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Synovial sarcoma** is mainly used to remove the tumor by surgery, and adjuvant radiotherapy and chemotherapy.
Synovial sarcoma accounts for about 5 10 of soft tissue sarcomas and is a malignant tumor with mesenchymal and epithelial biphasic differentiation with undetermined differentiation direction. The tumor is highly malignant, and the site of occurrence is mostly the large joints of the limbs. **Surgical resection of the tumor is the mainstay, and adjuvant radiotherapy and chemotherapy.
Early extensive resection of the oncology department to achieve a good effect, such as the tumor invades the blood vessels, the need to remove the blood vessels, the tumor resection is not complete, there will be a high local rate, adjuvant chemotherapy also has a certain effect, can increase the success rate of limb salvage surgery.
If synovial sarcoma responds well to radiotherapy and chemotherapy before surgery, the rate of postoperative resection after adjuvant chemoradiotherapy is lower. Even if the effect of adjuvant chemoradiotherapy is satisfied, the rate of local lesions in the proximal extremity and deep around the trunk is still high. Early localized lesions are mainly widely resected, and the effect is satisfactory.
Synovial sarcoma** Extensive amputation is required, and synovial sarcoma that is difficult to diagnose before surgery requires ganglion sac or marginal resection and then sent for pathological definitive diagnosis.
Learn about the disease. Synovial sarcoma.
Synovial sarcoma is a malignant tumor that arises from the soft tissues of the joints, synovium, and synovial membrane of the tendon sheath. It is common to have large joints in the limbs, and it can also occur on the muscle membranes and fascia of the forearms, thighs, and lower back. The main clinical symptoms are local swelling, lumps, pain, and limited activities.
Mainly surgical**...
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Editorial reviewer. Department of Orthopedics, Cancer Hospital, Chinese Academy of Medical Sciences.
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The main method of synovial sarcoma is extended excisional surgery, combined with chemoradiotherapy. Extended excision surgery is fundamental, and the first operation is very important, we need to expand the excision of the tumor in a standardized way, and at the same time place relevant landmarks, and place silver clips in the surgical area, so that postoperative radiotherapy can be guided. Radiotherapy can significantly reduce the rate of post-surgery, but there is a disadvantage that it may lead to edema of tissue fibrosis, which must be determined by the radiotherapy doctor.
Chemotherapy is a must, because the tumor has many seeds in the blood, this seed can not be removed with a scalpel, and pesticides are needed, and our pesticides refer to chemotherapy drugs, which enter the human body through infusion, at least inhibit the spread of tumors in the blood, and reduce the probability of metastasis.
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The most reliable way is to do surgery.
Surgery. Radiotherapy, chemotherapy.
It depends on the condition.
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There are three methods, the first is marginal excision. It is suitable for cases where the tumor is relatively large or adjacent to the blood vessels and nerves. The second is wide excision.
It is the most common method to remove the tumor and the normal tissue around it. The third type is ** excision, which mainly includes amputation surgery and so on.
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The best **plan for synovial sarcoma is surgery**, but the specific ** method depends on the actual condition, synovial sarcoma is a high-grade malignant tumor disease, and lung metastasis can also occur in the early stage.
The main symptom of synovial sarcoma is the rapid enlargement of the lesion in a short period of time, for the synovial sarcoma without metastasis and the lesion is small, it can be expanded and excised for the lesion, but for the larger lesion, amputation surgery can be taken.
In the case of metastasis, only palliative surgery** or radiotherapy with radioactive seed implantation** can be used, followed by chemotherapy, external radiotherapy and traditional Chinese medicine**.
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Synovial sarcoma is not a particularly big disease. All major hospitals should be treatable.
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What are the reliable protocols for synovial sarcoma in modern medicine? For modern medicine, the general choice is minimally invasive or very small, which will make you conservative, do not have surgery, then take medicine, then take medicine, and then eliminate these two are more common.
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Traditional Chinese medicine has a good method.
To use an analogy: any cancer, just like a seed, and your body is like the soil, whether the seed grows or not depends entirely on the soil, not the seed itself, no matter how good the seed is, the soil is not suitable for it will never grow, how to improve the soil is the subject of our research today, and breakthroughs have been made. And our technology today is also a breakthrough in the world.
Surgery is not recommended unless the tumor is too large**.
The patient, Mr. Hong, has used surgery, chemotherapy, biology, etc., but before coming to the hospital, there were two retroperitoneal sarcomas of 8 cm, and the tumors disappeared completely after 45 days.
The purpose of chemotherapy is to kill cancer cells in the body, but at the same time as killing cancer cells, good cells are also killed by dormant cancer cells, that is, cancerous cells cannot be killed, and there will be ** or metastasis to ** see.
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Most are large, fast-growing tumors that grow on the thighs, buttocks, shoulder girdles, or upper arms. The small one is a superficial lump on the back of the hand and the dorsum of the foot. There is mild pain and tenderness, sometimes without obvious symptoms.
Slow growth, diffuse swelling, local** redness, elevated skin temperature and venous distension, limited movement. Some grow rapidly at the beginning, show remarkable results, and metastasize occurs earlier. Synovial sarcoma has more chance of lymph node metastasis than other soft tissue sarcomas.
1.The clinical manifestations are more common in adolescents and middle-aged patients, more in men than in women, and the most common sites are near the major joints, mainly in the knees, followed by near the ankles, hips and shoulder joints. More than half of all illnesses occur in the lower extremities, and one in a quarter of cases occurs in the upper extremities.
The neck and trunk are less, the tumor grows invasively, it is easy to ** after resection, the course of the disease is different, it is a ** mass at first, it grows and there are different degrees of pain, and the general tumor can invade the surrounding bone tissue. When the tumor is large, it affects joint mobility. Synovial sarcoma presents with a mild, soft-tissue mass located deep within the deep fascia.
Slowly enlarging, adjacent joint masses are the main clinical manifestations. Physical examination reveals that the mass is firm in texture and fixed to deep structures. It is the most common soft tissue sarcoma near the hands and feet, and synovial sarcoma in this area is often mistaken for a ganglion cyst.
2.The natural history of the primary mass grows slowly, initially pushing against adjacent soft tissues and bone, and then invading them. Lumps that occur in muscular areas of the limbs usually grow more rapidly than lesions that occur on the dorsum of the hands and feet.
The incidence of regional lymph node involvement is significantly higher than that of other soft tissue sarcomas, and the distal site metastasizes predominantly to the lungs (lesions usually present as stage B sarcomas). Lesions in the hands and feet progress more slowly and ** than lesions that occur in the proximal extremities and trunk shafts.
3.It occurs in the paraarticular tissues of the limbs and in the peritendinal tissues of the hands and feet. It tends to occur around the calf and knee joints, and tumors can invade the tendon sheath and bursa.
Often adjacent to the joint, but rarely occurs within the joint. Lesions located in the upper extremities, more commonly on the volar side. Synovial cell sarcoma is also more common in the feet.
Based on the clinical presentation, combined with imaging, the disease should be considered, and the diagnosis should be confirmed by biopsy and pathology.
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Synovial sarcoma is a relatively common soft tissue tumor, accounting for about 5 10 of all soft tissue tumors, and is easily confused with other soft tissue tumors. The 5-year survival rate of intermediate- and high-grade tumors was 36 76, while that of low-grade tumors was 20 30, and the prognosis of synovial sarcoma of the extremities was better than that of those occurring in other sites.
Synovial sarcoma is mainly seen near the major joints of the limbs, and a multidisciplinary approach should be taken, and extensive tumor resection and peripheral tissue excision are the preferred methods for synovial sarcoma. For patients with masses larger than 5cm, positive postoperative margins, and well-differentiated patients, radiotherapy should be supplemented after surgery to reduce the local ** rate. For ** tumors, re-resection is recommended if possible, and postoperative adjuvant radiotherapy.
Interstitial brachytherapy can be used for sites that have been radiotreated.
Try to relax and go to a specialist cancer hospital as soon as possible to replenish**.
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1 The literature reports that early detection of synovium-based sarcoma can be **, but only a few cases have been reported, and most patients can only prolong their lives as much as possible and improve their quality of life. Once synovial sarcoma is diagnosed, hospitalization is recommended. Hospitalization can be further based on the degree of disease progression of the patient.
2. Synovial sarcoma is a common tumor, usually occurs in the joints, fascia, and muscle membranes of the limbs and back, usually in the joints where synovial sarcoma is common, a bulge can be seen large or small, this mass is a malignant mass, is a very serious disease.
3. If the sliding membranous sarcoma collapses, there will be a local mass growing rapidly, compressing the blood vessels and nerves, affecting local limb activities, the biggest harm is the occurrence of distant metastasis, especially lung metastasis, once the lung metastasis, will cause organ failure, threatening life, how long can you live in the specific advanced stage depends on the condition and metastasis.
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