How do you get gout, what is gout?

Gout is divided into three parts, including early control and alleviation of acute arthritis symptoms; Reduce the amount of uric acid in the blood to prevent further deposition of uric acid in tissues; Prevent the formation of uric acid stones, reduce severe joint damage and kidney damage. In the case of acute attack of gout, early use of non-steroidal anti-inflammatory drugs, colchicine and glucocorticoids can effectively anti-inflammatory and analgesic and improve the quality of life of patients. At this stage, it is very important to have anti-inflammatory and analgesic treatment within 24 hours.

Gout disease has a distinction between primary ventilation and secondary ventilation, and its ** is also different, which is briefly described as follows:

Primary gout.

1) Genetic factors Clinically, gout has a significant familial genetic tendency, and the detection rate of relatives of gout patients with asymptomatic hyperuricemia is significantly higher than that of non-gout patients. Gout is closely related to other genetically predisposed metabolic diseases (obesity, hypertension, hyperlipidemia, diabetes, etc.). It has been identified that there is a genetic basis for mutations in enzyme genes that cause changes in enzyme activity in purine metabolism that leads to excessive uric acid production.

2) Environmental factors Overeating, alcoholism, and excessive consumption of purine-rich foods are common causes of gouty arthritis exacerbations. The improvement of socioeconomic conditions and the increase in the prevalence of metabolic diseases such as obesity and hypertension have also increased the prevalence of gout.

2.Secondary gout.

1) Causes excessive uric acid production in the body** such as leukemia, lymphoma progression, especially after chemotherapy, polycyte vera, etc. After severe trauma, crush injury, major surgery.

2) Causes decreased renal uric acid excretion** such as severe hypertension and eclampsia that cause reduced renal blood flow, affecting uric acid filtration; Renal failure from any cause; Congenital tubular dysfunction, Fanco syndrome, Barthes syndrome, etc.; Metabolic abnormalities that affect the secretion of uric acid in the renal tubules, such as ethanol poisoning, excessive starvation, ketoacidosis, lactic acidosis, etc., can cause an increase in the content of organic acids in the blood and inhibit the secretion of uric acid in the renal tubules; Some medications, such as ethambutol, can cause hyperuricemia.

3) Factors influencing the change of blood uric acid concentration Long-term use of diuretics**, severe prerenal dehydration, blood concentration, increase blood uric acid concentration.

I also have gout, two a day.

I couldn't walk on my legs and went to the hospital to say my urine.

High acid, calcium deficiency and so on, what the doctor said are more professional, but the medicine prescribed is not good, and he eats a lot of money.

Nothing worked. My neighbor's Sister Zhang.

Introduced me to a better medicine.

Bought online, his 68034576

I told him about my condition and the medicine I was given after the diagnosis.

His medicine is not cheap, and he was reluctant to spend money at first and didn't dare to buy it.

Later, the pain was really bad, so I bought it, and after eating it for 5 days, I felt better, and finally took a total of 2 courses of treatment, and now it doesn't hurt.

Now there are more and more people with gout, alas.

Gout is a metabolic disease, because of abnormal uric acid metabolism, the concentration of uric acid in the blood continues to be high, resulting in the formation of uric acid crystals deposited in the joints, and then caused by gouty arthritis.

Causes of gout: Eating high-purine foods, such as meat, beans, etc., drinking alcohol, exercising less, staying up late, etc.

Gout is generally experienced by older people, men should pay attention to their bodies when they are young, and women generally have gout after the age of 50. In terms of prevention, the following points can be done: eat less high-purine foods, such as meat, beans, etc., it is recommended to quit alcohol, drink more water, insist on appropriate exercise every day, do not work too hard, and do not stay up late.

According to statistics, there are about 2.1 million to 9.4 million gout patients in China, which is a huge number. Gout has become a stubborn disease in modern society, just like metabolic diseases such as hypertension, high blood sugar, high blood lipids, and obesity. In fact, gout is often associated with the above diseases, increasing the risk of cardiovascular and cerebrovascular diseases.

So, how does gout come about, how to effectively avoid gout, and how to better manage gout?

First, what is gout?

Gout is an inflammation of the joints caused by the deposition of urate in the blood cavity, causing redness, swelling, heat and pain in the joints. Gout is a term that describes the patient's performance well. The first is that the pain comes like the wind, there may have been no signs before, and the pain started quickly; The second is that it is really "painful crazy", many gout patients have described wanting to cut off the painful part, which shows how bad the pain is.

Second, why does urate get into the joint cavity?

Urate deposition in the joint cavity is mainly caused by high concentrations of uric acid in the blood. So where does uric acid come from? Uric acid is produced from purine metabolism in the DNA components of cells.

20% of the uric acid in our blood comes from the purines in the food we eat, and the rest is produced by our own metabolism in the body.

Third, what is the cause of the increase in uric acid concentration?

We consume and produce uric acid at the same time as we excrete uric acid, which is normally in balance. Uric acid levels increase when excretion decreases or when intake increases. It has to be said that 90% of the reason for the high concentration of uric acid is the decrease in excretion.

Fourth, is there any harm caused by elevated uric acid?

Some people may feel that although gout hurts, it will be fine for a few days, and it is not too harmful. However, they dare not move when gout attacks, and long-term gout can lead to joint deformity, which is equivalent to disability in a sense, which affects the quality of life. In addition, high uric acid is also easy to form kidney stones, resulting in kidney function damage and even kidney failure.

As mentioned earlier, gout, especially in women, can also increase the incidence of cardiovascular and cerebrovascular diseases.

Fifth, how to prevent gout?

Lifestyle modification is the most important way to do this, including losing weight, eating less purine-rich foods, and limiting alcohol intake (no more than 1 tael of liquor per day). To put it simply, it is "keep your mouth shut, open your legs, and watch your waistline". In addition, it is important to control high blood pressure, diabetes, and hyperlipidemia that accompany gout.

However, these types of diseases can also be improved with the lifestyle changes described above.

Sixth, which foods are rich in purines?

Since purines are components of intracellular DNA, generally speaking, the denser the cell, the more purines it contains. Specifically, animal organs (especially brain, liver, heart, and kidneys), and seafood (especially marine fish and shellfish) had the highest content; followed by fish and shrimp, meat, beans; And various cereals, vegetables, fruits, milk, eggs are lower in content. Be careful not to confuse purine content with protein content.

Gout (English: gout, scientific name: metabolic

Arthritis), also known as "hyperuricemia", is a disease caused by the accumulation of uric acid due to purine metabolism disorders, which is a kind of arthritis, also known as metabolic arthritis. The definition of gout is that the metabolism of a substance called purine in the human body is disordered, and the synthesis of uric acid (oxidative metabolites of purines) increases or decreases, resulting in hyperuricemia.

What is Gout? What are the symptoms of gout?