What are the two Achilles heels of the new coronavirus?

<> was happily going home for the New Year, but no one expected such a thing to happen! At the root of all this is the emergence of the new coronavirus. This virus is scary and scary because it is contagious, and it is transmitted from person to person, as long as you have been in contact with this kind of patient, you will be infected with this virus!

The pneumonia caused by the novel coronavirus is an acute pneumonia caused by a novel coronavirus that has not been previously found in humans.

The new coronavirus has an "Achilles' heel"! Keep these 2 ways in mind to "destroy" it!

Method 1: Death can be achieved by high temperatures.

To put it simply, why does meat need to be stewed at high temperatures? On the one hand, it is hoped that the meat products will be completely cooked, and on the other hand, high-temperature sterilization will kill some viruses and bacteria in the meat products!

With the research of experts on the new coronavirus, this virus is afraid of high temperatures! As the temperature increases, the activity of the virus decreases! Slowly it loses its contagiousness.

What we can do is actually very simple, drink more hot water in life, cook and cook, especially meat products, must be completely cooked, and eat less raw and cold food. When the weather is good, take out the bedding to bask in the sun, which can effectively prevent the new coronavirus.

Method 2: Disinfectants and alcohol can destroy the virus.

Recently, colleagues who have been working have noticed that there are cleaners regularly disinfecting the stairwells and pressing the elevator buttons every day! Therefore, friends at home can spray disinfectants indoors to kill viruses and bacteria in the air.

Or you can use more than 75% alcohol to apply it to the surface layer to destroy the virus, so that the virus and bacteria lose their infectivity!

We know the "weaknesses" of the new coronavirus, these are external factors, and in addition, in daily life, it is necessary to avoid contracting the new coronavirus.

1. Keep exercising. Although it is said that you will not go to a crowded place, you can also exercise properly at home. Exercise can speed up the body's metabolism, promote the peristalsis of the stomach and intestines, and can timely expel the viruses and bacteria in the body to improve the body's immunity.

2. Do a good job of isolation. Reduce going to crowded places, and if you have to go out, be sure to wear a mask and avoid face-to-face when talking, which can effectively prevent the other party's droplets from splashing on your face.

3. Eat a balanced diet. Eat well, eat plenty of fruits and vegetables, and drink plenty of water.

hours of sleep time. A good night's sleep is a prerequisite for good health! Sleep well to enhance your resistance to the virus!

Although the new coronavirus is "ferocious", it has these four weaknesses, and the sooner it is known, the better it is to prevent it.

First of all, experts found that the new coronavirus is afraid of high temperatures, and under low temperature conditions, the new coronavirus is easy to survive, therefore, during the epidemic prevention period, try to cook food at high temperatures, and secondly, use alcohol disinfection with a concentration of more than 75%, the new coronavirus will soon lose its activity, there is no resistance to ultraviolet rays, when ultraviolet rays irradiate the new coronavirus for about ten minutes, it can play a role in sterilization and disinfection.

The first point is that high temperatures can kill people, and the second point is that disinfectants and alcohol can destroy viruses. And in normal times, you must keep exercising, and then reduce going to crowded places, eat more fruits and vegetables, and then ensure enough sleep.

It can die at high temperatures, and can be sprayed indoors with disinfectant, which can kill viruses and bacteria in the air. You can use more than 75% alcohol to apply it to the surface layer to destroy the virus and make the virus and bacteria lose their infectivity!

The lungs of people are the most vulnerable to attack.

The new coronavirus attacks the weakest part of the human body, and whichever part is problematic, it will enter first.

The novel coronavirus is sensitive to ultraviolet light and heat, and lipid solvents such as 56 degrees Celsius for 30 minutes, ether, 75 ethanol, chlorine-containing disinfectants, peracetic acid, and chloroform can effectively inactivate the virus.

This year's New Year kicked off with the novel coronavirus, which has also affected the normal lives of many people. The new coronavirus is characterized by many transmission routes and a wide range of transmission, so it can wreak havoc across the country in a short period of time, making it difficult to prevent it. Next, I would like to introduce to you what we, as ordinary people, can do in the face of this ferocious epidemic.

1. Don't go out at home We all know that the epidemic spreads quickly from person to person, so it is best for us not to go out and avoid contact with potentially infected patients. Although many people can't hold back the boredom at home, we must think about the overall situation and not cause trouble to the motherland. <>

2. The main way of transmission of the epidemic is droplet transmission, so wearing a mask is the best way to avoid it. Everyone must remember to wear a mask when they are forced to go out, although the mask will be stuffy, but for the sake of safety, it is still not allowed to be careless. <>

3. Don't gather if you have nothing to do During the epidemic, many epidemics will lead to large-scale spread because of gatherings, so everyone should not gather with relatives and friends at home to avoid group infection with the new coronavirus. Although we as ordinary people cannot fight on the front line like medical workers, we must try not to cause trouble to them, so it is best for everyone to stay at home, do not go out, do not gather, and contribute to the fight against the epidemic. <>

I believe that as long as we are united, the virus will be completely eliminated, let us wait until the spring flowers bloom and the whole country celebrates, and then everyone will take off their masks and celebrate together.

It is characterized by droplet transmission, with an incubation period of 2-14 days after infection, and the clinical manifestations are: fever, fatigue, dry cough, and gradually dyspnea, and shock in severe cases.

It is very contagious, and once it occurs, it changes very quickly, making people very sick. This disease is very lethal, and the sequelae of curing are also large, and the probability of ** is not small.

The novel coronavirus is mainly transmitted by droplets and contact. It is not heat-tolerant and can both inactivate the virus when heated at 56 degrees Celsius for 30 minutes.

The latest discovery is that coronaviruses have an Achilles' heel, and the Achilles' heel of coronaviruses is that when they interfere with the process of "frameshifting" ribosomes by coronaviruses, they can inhibit the virus's ability to replicate.

1: New research discovers the Achilles' heel of coronavirusesA research team composed of a number of foreign universities has published a new ** article in the journal Science, which has discovered the "Achilles' heel" of coronaviruses, including the new coronavirus. This study successfully revealed the interaction between the viral genome and ribosomes in the process of "frameshift" for the first time, and found that the virus has "fine control" over the ribosome "frameshift" process, indicating that if it can interfere with the "frameshift" process of the coronavirus, it can effectively inhibit the replication ability of the virus, and then develop related drugs to fight the new coronavirus.

2. The pathogenic principle of the coronavirusIf you want to deal with the coronavirus, you need to have a clear understanding of the pathogenic principle of the coronavirus. Coronaviruses are unable to reproduce to produce offspring, and need to constantly replicate themselves by infecting normal cells, and then infect other cells, and so on, when the number of infected cells exceeds a certain number, the body will not be able to function properly.

After the coronavirus enters a normal cell, it uses the cell's own ribosomes to synthesize proteins needed by the virus. In normal cells that are not normally infected by the virus, ribosomes read their own RNA information and then synthesize normal proteins. When the coronavirus enters the cell, it interferes with the normal position of the cell to read the RNA, resulting in a "frameshift" when the cell reads, and finally synthesizes the protein required by the coronavirus.

Relevant research experts said that if the RNA sequence of the synthetic coronavirus protein can be captured, the RNA sequence can be targeted and inhibited through compounds, thereby preventing the coronavirus from replicating in the body.

Three: The preventive measures of the new coronavirus, including the new coronavirus, have not yet appeared in the world that can be effective, but it is believed that with the continuous progress and development of human medical technology, there will be drugs that can be effective in the future. Until then, the most important way we can control the pandemic is to prevent infection, and the most effective way to prevent infection is to get vaccinated.

When the human body is vaccinated against the new coronavirus, it will continuously produce antibodies against the virus in the body, and once the new coronavirus is found to enter the body, it can be detected and eliminated in time, which can reduce the situation of the new coronavirus infecting the body. When the vaccination rate of the whole population reaches 70-80%, a herd immunity barrier can be built, which can prevent the occurrence of mass infection, and then control the development of the new crown virus epidemic, which is the main reason why many countries and regions around the world are vigorously encouraging people to get vaccinated.

For the first time, this study has successfully revealed the interaction between the viral genome and ribosomes in the process of "frameshift", and found that viruses have "fine control" over the process of ribosomal "frameshift", which is expected to promote the development of drugs that inhibit viral replication by interfering with the "frameshift" process. The study also showed that a molecule called merafloxacin is a compound that better inhibits the "frameshift" process. It can reduce the titer of the new coronavirus by 3-4 orders of magnitude and is not toxic to cells.

Fluoroquinolones inhibit the "frameshift" efficiency of the coronavirus and other coronaviruses. This study shows that a molecule called merafloxacin is a compound that better inhibits the "frameshift" process. It can reduce the titer of the new coronavirus by 3-4 orders of magnitude and is not toxic to cells.

The transfer of ribosomes by the coronavirus is a very delicate control. If this control can be disrupted, the virus can naturally be suppressed.

The Achilles' heel is that it spreads very quickly, and the incubation period is very long, and there is a great possibility of mutation.

The discovery of the fatal weakness of the new coronavirus can be said to be a gratifying thing, and the virus can only replicate after infecting the cell and the host, and can continue to survive. Because of such characteristics, scientists have conducted further research. They found that there is a 'frameshift' relationship between viruses and accounting, and that viruses have "fine-grained control" over the ribosomal "frameshift" process.

We all know that normal ribosomes follow RNA movement, and when three RNA letters (i.e., three genetic codes) are read at a time, when only two of them are moved, the ribosome misalignment is called 'frameshift'. If it occurs in healthy cells, it will lead to dysfunction of cellular proteins, and the new coronavirus relies on 'frameshifts' to regulate the function of viral proteins.

With this new discovery, as long as we interfere with the 'frameshift' of the virus, so that the virus does not have a way to reduce the number of viruses, it should not be difficult to eliminate the active virus and really kill the virus without affecting the health of the body. It can be said that this finding is very important and gratifying for the global epidemic.

Recently, there have been several local cases of new coronavirus infection in Liaoning, and because they are all asymptomatic people, there are certain difficulties in screening. Due to the emergence of such local asymptomatic infections in China, everyone's nerves became tense again, and they began to sign up for vaccination, from the very beginning of indifference and fear of sequelae of vaccination. Up to now, everyone has started to make appointments and queue up for vaccination, and everyone's attitude has changed a lot.

I still remember that at the beginning, everyone was afraid of vaccination, and in order to encourage vaccination, various places used various daily necessities to mobilize everyone's enthusiasm. Nowadays, most people are aware of the dangers and potential risks of infection, and it is more practical to protect themselves from infection than to get vaccinated.

Through complex biochemical experiments, the researchers managed to capture ribosomes at the "frameshift" site of the coronavirus RNA genome. Then, cryo-EM studies showed that the viral RNA formed a pseudoknot structure and stayed at the entrance of the ribosomal mRNA channel, creating tension in the mRNA and promoting the occurrence of "frameshift", while the nascent viral polyprotein formed a significant interaction with the ribosomal channel. That is, the interaction between the false knot and the ribosome causes the occurrence of "frameshift".

The discovery that viruses have "fine control" over the ribosomal "frameshift" process is expected to facilitate the development of drugs that inhibit viral replication by interfering with the "frameshift" process.

It is a weakness formed by this cell, and if this place is breached, in fact, this bacteria and viruses will not exist.

It's that we're particularly afraid of heat, and this virus is particularly afraid of high calories, and it's also very afraid of alcohol, so this can also make it easier for us to eliminate the virus.