How to treat gout, how to treat gout

Gout disease is OK, but it requires the patient's active cooperation with the doctor, good compliance, "mouth control, legs open", strict control of diet, such as drinking more water, choosing a low-purine diet; Maintain a good lifestyle; Actively participate in physical exercise, and at the same time go to a regular hospital for examination and standardization.

In the acute phase of gout, it is generally based on rapid pain relief, and colchicine and various non-steroidal drugs can be selected. Commonly used non-steroidal drugs, such as ibuprofen, celecoxib, loxoprofen, diclofenac sodium, etc. If there are contraindications to the above drugs or adverse drug reactions cannot be tolerated, hormonal drugs can also be used**.

However, hormonal drugs need to be reduced slowly after the disease is controlled, and if the dose is reduced too quickly, it may lead to recurrence of the disease, and hormone drugs should be used with caution in some diabetic patients and patients with severe infections. In addition, in addition to the use of drugs**, it is also necessary to strictly control the diet, such as not drinking alcohol, not eating seafood, not eating animal offal and other foods that are too high in purines. In the remission period of gout, the blood uric acid should be continuously lowered, only if the uric acid will be within the normal range, can the gout continue to be avoided, and urate-lowering drugs such as febuxostat, benzbromarone, etc.

The appropriate drug should be selected according to the type of hyperuric acid in the patient**.

The main reason for gout is to pay attention to your diet and not eat foods that are high in the color of the gout.

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The clinical goals of gout include stopping the onset of acute arthritis as soon as possible, preventing arthritis**, correcting hyperuricemia, preventing complications caused by urate deposition in the kidneys and joints, and preventing the formation of uric acid kidney stones.

1. Drugs**.

1) Non-steroidal anti-inflammatory drugs: It is usually effective in relieving joint pain and swelling, and commonly used drugs include indomethacin, diclofenac, etoricoxib, etc. Nonsteroidal anti-inflammatory drugs should be continued for a period of time after pain and inflammation have resolved, in case symptoms recur or arthritis occurs due to a rapid drop in serum uric acid due to the use of urate-lowering drugs.

2) Colchicine: It is a traditional ** drug, in the acute attack of gout, it is recommended to use low-dose colchicine alone for those who have contraindications to non-steroidal anti-inflammatory drugs, which is effective and has few adverse reactions, and the effect is better when used within 48 hours. At present, it is not advisable to take large doses of colchicine because excessive doses can cause diarrhea, liver damage, or low white blood cells***.

3) Glucocorticoids: mainly used for non-steroidal anti-inflammatory drugs, colchicine** ineffective or contraindicated, renal insufficiency, in the acute attack of gout, short-term glucocorticoids alone, its efficacy and safety are similar to non-steroidal anti-inflammatory drugs. In addition, other analgesics, rest, splinting, and ice may be used to reduce pain.

2. Interictal and chronic phases**: For patients with frequent attacks of acute gouty arthritis and chronic gouty arthritis or tophi, uric acid lowering should be carried out to control the patient's blood uric acid level in the range of 300 350 mol l, which is helpful to alleviate symptoms and control the condition.

1) Allopurinol: adverse reactions include gastrointestinal symptoms, rash, drug fever, elevated liver enzymes, bone marrow suppression, etc.

2) Febuxostat: It can be used for patients with mild to moderate renal insufficiency, and the adverse reactions mainly include mild liver function abnormalities.

3) Benbromarone: adverse reactions include gastrointestinal symptoms, rash, renal colic, granulocytopenia, etc., and rare and severe hepatotoxicity.

4) Probenecid: It can inhibit the active reabsorption of urate in the proximal convoluted renal tubule, increase the excretion of urate and reduce the concentration of urate in the blood, alleviate or prevent the formation of urate nodules, reduce joint damage, and can also promote the dissolution of urate that has been formed, and it is forbidden for those who are allergic to sulfonamides.

2. Surgery**.

If necessary, surgery such as tophi removal can be chosen** to avoid joint deformation caused by long-term development. However, at present, the indications, contraindications and specific surgical methods for the exclusion of surgery** have not been completely unified. The indications of surgery should be strictly standardized, the pros and cons should be weighed, and the risk of short-term and long-term complications after surgery should be reduced while ensuring the best effect.

The treatment of gout includes general lifestyle interventions, as well as medications for acute attacks of gout. Generally** includes dietary control, avoiding the intake of high-purine foods, such as animal offal, seafood products, thick broths and other things as little as possible, in addition to avoiding overeating, avoiding alcoholism, overwork, mental stress, etc. If the patient is complicated by dyslipidemia, diabetes, hypertension, etc., these diseases will be repeated.

Once gout is acutely attacked, in the acute arthritis stage, only symptomatic pain relief can be given in the acute stage, such as the use of non-steroidal anti-inflammatory drugs, colchicine, if not the top, glucocorticoids can also be activated. After the acute phase of gout has passed, drugs** mainly include drugs that inhibit the production of uric acid and drugs that promote the excretion of uric acid, so as to reduce uric acid to a relatively safe level and minimize the acute attack of gout.

Early (generally within 24 hours) anti-inflammatory and analgesic treatment is recommended during an acute attack of gout**, and non-steroidal anti-inflammatory drugs (NSAIDs), colchicine, and glucocorticoids can effectively anti-inflammatory and analgesic and improve the quality of life of patients. Acid-lowering is not given during an acute attack**, but those who have already taken acid-lowering drugs do not need to stop taking it, so as not to cause fluctuations in blood uric acid, which may lead to prolonged attacks or recurrence.

Allopurinol or febuxostat is recommended for inhibition of uric acid production; To promote the excretion of uric acid, benzbromarone and probenecid are recommended.

It's to improve your lifestyle, don't eat some purine-rich foods, I hope my answer will be helpful to you, if you need it, welcome to come again next time!

The purpose of gout** is to: (1) terminate an acute attack with anti-inflammatory drugs; (2) daily prophylactic use of colchicine to prevent recurrent acute attacks (if the attacks are frequent); (3) By reducing the concentration of urate in body fluids, preventing the further deposition of monosodium urate crystals and eliminating the existing tophi, preventive protective measures should be aimed at two aspects, namely to prevent disability caused by bone and articular cartilage erosion and to prevent kidney damage, special should be selected according to the different periods of the disease and the severity of the disease, should be selected at the same time hypertension, hyperlipidemia and obesity, the current medical community for gout is basically the same, that is, to reduce the level of uric acid in the patient's blood to 6mg dl (357umol l) or less.

Pechonin is an inhibitor of the enzyme X0R, which is a key enzyme in the production of uric acid from purines in the body. Therefore, pecoronin can effectively reduce uric acid levels in gout patients. The drug has been in a multi-center clinical trial, with a total of more than 4,000 participants, some of whom have been followed for more than 5 years.

Hello, drink more water, try to eliminate uric acid is right, special attention should be paid to diet, at this time do not eat a diet that is easy to increase blood uric acid, such as: animal offal, beer, liquor, seafood.

Taking painkillers and anti-inflammatory drugs for gout attacks can only temporarily suppress the pain, and do not cure the disease, and the next attack will occur. At this time, it can be conditioned with traditional Chinese medicine. Feng Cao tea has no ***, real uric acid, high gout and other conditioning can better improve the symptoms and avoid often**.

What gout patients can't eat:

There are mainly the following things that gout patients cannot eat:

First, alcohol, including all alcohols, especially beer and liquor, as they can cause an increase in blood uric acid.

Second, animal internal organs, such as liver, lungs, belly, intestines, etc.

Third, broth-based foods.

Fourth, seafood products.

Fifth, legume products, such as black beans, mung beans, etc., including soy milk.

Sixth, sugar-sweetened beverages, sugar-sweetened beverages can also increase the level of blood uric acid, and the role of sugar-sweetened drinks is often prominent in adolescents, middle school students, and college students.

Seventh, beef and mutton, general hot pot is recommended for patients to eat less, because often the things in hot pot are high purine diets.

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