What is the most accurate method to detect Helicobacter pylori?

The urea breath test is relatively accurate. This test is painless, sensitive, and has a high detection rate. The cost is also low, but there are certain drawbacks. Radioactive. The impact on children as well as pregnant women is significant.

The best and most accurate way is to go to the hospital for a gastroscopy, which is more accurate.

The most convenient and accurate way is to go to the hospital and use professional Helicobacter pylori test strips to determine whether you are infected with Helicobacter pylori.

The detection method of Helicobacter pylori breath test is more standard, the subject takes carbon-13 or carbon-14 labeled urea, the characteristic urease secreted by Helicobacter pylori will break down this urea, and the carbon 13 or carbon-14 labeled carbon dioxide produced is exhaled from the lungs after blood circulation, and the carbon dioxide gas exhaled by the subject is collected and detected on a highly sensitive instrument, if the instrument detects the carbon 13 or carbon-14 labeled carbon dioxide in the exhaled breath, it can determine the presence of Helicobacter pylori in the stomach of the subject.

The urea breath test has obvious comprehensive advantages: the method is simple, and the requirements for the test environment, test equipment and operator skills are not high; Easy sampling, good patient compliance; Compared with invasive testing, it overcomes the problem of positive missed diagnosis that may be caused by the "focal-like distribution" of Helicobacter pylori in the stomach.

There are several ways to check for H. pylori:

1.Helicobacter pylori antigen test: A sample of stool is collected to detect H. pylori antigen in the stool. This method is simple and non-invasive, but false-negative results may be present. Suitable for general routine screening.

2.Urea breath test: indirectly determines H. pylori infection by measuring urease activity in exhaled breath. This method is non-invasive and highly accurate. Suitable for initial screening and ambulatory monitoring.

3.Serum antibody testing: Infection is determined by measuring the level of Helicobacter pylori antibodies in serum, including anti-H

Pylori IgG, IgM and IgA, etc. This method is widely used, but it does not distinguish between active and old infections. Suitable for primary screening and diagnosis.

4.Helicobacter pylori culture: the presence of H. pylori is confirmed by taking a biological tissue sample of the gastric mucosa for culture.

This method requires gastroscopy and is invasive, but it can give accurate results. Suitable for diagnostic and bacterial susceptibility testing.

5.Helicobacter pylori PCR test: Molecular biology techniques are used to detect specific genes of Helicobacter pylori to determine the status of infection. This method is highly accurate and sensitive, allowing for rapid diagnosis of infection. It is suitable for early diagnosis and evaluation of the effect.

When choosing a method to detect fibril burning, factors such as personal circumstances, symptoms, physician recommendations, and medical resources should be considered. For initial screening or testing for non-specific symptoms, a H. pylori antigen test or a urea breath test may be used. For accurate diagnosis or drug susceptibility testing, H. pylori culture or PCR testing is generally required.

If in doubt, it is advisable to consult a doctor for more accurate advice.

Common methods for detecting Helicobacter pylori include:

Detection of urease activity in exhaled gas: People drink a solution containing urea and a marker substance, such as carbon or nitrogen, which breaks down urea and releases a marker if it is present in the stomach. The presence of H. pylori infection can be confirmed by measuring the amount of marker material in the exhaled gas.

Serum antibody testing: Infection status is determined by testing for H. pylori-specific antibodies in a patient's blood. This approach can be used for initial screening and to determine a past history of infection, but it cannot distinguish between active and past infection.

Antigen detection in stool: Infection status is determined by testing for H. pylori antigens in a patient's stool. This method is simple, non-intrusive, and highly accurate.

Histopathological examination: through gastroscopy and obtaining gastric mucosal tissue specimens, and then histological examination of the specimens to determine whether there is Helicobacter pylori infection in the tissue. This is the "gold standard" method for confirming the diagnosis of H. pylori infection, but it requires gastroscopy and is an invasive test.

Breath test with histology: This method combines a breath gas test and a gastroscopy histology. A breath gas test is performed first, and if the result is positive, a gastroscopy is performed to obtain a tissue sample for further diagnosis.

Each of these tests has its own advantages and disadvantages, and depending on the specific situation (e.g., severity of illness, financial conditions, medical resources, etc.), doctors will choose the appropriate test to confirm the diagnosis of H. pylori infection. Consult your doctor for detailed consultation and advice on how to choose the most appropriate test.

Helicobacter pylori is generally not self-detectable, Helicobacter pylori is a common anaerobic bacterium that can survive in the human body's gastric mucosal tissue, and if it does not reach a certain degree of destructiveness, people cannot perceive its existence. Generally, after causing great damage to the gastric mucosal tissue, causing gastritis, gastric ulcer and other diseases, it can only be found by going to the hospital for relevant examinations. The main methods for detecting Helicobacter pylori include blood antibody test, urea breath test, fecal antigen test, gastric biopsy, etc.

1. Blood antibody test: mainly to draw blood from the vein of the arm, and then conduct laboratory testing to check whether there is Helicobacter pylori antibody in the blood;

2. Urea breath test: the most commonly used method to confirm the diagnosis of Helicobacter pylori, including carbon 13 and carbon 14 types, mainly by blowing up balloons or blowing bubbles into bottled liquids to collect breath samples, and observe whether they contain Helicobacter pylori through breath samples at different times;

3. Fecal antigen test: put the collected feces into a dry container, and then conduct laboratory tests to determine whether there are Helicobacter pylori antibodies;

4. Gastric biopsy: Generally, endoscopes are used to collect tissue samples from the stomach and duodenum and test them in the laboratory to observe whether there is Helicobacter pylori. It can detect not only the presence of Helicobacter pylori, but also the presence of inflammation, atrophy, ulcers and other lesions.

Therefore, when Huaifan or Chong suspects that he has Helicobacter pylori infection, or has abnormal symptoms in the stomach, it is not recommended to deal with it by himself, and it is recommended to go to the hospital in time to improve relevant examinations to find out whether there is Helicobacter pylori infection.

Carbon 13 breath test, which is performed on an empty stomach or two hours after a meal. The patient has not taken sensitive drugs such as antibiotics and secret medicine in the past month, otherwise the test result will be falsely negative. Carbon 14 breath test, carbon 14 breath test is a method used in clinical practice to detect H. pylori infection.

The test subjects need to take one urea capsule with about 20 ml of cold boiled water on an empty stomach and sit still for 25 minutes.

Do a C14 or C13 breath test. This method is to swallow a urea capsule containing 14 or 13, blow vigorously every 15 minutes, detect the color change of the reagent, and determine whether there is Helicobacter pylori infection in the stomach. Gastroscopy.

In the gastroscopic antrum, Helicobacter pylori generally grows here, and the mucosa is tested for rapid urease, or the mucosa is taken for bacteriological testing, which is somewhat traumatic. Blood was drawn to check for Helicobacter pylori antibodies, and a positive antibody result indicates that there is Helicobacter pylori infection, but it is possible that there was a Helicobacter pylori infection in the past, and now the patient is also positive and cannot be distinguished. The stool test for Helicobacter pylori antibodies is the same as the third method, and the results of those who have been infected in the past are also positive.

Breath test refers to swallowing urea containing carbon-13 or carbon-14 elements into the stomach, urea reacts with urease produced by Helicobacter pylori to produce carbon dioxide, carbon dioxide is absorbed from the gastrointestinal tract, exhaled from the lungs, exhaled gas, and the exhaled gas is collected to detect its carbon-13 or carbon-14 content to determine whether there is Helicobacter pylori infection in the body;

If there is a history of Helicobacter pylori infection, Helicobacter pylori antibodies can appear in the blood, and whether there is Helicobacter pylori infection in the body can be indirectly judged through antibodies; The rapid urease method, that is, during gastroscopy, the mucosa in the stomach is taken for a rapid urease test to determine whether there is Helicobacter pylori infection in the gastric mucosa; During histopathological biopsy, special staining can be used to observe the presence of H. pylori infection in the stomach during histopathological biopsy.

First of all, you should take a blood test or breath sampling test, and you can also test the gastroscopic material, these three experiments are still more reliable and objective, you should often go to the test, otherwise it will cause the onset of other diseases.

You can choose to do gastroscopy, breath sampling, blood drawing, urine test, stool test, these methods can accurately detect Helicobacter pylori.

Blood grouping tests can be performed, saliva tests can be performed, urea breath tests can be performed, gastroscopy can be performed, and carbon-14 tests can be performed.

Recently, I felt a pain in my stomach, a little swollen and uncomfortable, I felt like I was full after eating something, and my friend came to my house and said that my symptoms may be Helicobacter pylori, and I had never heard of this disease before the postponement. So, how do you need to test for Helicobacter pylori?

1.First of all: go to the hospital and tell the doctor that you want to test for "Helicobacter pylori", all you need to do is go to a room with the relevant tests, and the doctor there will ask you to "exhale" into some device.

Blow some air, and then they will test the gas composition and wait for the results of the test instrument for like 10-20 minutes.

2.Second: the C14 breath test is often used as a marker because C14 is very stable.

In the Helicobacter pylori C14 breath test, after the subject takes urea C14 capsule orally, if there is Helicobacter pylori in the stomach, the urease produced by it can quickly decompose urea into carbon dioxide and ammonia, and the carbon dioxide enters the lungs through the blood and is excreted from the body.

3.Finally: C13 blowing test, because the HP bacteria have urease in it, when it encounters swallowed 13C-urea in the stomach, it will break it down into 13CO2, and 13CO2 is absorbed through the gastrointestinal tract and reaches the lungs through blood circulation and is excreted with exhalation.

We only need to disturb the collection of exhaled air and measure the 13C-labeled 13CO2 in it to accurately prove whether there is HP infection.

Precautions. Diseases such as Helicobacter pylori need to go to the hospital for formal examination, so that the disease can be effectively detected and targeted.