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Creatinine is the final metabolite of creatine. In general, the amount of creatinine produced by the body is constant every day, and serum creatinine includes endogenous creatinine and exogenous creatinine. Endogenous creatinine is produced by creatine metabolism and is related to muscle volume and muscle activity.
Exogenous creatinine is closely related to diet, and if heated animal muscle is consumed, it will cause a rapid increase in blood creatinine levels. In cases where muscle volume and activity are relatively stable, the renal tubular excretion of creatinine and the extrarenal excretion of creatinine are constant, and the level of creatinine depends on renal function when the diet is strictly controlled. If extrarenal causes of elevated creatinine are ruled out, the elevated creatinine is due to kidney disease.
If creatinine is high, risk factors and triggers for aggravating kidney injury should be excluded or removed, such as the absence of volume depletion, infection, urinary tract obstruction, and heart failure. When the trigger is removed, the damage to the kidneys can be reduced. For the increase in creatinine, the primary disease is also very important.
Immunosuppressive drugs can be used to reduce protein in the urine and protect the kidneys. At the same time, protein is restricted, salt intake is restricted, blood pressure, blood glucose, lipids, and uric acid are controlled, and water and electrolyte imbalances are corrected. Depending on the blood creatinine, the need for hemodialysis is determined**.
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If it is just a measurement, it has no reference meaning. If there is a concomitant increase in uric acid, it is evidence of kidney damage. However, if your index is not significantly increased, it does not indicate that there is a problem with the kidneys.
You check again, check before fasting, and the previous meal should be light, if the result is normal, it means that it is just a matter of diet. If you have health problems, you can go to Yiwen Doctor to find a doctor and listen to the doctor's advice.
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At the age of 20, creatinine of 53-106umol L is normal, and above 106 should be considered high.
Creatinine is a product of muscle metabolism in the human body, and it is mainly filtered out of the body by glomerular sources. 1mg of creatinine can be produced per 20g of muscle metabolism, and when the intake of meat food is stable, the body's muscle metabolism does not change significantly, and the production of creatinine will be relatively constant.
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Creatinine is as high as more than 600 mol l depending on the specific situation, if it is more than 600 mol l caused by diabetic nephropathy, it is recommended to undergo dialysis in advance, of course, the blood creatinine standard for dialysis is 707 mol l, although it does not reach the standard of 707 mol l, but it is recommended to carry out dialysis in advance according to renal failure caused by diabetes.
If it is renal failure caused by other reasons, the blood creatinine of more than 600 mol l can be conservatively with drugs**, it is recommended to control blood pressure, correct anemia, control calcium, correct electrolyte disorders, etc., and try to maintain blood creatinine at more than 600 mol l through drugs including traditional Chinese medicine**. Of course, it will eventually progress to the uremia stage, and it will continue to develop, but through the active use of drugs, the failure of kidney function can be delayed as much as possible, and the further increase of blood creatinine can be delayed as much as possible, but in the end, the fact that blood creatinine will not be further increased.
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Creatinine is one of the laboratory indicators to measure kidney function, generally speaking, the kidneys compensate for the ability to be strong, when the kidney is not damaged to a certain extent, the patient often has no uncomfortable symptoms, when the glomerular filtration rate drops to more than 50% of the normal, the blood creatinine begins to rise rapidly, only seriously exceeds the normal value of blood creatinine (due to the different measurement methods in various places, the normal value of blood creatinine is also different, and the general normal range is 40--120umol l before the kidney is damaged.
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Disease analysis: Creatinine is a product of muscle metabolism in the human body, and 1mg of creatinine can be produced for every 20g of muscle metabolism. Creatinine is mainly excreted by glomeruli, an important part of the kidneys.
Creatinine in the blood comes from exogenous and endogenous products, exogenous creatinine is a product of the metabolism of meat food in the body; Endogenous creatinine is a product of muscle tissue metabolism in the body. When the intake of meat foods is stable. There is no major change in the body's muscle metabolism, and the production of creatinine will be relatively constant.
Suggestions: If only the blood creatinine is elevated in the renal function test, and the others are within the normal range, the clinical nephrologist will generally ask him to be checked again three days later, and other related examinations can be improved, such as urine routine examination, renal ultrasound examination, blood routine examination, etc., to confirm whether it is kidney disease.
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It is not very much to exceed the standard, and it is not excluded that it is physiological, such as diet, exercise, etc., and it is recommended to recheck it after 2 weeks.
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Do you have other medical conditions such as high blood pressure, diabetes, lupus, etc., and if so, you must be active**Primary disease.
The creatinine is slightly higher, and you can take some traditional Chinese medicine to relieve turbidity and toxin, but the specific prescription needs to meet before it can be prescribed. Therefore, it is recommended that you go to the nephrology department or nephrology department of the Chinese medicine hospital**, which can be reversed in the early stage, and it is difficult to say in the late stage.
Also, if you only have a high creatinine, you can check it again in a few days, remember to fast for eight hours before the test, and it is best to eat a light diet three days before the test, so that it will not affect the results.
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1.Specific dietary contraindications for renal insufficiency are as follows:
1. Supplement enough calories: Due to the restriction of protein intake, the intake of rice is also limited, so it is easy to cause insufficient calories, at this time, the original protein in the body will be consumed, but the urea will increase, and the resistance will become worse, so it is necessary to eat more high-calorie and low-protein foods (sugars such as sugar, honey, fruit sugar, etc.) after activities; Oils and protein powders such as:
Winter flour, West Valley rice, etc.).
2. Limit protein intake: Under the strict restriction of protein intake, patients should try to choose good protein** (such as meat, eggs, milk protein quality is better), in order to make full use of repair or maintain muscle strength, beans (except soybeans), stone fruits, gluten products, cereals, flour products, sweet potatoes, taro, potatoes, vegetables, fruits contain poor protein quality, will create more waste, increase the burden on the kidneys. Protein intake should be controlled at grams per kilogram of body weight, e.g
If you weigh 50 kg, your protein intake should be around 30 grams per day.
3. Limit potassium ions: When the kidney function is not good, the human body may not be able to effectively remove excess potassium, and too high blood potassium can easily cause serious abnormal cardiac conduction and contraction, and even death. Therefore, it is advisable to eat less vegetables with high potassium content (e.g
Shiitake mushrooms, mustard greens, cauliflower, spinach, water spinach, bamboo shoots, tomatoes, carrots, pumpkin, guava) and fruits (such as: loquat, peaches, willow dices, hard persimmons, oranges, etc.), try to avoid raw vegetable salad, others such as: coffee, strong tea, chicken essence, beef essence, ginseng essence, thick broth, soy sauce, bag salt and other potassium content is also high, should be eaten as little as possible.
4. Limit sodium ions: Too much sodium ions in the body can easily cause increased blood pressure, edema, ascites, pulmonary hydrops, and heart failure. Salt, soy sauce, monosodium glutamate, tomato paste, sand tea sauce, vinegar, etc. in food contain a lot of sodium, so less salt should be added when stir-frying.
When eating out, you can use plain water to dilute the salt in the food first.
5. Limit phosphorus ions: The main function of phosphorus is to strengthen bones, uremia patients due to the inability of the kidneys to work normally, so excess phosphorus will accumulate in the blood, resulting in hyperphosphatemia, resulting in itching and bone lesions. Foods with higher phosphorus content are:
Dairy products, soft drinks, cola, fermented foods (healthy sugar), organ meats, dried legumes, whole grains (brown rice, whole wheat bread), eggs, dried fish, etc., should be consumed with caution.
6. How to limit water: Due to the decrease in urine output, uremia patients will be retained in the body by mouth, resulting in edema, increased blood pressure, and even pulmonary edema, so uremia patients must strictly limit their daily fluid intake, usually the amount of liquid intake through the mouth is about equal to the daily urine output plus 500 ml. If you sweat a lot, you can increase it as appropriate.
But don't forget to measure your weight every day as a reference for drinking water for yourself.
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A serum creatinine higher than normal indicates that renal function has declined, and it is necessary to calculate the creatinine clearance rate, with a calculation formula and a stage of renal insufficiency
1. Calculation of creatinine clearance.
Creatinine clearance CCR = [(140-age) body weight (kg)] serum creatinine (for females, as calculated
2. Stages of chronic renal insufficiency.
Normal renal function: creatinine clearance CCR 120 80 ml Partial renal insufficiency compensatory phase: creatinine clearance CCR 80 50 ml Partial azotemia phase:
Creatinine clearance CCR 50 20 ml Renal failure phase: Creatinine clearance CCR 20 10 ml Uremia phase: Creatinine clearance CCR 10 ml The main factors that cause a decline in kidney function are:
Massive proteinuria, hematuria, hypertension, hyperlipidemia, diabetes mellitus with uncontrolled blood sugar, smoking, use of nephrotoxic drugs, etc., should go to the nephrology department of the local public hospital above the top three to receive formal examination and **, the purpose is to delay the decline of renal function.
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If the creatinine is slightly high, it's fine.
If it's too high, you need it.
If it's high enough, you'll need dialysis!
You'd better write out the values, otherwise you won't be able to say how.
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If you were in good health and had no symptoms, you don't have to worry if the value is a little high. Drink plenty of water, eat less protein-rich foods, and urinate more. I'll see it again in two weeks.
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No, you still have to go to the hospital for a detailed examination to determine**, targeted**.
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It is difficult to judge the high creatinine alone, and it is best to write a detailed report of biochemistry, blood routine, and urine routine results. If only the creatinine is high and all other tests are normal, it may be caused by a cold or overexertion, so don't worry.
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There are two kinds of blood creatinine: exogenous creatinine is the product of the metabolism of meat food in the body, and endogenous creatinine is the product of muscle tissue metabolism in the body. When the intake of meat is stable, and there is no major change in the body's muscle metabolism, the production of creatinine will be relatively constant, and there will be no high creatinine. In other words, if kidney function is impaired, blood creatinine and creatinine will be high. >>>More