What happens if the demyelination is severe? How terrible is demyelination?

Demyelination is severe and paralyzing.

Demyelination occurs when the myelin sheath of the axons of the cerebrospinal cord is lost. There are two categories: myelin destruction; Disorders of myelination. Spinal inflammatory demyelinating diseases are currently considered to be immune-mediated diseases, and their clinical features are:

The patients were children and young adults;

Acute onset, common history of cold, fever, infection, rash, vaccination, cold, childbirth or surgery 1 month before the illness;

A thorough neurological examination often reveals evidence of other central nervous system involvement in addition to spinal cord symptoms and signs;

cerebrospinal fluid examination is positive for oligoclonal bands;

Electrophysiology and MRI can detect some subclinical lesions in the brain; MRI reveals abnormal signals of white matter in the brain. Some myelittic demyelinating lesions present:"Pseudoneoplasia"Manifestations, the MRI shows a mild mass effect, mild edema around it, and there may be patchy hemorrhagic signals, which can easily be misdiagnosed as spinal cord tumors. At present, the effect of internal medicine drugs** is not good.

Therefore, neurosurgical intervention is inevitable and necessary.

Demyelinating myelitis is usually acute multiple sclerosis (MS) spinal type, and the clinical presentation is similar to that of postinfectious myelitis, but the progression is slow, and the disease usually peaks within 1 to 3 weeks. The prodromal infection may be subtle, usually incomplete transverse lesions, with weakness or paralysis of one or both lower extremities, with numbness, the level of sensory impairment is inconspicuous or two-plane, and urinary and fecal disorders are present. Evoked potentials and MRI may reveal lesions elsewhere in the CNS.

Demyelination is sometimes scary because there are many harms associated with demyelinating diseases

Demyelination is a terrible place 1Acute disseminated encephalomyelitis is a demyelinating disease characterized by extensive inflammatory demyelinating changes in the white matter of the brain and spinal cord. Symptoms and signs of diffuse brain damage, such as hemiplegia, aphasia, cranial nerve palsy, convulsions, and psychiatric disorders, are prominent.

Demyelination is a terrible place 2Acute hemorrhagic leukoencephalitis is a fulminant form of acute disseminated encephalomyelitis. Acute onset, severe symptoms, and poor prognosis.

Demyelination is a terrible place 3Diffuse sclerosis is a demyelinating encephalitis characterized by diffuse white matter with large areas of inflammatory myelin loss as pathological features.

Demyelination is a terrible place 4Multiple sclerosis is a demyelinating disease characterized by multiple foci of white matter in the central nervous system and remission of the course of the disease. Most of the onset is acute or subacute, and the symptoms are complex due to the multiple lesions, which vary depending on the location of the lesion.

The terrible place of demyelination can cause paraplegia, fasciculation, or segmental sensory impairment when the lesion is located in the spinal cord; unilateral or bilateral neuritis or retrobulbar optic neuritis when located in the optic nerve; cranial nerve palsy and limb paralysis when located in the brainstem; ataxia, limb tremor (intention tremor), and nystagmus when located in the cerebellum; When located in the cerebral hemispheres, symptoms such as hemiplegia, aphasia, and intellectual and mental disorders occur.

The myelin sheath is an important component of myelinated nerve fibers and is heavily involved in nerve signaling. Demyelination can greatly affect the process of nerve signaling, which is of course scary.

In spinal cord demyelinating lesions, patients may have sensory deficits below the lesion segment, which can be manifested as numbness and pain, and in severe cases, limb motor dysfunction can also occur, and can also have urinary and urinary disorders, including urinary and urinary retention. If the patient has a lesion of the cervical spinal cord, it may also affect the respiratory muscles, which can cause paralysis of the respiratory muscles, which can easily cause respiratory failure and may cause death.

It can occur at any age and has a similar incidence in both men and women. Its characteristic pathology is the demyelination of nerve fibers and relatively intact nerve cells. The function of the myelin sheath is to protect neurons so that nerve impulses can be transmitted rapidly on neurons.

Demyelination affects nerve impulse transmission. Acute demyelinating disease regenerates nerve myelin with little effect on its function. Chronic demyelinating neuropathy is characterized by incomplete functional recovery due to repeated demyelination, nerve coarsening, and axonal loss.

The most severe ones can lead to vegetative and even death.

There is no effective method for the disease at hand, and the main purpose of this type of disease is to inhibit the progression of inflammatory demyelinating lesions in the acute phase and avoid factors that may precipitate it.

Patients with early-stage demyelination can be treated with immunosuppressants**, plasma exchange**, and glucocorticoids**, while patients with advanced demyelination can choose to be supportive and symptomatic**.

The choice of the method of demyelination needs to clarify the cause of this type of disease, which is generally believed to be due to the interaction of autonomic nervous system disorders, viral infections, endocrine genetic factors, and congenital developmental abnormalities.

Demyelination refers to the damage of the myelin sheath that occurs after the formation of myelination, and demyelinating diseases are a group of diseases characterized by the loss of nerve myelin and relatively mild involvement of neuronal inclusions and axons, including hereditary and acquired. Hereditary demyelinating diseases mainly refer to leukodystrophy, which is more common in children.

Of course, it's more serious.

In the case of demyelination, the following is recommended

In the first case, if this demyelination is caused by cerebrovascular disease, such as cerebral small vessel disease will cause multiple demyelination of white matter, the main way to deal with it is that the patient must pay attention to maintaining a stable mood, control blood pressure, achieve a low-salt and low-fat diet, can take anti-platelet aggregation drugs, and some drugs that reduce blood lipids and stabilize atherosclerosis**.

In the second case, if the demyelination is caused by multiple sclerosis and neuromyelitis optica, the first way is to use some gamma globulin, glucocorticoids, and long-term follow-up to adjust the dose of the drug.

In the third case, if the peripheral nerve is demyelinated, such as acute Guillain-Barré, the modality is mainly gamma globulin and B vitamins.

In the acute attack of demyelinating lesions, you can choose a large dose of hormonal drugs to attack**, such as methylprednisolone, or dexamethasone. If the patient's body is not able to tolerate hormonal drugs, gamma globulin injection can be selected, and in severe cases, plasma exchange can be selected**.

The demyelinating approach mainly includes two aspects: immunity against neurological recovery and support for neurological recovery.

Immunity ** most commonly used hormones, immunosuppressants and gamma globulin, etc., the main role is to inhibit the inflammatory response, reduce the damage of inflammation to the nerves, according to the specific type of disease of the patient, whether it is easy to **, etc., to decide the choice of specific drugs and course of treatment, generally in the acute phase is the use of high-dose methylprednisolone shock**, and then gradually reduce the dose and change to prednisone oral maintenance for a period of time, can also use gamma globulin shock**, if the patient's disease is easy**, In the later stage, long-term use of hormones or combined immunosuppressants, such as azathioprine, is required**.

For symptomatic support of nutritional nerves**, citicoline, idebenone, vitamin B1, methylcobalamin, and oxiracetam and other drugs are generally used, and their mechanism of action is to promote the metabolism of nerve cells and the repair of myelin sheaths.

Early onset is not severe, and it gradually worsens after chronic exacerbations** and late recurrence of central damage leading to paralysis.

Demyelinating disease is an acute onset or subacute damage to the white matter of the central nervous system, the sooner the recovery, the better, Chinese medicine is called impotence syndrome, and according to the symptoms can be determined as rheumatism, prickly heat, dizziness, bone, dizziness, blue blindness, paralysis is called body inertia, spinal cord symptoms are serious, the brain is seen in chronic subacute lesions damage nerves resulting in dysfunction after magnetic resonance can be found, if the delay of the damaged nerve secondary ischemic degeneration will occur multiple sclerosis, When the disease is severe, it can invade the anterior horn cells of the spinal cord and the nerve nucleus of the brainstem, as well as the pyramidal cells of the cerebral motor cortex, which is life-threatening, and is mostly caused by abnormal genetic immunity or viral infection, trauma and hypoxia. In the early stage, most of them were hormones and nutrition, but the efficacy was difficult to control and the recovery was false, and it would be more likely to be after the excitement did not stop. Due to the loss of myelin caused by this disease, neurological damage is caused by severe secondary axonal damage, which further aggravates neurological symptoms, and delays the onset of sclerosis and necrosis of the entire central nervous system, resulting in spastic paralysis and life-threatening

No information is provided, but only a theoretical **plan can be provided for you: **In addition to normal hormones**, it can be gradually replaced by natural hormones and is non-toxic to people***. It should enhance the body's immune function and improve the body's ability to resist diseases.

Nutrition of the nerves, the combination of traditional Chinese and Western medicine to expand the microcirculation so that the damaged residual nerves can get sufficient blood supply, to prevent the disease from further developing. Regulates neuromalacia, relieves scarring, relieves spasticity, and creates favorable conditions for nerve recovery. At the same time, it stimulates and activates the nerve cells that are paralyzed and shocked, so that the body produces viral antibodies and no longer achieves the purpose of regenerating and repairing damaged nerves to obtain the best recovery

If you need help, please send magnetic resonance for your guidance.

Hello, according to your description, combined with your age, the main ones are headaches, dizziness, numbness of limbs, and difficulty standing, it should be that the doctor gave you an MRI of the skull and spinal cord before he can tell you that you have demyelinating disease, this situation is likely to be a multiple sclerosis, the cause of this disease is not too clear, and general studies have shown that it is related to immune factors.

There are many reasons for the aggravation of the disease, and it will get worse over time, so be sure to find the right way**.

How about now, you can try Chinese medicine**.