ataxia with a high incidence in Western countries and a rare incidence in Asia, with a population prevalence of 2.1 million. Autosomal recessive inheritance, with a high incidence of consanguineous marriage.

The onset is slow in adolescence, affecting both men and women, and symptoms progressively worsen. The main clinical features are progressive postural and gait ataxia, dysarthria, loss of tendon reflexes, loss of deep sensation, and positive symptoms. It is often accompanied by non-neurologic manifestations such as cardiac damage, diabetes mellitus, and skeletal deformities.

Most patients need to use a wheelchair for about 15 years after illness. The prognosis of the disease is poor, the age of death is 21-69 years, 90% of the causes of death are heart disease, and 10% are complications of diabetes.

At present, there is no ** that can completely stop the progression of hereditary ataxia, and the clinical ** of hereditary ataxia is still mainly symptomatic and supportive, and the main goals are to alleviate symptoms, alleviate the progression of the disease, and maintain the ability to take care of themselves in daily life.

1. Medication for simple treatment.

Serotonin 1a receptor agonists improve ataxia symptoms: buspirone can partially improve symptoms of mild cerebellar ataxia, and tandospirone** spinal-cerebellar ataxia type 3 is partially effective.

2. Levonatobopa: It can enter the central nervous system through the blood-cerebrospinal fluid barrier, and is converted into dopamine by dopa decarboxylase, thereby improving muscle rigidity, reduced exercise and other symptoms. Trihexyphenidyl has a blocking effect on choline receptors in the central nervous system, which can improve symptoms such as muscle rigidity and decreased exercise.

3. Anti-epileptic drugs: anti-epileptic drugs carbamazepine can better control the seizure symptoms of patients. At present, there is no effective symptomatic drug for the symptoms of dysarthria, which can be improved by speech correction training.

4. Drugs to dilate blood vessels and improve circulation: can dilate peripheral blood vessels and improve blood circulation, such as niacin, vitamin E, niacinate, cycloamygdals, pentoxifylline, etc.

5. Neuronal activation drugs: Coenzyme Q10 can promote neuronal metabolism and respiratory function, promote oxidative phosphorylation, and have the effects of antioxidant and protect the structural integrity of biofilms.

6. Vitamin drugs: they have a certain effect on maintaining the normal metabolic process of neurons and improving function. You can take B vitamins, vitamin E, etc.

2. Surgery**.

There is no surgery for this disease**.

3. Psychology**.

It mainly adopts cognition to change patients' irrational beliefs, improve cognitive distortions and negative thinking, arouse patients' positive emotions, and make them exert their own initiative.

4. Others**.

1. Cognitive dysfunction: At present, there is no effective drug**, and the early psychological strategies for patients include cognitive and behavioral intervention**, which is helpful for positive coping after the appearance of symptoms.

2. Nerve**: Patients with unstable gait can receive balance function training to help patients return to normal life.

Genetic ataxia is not a**, hereditary ataxia has a lot of genetic abnormalities in it. The most common sign of this is called hereditary spinocerebellar degeneration, which is a hereditary disease, and there is no particularly good clinical drug or intervention to improve the course of the disease, so it cannot be **. There are also a very small number of hereditary cerebellar ataxia, such as adrenal collapse of the spine cerebellar degeneration, which is related to the metabolism of fat chasic acid.

There are drugs that can reduce its symptoms, but the proportion of this part of the patients is relatively low, so most of the hereditary ataxia is not a specific drug**.

It is not difficult to treat, find the right doctor to prescribe the right medicine.

Ataxia is hereditary. For example, spinocerebellar ataxia and telangiectasia are caused by ataxia. Friedreich's hereditary ataxia is caused by genetic causes.

It is necessary to go to the hospital in time to distinguish whether it is a genetic correlation or an acquired cause. For spinocerebellar ataxia, genetic testing can be performed to determine whether there is a genetic connection.

There are many causes of ataxia, so ataxia is not necessarily genetic. There is a disease called spinocerebellar ataxia, which is caused by obvious genetic mutations, so this disease is said to be a genetic disease. At present, there is a lack of effective means, mainly for some training and some drugs to protect brain cells.

In addition, cerebellar hemorrhage, cerebellar infarction, and cerebellar inflammation can cause ataxia in patients, which is not caused by genetic mutations, but by some acquired factors. Therefore, ataxia caused by this cause is not hereditary, and it needs to be analyzed for specific diseases.

Ataxia is a clinical condition that is not inherited.

Only a subset of diseases that cause ataxia, such as hereditary spinocerebellar ataxia, which is a genetic disease, is an autosomal dominant inheritance, and can be inherited, often with ataxia drunken gait, unsteady walking, easy falling, lack of energy in both lower limbs, and increased tension.

In addition, other common diseases that cause ataxia are not hereditary diseases and do not appear hereditary, such as cerebrovascular diseases, including cerebellar infarction, cerebellar hemorrhage, cerebellar inflammation, cerebellar tumors, etc., as well as ataxia caused by certain drugs.

Ataxia is inherited for several generations, depending on the patient's specific situation, and if it is autosomal dominant, it may generally be inherited in the immediate family; If it is an autosomal recessive disorder, in general, the chance of inheritance depends on the patient's specific situation.

In addition, if ataxia is caused by some secondary factors, such as ataxia caused by lesions of the cerebellum or spinal cord due to intracranial infection, these patients are generally not inherited.

Others are due to nutritional disorders, such as ataxia caused by subacute combined degeneration caused by vitamin B1 or B12, which is generally not inherited.

There are also patients with alcoholic ataxia caused by long-term alcohol abuse, which is generally not inherited.

There is a certain probability, but it cannot be directly judged, this disease may also be inherited by recessive genes, it is not possible to judge whether the child will have this disease before pregnancy, after pregnancy can be judged by testing genes, if it exists, it is recommended that it is best to give up pregnancy. If you are not sure, you should go to a regular hospital for a check-up.

The hereditary probability of ataxia is very high, if one of the parents has a disease, the offspring have a 50% chance of developing this disease, therefore, the impact on the offspring is endless, and it is impossible to estimate how many generations can be inherited, therefore, it is generally recommended in medicine that patients with ataxia do not have children, so as not to have the condition of the offspring having the disease, ataxia is currently an incurable disease, and the patient will gradually lose the ability to move.

Ataxia syndrome features. Nystagmus, bards, dysmetria, tremor, and gait ataxia are the main signs of the cerebellum, and may be accompanied by dementia, pyramidal tract signs, and signs of spinal cord and peripheral nerve damage. Cognitive dysfunction:

At present, there is no effective drug**, and the early psychological strategies for patients include cognitive-behavioral intervention**, which is helpful for positive coping after the onset of symptoms, emotional care should be strengthened, and positive care should be given when there is no patient interest in things and low self-evaluation to help them regain confidence. Try to get rid of the monotonous lifestyle and be proactive and communicative.

Cerebellar ataxia is hereditary and more common than adulthood. The main manifestations are ataxia of the limbs, mostly heavier in the lower limbs, nystagmus and poetic speech. There are three types:

no family history, only cerebellar involvement, no intention tremor, possibly cerebellar cortical ataxia; If there is significant intention tremor, nystagmus, and late onset of dysphagia, it may be olive, pontine, cerebellar ataxia; Cerebellar dentate nucleus ataxia may be present if cerebellar ataxia is present with significant intention tremor, and lower extremity ataxia is mild or convulsive and myoclonus.

Brain ataxia can be inherited and is called hereditary ataxia. There is currently no cure-specific method, so the focus should be on prevention. Avoid marriage between close relatives, do a good job of premarital examination, people with a family history of the disease try not to get married or do not give birth after marriage, physical exercise should be strengthened during the course of the disease, to prevent premature bed rest and disability, the disease develops slowly, and the early stage is often not life-threatening.

Hereditary cerebellar ataxia is the most common type of ataxia. The pathogenesis is unknown, the lesions mainly involve the cerebellum, but the spinal cord and cranial nerves can also be partially affected, and the inheritance mode is autosomal dominant, and there is no significant difference in the incidence between men and women. **Principles, Symptomatic & Supportive**; Acupuncture & ****.

Overview of hereditary cerebellar ataxia (neurology) This disease is the most common of all reported ataxias. The pathogenesis is unknown, and the lesions mainly involve the cerebellum, but the spinal cord and cranial nerves can also be partially affected. The mode of inheritance is autosomal dominant, and there is no significant difference in incidence between men and women.

Clinical presentation. 1.Most of them start at the age of 30 to 60 years, and a few develop at the age of adolescence or 70 years of age. There is a family history of autosomal dominant inheritance, often with ataxia gait as the first symptom, unsteady walking, and easy falling. Thereafter, bilateral upper extremity ataxia may progressively develop; 、

2.Some cases may have dysphagia, aphonia, speech disorders, emotional instability, wisdom decline, etc., as well as diplopia, eye movement disorders, etc.

3.Weakness in both lower extremities, increased muscle tone, hyperreflexia or hyporeflexia, and positive pathological reflexes.

4.There are no cavus feet or cardiac abnormalities. Diagnosis is based on 1The age of onset is late, and there is a family history of autosomal dominant inheritance.

No. Ataxia is when there is no problem with the strength of the muscles themselves, but there is a problem with the coordinated movement of the muscles, and the patient is unable to maintain normal movements or support reflexes. Generally, it can be divided into four types: sensory ataxia, vestibular ataxia, cerebellar ataxia and hereditary ataxia.

Because different types of ataxia are different, there are also relatively large differences in methods and efficacy.

Ataxia is a neurological disorder that is acquired and has a very small chance of being inherited, so don't worry and treat it right.

The hereditary probability of ataxia is very high, if one of the parents has a disease, the offspring have a 50% chance of developing this disease, therefore, the impact on the offspring is endless, and it is impossible to estimate how many generations can be inherited, therefore, it is generally recommended in medicine that patients with ataxia do not have children, so as not to have the condition of the offspring having the disease, ataxia is currently an incurable disease, and the patient will gradually lose the ability to move.